GB1527590A - Systems for indicating the variation in radioactivity within a patient's cardiac cycle from a tracer substance in the blood - Google Patents

Systems for indicating the variation in radioactivity within a patient's cardiac cycle from a tracer substance in the blood

Info

Publication number
GB1527590A
GB1527590A GB7250/76A GB725076A GB1527590A GB 1527590 A GB1527590 A GB 1527590A GB 7250/76 A GB7250/76 A GB 7250/76A GB 725076 A GB725076 A GB 725076A GB 1527590 A GB1527590 A GB 1527590A
Authority
GB
United Kingdom
Prior art keywords
memory
counter
channel
generator
radioactivity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB7250/76A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ohio Nuclear Inc
Original Assignee
Ohio Nuclear Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ohio Nuclear Inc filed Critical Ohio Nuclear Inc
Publication of GB1527590A publication Critical patent/GB1527590A/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/40Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment with arrangements for generating radiation specially adapted for radiation diagnosis
    • A61B6/4057Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment with arrangements for generating radiation specially adapted for radiation diagnosis by using radiation sources located in the interior of the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/026Measuring blood flow
    • A61B5/0275Measuring blood flow using tracers, e.g. dye dilution
    • A61B5/02755Radioactive tracers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/318Heart-related electrical modalities, e.g. electrocardiography [ECG]
    • A61B5/346Analysis of electrocardiograms
    • A61B5/349Detecting specific parameters of the electrocardiograph cycle
    • A61B5/352Detecting R peaks, e.g. for synchronising diagnostic apparatus; Estimating R-R interval
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/74Details of notification to user or communication with user or patient ; user input means
    • A61B5/7475User input or interface means, e.g. keyboard, pointing device, joystick
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/42Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment with arrangements for detecting radiation specially adapted for radiation diagnosis
    • A61B6/4208Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment with arrangements for detecting radiation specially adapted for radiation diagnosis characterised by using a particular type of detector
    • A61B6/4258Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment with arrangements for detecting radiation specially adapted for radiation diagnosis characterised by using a particular type of detector for detecting non x-ray radiation, e.g. gamma radiation
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01TMEASUREMENT OF NUCLEAR OR X-RADIATION
    • G01T1/00Measuring X-radiation, gamma radiation, corpuscular radiation, or cosmic radiation
    • G01T1/16Measuring radiation intensity
    • G01T1/161Applications in the field of nuclear medicine, e.g. in vivo counting
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/50Clinical applications
    • A61B6/507Clinical applications involving determination of haemodynamic parameters, e.g. perfusion CT

Abstract

1527590 Cardiac measurement by radioactivity OHIO-NUCLEAR Inc 24 Feb 1976 [6 Nov 1975] 07250/76 Heading G1A A system for indicating the variation of radioactivity within a patient's cardiac cycle has timing means 28 for determining a plurality of corresponding sampling intervals in each of a plurality of cardiac cycles, means 26 for counting the number of radiations from a selected heart blood pool location in each interval and an indicator of the cumulative amount of radiation counted in the corresponding sample intervals of the plurality of cardiac cycles. Analyser 20 produces digital output pulses for gamma rays (i.e. when its input voltages are in a certain range). These are counted by counter 26, cleared at the beginning of each interval by generator 28. Input channel counter 36 is reset by the ECG signal from detector 10 and clocked by generator 28. During each sampling interval memory 34 stores cumulative data and its corresponding memory channel is switched by counter 36. This data is automatically added by adder 32 to the count already stored after which control of the memory address is switched from counter 36 to the video display system, so that time base generator 42 controls the read-out of memory 34. Each channel's contents appear at the output simultaneously with each line SYNC pulse. The output of comparator 48 causes a bar to be drawn on the corresponding line of the raster of CRT 40 of length proportional to the number stored in the corresponding channel of memory 34. CRT 40 is orientated so that this length is vertical. For a single pass mode of operation, opening mode switch 38 prevents the initiation of counter 36 by the patients R-wave and it is only reset by the action of a switch, and is automatically terminated after counting a certain number of channels. Generator 52 generates a digital graticule signal gated by ECLUSIVE OR gate 54 to CRT 40 such that the grid pattern is not obscured by the data image. Rate control 28a varies the sampling intervals over a 4:1 range. Counter 36 can be adjusted to switch in ¢ or “ of the number of memory channels. Channel number selector 56 can be used to multiply the sampling interval by 2 or 4 and to correct comparator 48 to interrogate each memory channel for 2 or 4 lines to lower the resolution of the display.
GB7250/76A 1975-11-06 1976-02-24 Systems for indicating the variation in radioactivity within a patient's cardiac cycle from a tracer substance in the blood Expired GB1527590A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US62952175A 1975-11-06 1975-11-06

