GB1523825A - Induction of ovulation with partially desialylated human chlorionic gonadotropin - Google Patents
Induction of ovulation with partially desialylated human chlorionic gonadotropinInfo
- Publication number
- GB1523825A GB1523825A GB6259/76A GB625976A GB1523825A GB 1523825 A GB1523825 A GB 1523825A GB 6259/76 A GB6259/76 A GB 6259/76A GB 625976 A GB625976 A GB 625976A GB 1523825 A GB1523825 A GB 1523825A
- Authority
- GB
- United Kingdom
- Prior art keywords
- ovulation
- induction
- partially desialylated
- desialylated human
- partially
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 230000016087 ovulation Effects 0.000 title abstract 2
- 102000006771 Gonadotropins Human genes 0.000 title 1
- 108010086677 Gonadotropins Proteins 0.000 title 1
- 239000002622 gonadotropin Substances 0.000 title 1
- 230000006698 induction Effects 0.000 title 1
- 241001465754 Metazoa Species 0.000 abstract 1
- SQVRNKJHWKZAKO-PFQGKNLYSA-N N-acetyl-beta-neuraminic acid Chemical group CC(=O)N[C@@H]1[C@@H](O)C[C@@](O)(C(O)=O)O[C@H]1[C@H](O)[C@H](O)CO SQVRNKJHWKZAKO-PFQGKNLYSA-N 0.000 abstract 1
- 229960004407 chorionic gonadotrophin Drugs 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 208000000509 infertility Diseases 0.000 abstract 1
- 230000036512 infertility Effects 0.000 abstract 1
- 231100000535 infertility Toxicity 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/12—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Abstract
1523825 Partially desialylated human chorionic ganatotrophin SERONO LABORATORIES INC 17 Feb 1976 [17 Feb 1975] 06259/76 Heading A5B Pharmaceutical compositions for inducing ovulation and treating infertility in female animals comprise partially desialylated human chorionic gonadotrophin and a pharmaceutically acceptable carrier. The gonadotrophin is preferably desialylated to 15-35% (i.e. 15-35% of the total N-acetylneuraminic acid residues have been removed). The compositions are suitably in injectable form.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT48202/75A IT1057895B (en) | 1975-02-17 | 1975-02-17 | HUMAN CHORIONIC GONADOTROPINE PARALLEL DESALINIZED TO INDUCE OUVULATION |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1523825A true GB1523825A (en) | 1978-09-06 |
Family
ID=11265181
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB6259/76A Expired GB1523825A (en) | 1975-02-17 | 1976-02-17 | Induction of ovulation with partially desialylated human chlorionic gonadotropin |
Country Status (8)
Country | Link |
---|---|
US (1) | US4062942A (en) |
BE (1) | BE838657A (en) |
CA (1) | CA1059030A (en) |
DE (1) | DE2606309C3 (en) |
FR (1) | FR2300573A1 (en) |
GB (1) | GB1523825A (en) |
IL (1) | IL49054A (en) |
IT (1) | IT1057895B (en) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4196123A (en) * | 1978-11-20 | 1980-04-01 | Eugenia Rosemberg | Hybrid chorionic gonadotropin preparations and methods for stimulating ovulation using same |
US4589402A (en) * | 1984-07-26 | 1986-05-20 | Serono Laboratories, Inc. | Method of in vitro fertilization |
US4970071A (en) * | 1985-01-18 | 1990-11-13 | Mcmichael John | Immunotherapeutic methods and compositions employing antigens characteristic of non human malignant neoplasms |
US4966753A (en) * | 1987-08-18 | 1990-10-30 | Molecular Rx, Inc. | Immunotherapeutic methods and compositions employing antigens characteristic of malignant neoplasms |
US5384132A (en) * | 1990-03-20 | 1995-01-24 | Akzo N.V. | Stabilized gonadotropin containing preparations |
US5270057A (en) * | 1990-03-20 | 1993-12-14 | Akzo N.V. | Stabilized gonadotropin containing preparations |
IE64738B1 (en) * | 1990-03-20 | 1995-09-06 | Akzo Nv | Stabilized gonadotropin containing preparations |
US5416071A (en) * | 1991-03-12 | 1995-05-16 | Takeda Chemical Industries, Ltd. | Water-soluble composition for sustained-release containing epo and hyaluronic acid |
EP0739352A1 (en) * | 1994-01-20 | 1996-10-30 | Akzo Nobel N.V. | New composition of glycoprotein isoforms having follicle stimulating activity |
DE60212425T2 (en) * | 2001-10-22 | 2006-11-09 | Applied Research Systems Ars Holding N.V. | FSH COMPOSITIONS HAVING A HIGH SIALYLATION RATE AND THEIR USE FOR THE PREPARATION OF MEDICAMENTS |
AU2005252636A1 (en) | 2004-05-17 | 2005-12-22 | The General Hospital Corporation | Compositions comprising female germline stem cells and methods of use thereof |
KR20070073879A (en) * | 2004-10-07 | 2007-07-10 | 스템 셀 테라퓨틱스 코포레이션 | Stimulation of proliferation of pluripotential stem cells through administration of pregnancy associated compounds |
EA201391523A1 (en) | 2011-04-14 | 2014-03-31 | Зе Дженерэл Хоспитэл Корпорейшн | COMPOSITIONS AND METHODS FOR ENERGY TRANSFER MITOCHONDRIA OF AUTOLOGICAL HERMINATIVE CELLS |
AU2012276038B2 (en) | 2011-06-29 | 2017-08-31 | President And Fellows Of Harvard College | Compositions and methods for enhancing bioenergetic status in female germ cells |
-
1975
- 1975-02-17 IT IT48202/75A patent/IT1057895B/en active
-
1976
- 1976-02-17 IL IL49054A patent/IL49054A/en unknown
- 1976-02-17 CA CA245,964A patent/CA1059030A/en not_active Expired
- 1976-02-17 BE BE164402A patent/BE838657A/en not_active IP Right Cessation
- 1976-02-17 DE DE2606309A patent/DE2606309C3/en not_active Expired
- 1976-02-17 GB GB6259/76A patent/GB1523825A/en not_active Expired
- 1976-02-17 FR FR7604293A patent/FR2300573A1/en active Granted
- 1976-02-17 US US05/658,490 patent/US4062942A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CA1059030A (en) | 1979-07-24 |
FR2300573B1 (en) | 1979-03-23 |
US4062942A (en) | 1977-12-13 |
DE2606309A1 (en) | 1976-08-26 |
IL49054A0 (en) | 1976-04-30 |
DE2606309C3 (en) | 1981-01-22 |
IT1057895B (en) | 1982-03-30 |
BE838657A (en) | 1976-08-17 |
IL49054A (en) | 1979-09-30 |
DE2606309B2 (en) | 1980-05-14 |
FR2300573A1 (en) | 1976-09-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed [section 19, patents act 1949] | ||
PE20 | Patent expired after termination of 20 years |
Effective date: 19960216 |