Publications (1)

Publication Number Publication Date
GB1527590A true GB1527590A (en) 1978-10-04

Family

ID=24523352

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7250/76A Expired GB1527590A (en) 1975-11-06 1976-02-24 Systems for indicating the variation in radioactivity within a patient's cardiac cycle from a tracer substance in the blood

Country Status (12)

Country Link
JP (1) JPS6052387B2 (en)
AU (1) AU501106B2 (en)
BE (1) BE848072A (en)
BR (1) BR7607399A (en)
CA (1) CA1054262A (en)
DE (1) DE2617886A1 (en)
FR (1) FR2331038A1 (en)
GB (1) GB1527590A (en)
IL (1) IL50764A (en)
NL (1) NL7611844A (en)
SU (1) SU708987A3 (en)
ZA (1) ZA766228B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112258432A (en) * 2020-10-23 2021-01-22 成都大学 Neutron-gamma discrimination method based on composite structural element mathematical morphology

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4092980A (en) * 1976-01-12 1978-06-06 G. D. Searle & Co. Fibrinogen monitor
US4294259A (en) * 1977-11-25 1981-10-13 Bios Inc. Method and apparatus for characterizing blood flow through the heart
US4245646A (en) * 1978-06-19 1981-01-20 Picker Corporation Nuclear cardiology apparatus and method
DE3150554A1 (en) * 1980-12-22 1982-10-21 Medtronic, Inc., 55440 Minneapolis, Minn. ARRANGEMENT FOR NON-INVASIVE EVALUATION OF THE FUNCTIONAL BEHAVIOR OF PATIENTS

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3221731A (en) * 1962-05-31 1965-12-07 Annis Martin Apparatus for evaluating the condition of the heart muscle
FR89661E (en) * 1965-02-22 1967-07-28 Aquitaine Petrole Apparatus for measuring the logarithmic decrement of an exponential function and its application to the measurement of blood flow by radioactive tracer
US3824399A (en) * 1971-01-27 1974-07-16 Saab Scania Ab Method of in vivo examination of organ functions

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112258432A (en) * 2020-10-23 2021-01-22 成都大学 Neutron-gamma discrimination method based on composite structural element mathematical morphology
CN112258432B (en) * 2020-10-23 2021-09-21 成都大学 Neutron-gamma discrimination method based on composite structural element mathematical morphology

Also Published As

Publication number Publication date
BR7607399A (en) 1977-09-20
CA1054262A (en) 1979-05-08
SU708987A3 (en) 1980-01-05
DE2617886A1 (en) 1977-05-12
FR2331038A1 (en) 1977-06-03
JPS5259977A (en) 1977-05-17
AU501106B2 (en) 1979-06-14
NL7611844A (en) 1977-05-10
JPS6052387B2 (en) 1985-11-19
AU1266176A (en) 1977-10-13
BE848072A (en) 1977-03-01
IL50764A0 (en) 1976-12-31
ZA766228B (en) 1977-09-28
IL50764A (en) 1979-03-12
FR2331038B1 (en) 1982-10-22

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee