GB1474461A - Production of nicotinic acid - Google Patents
Production of nicotinic acidInfo
- Publication number
- GB1474461A GB1474461A GB3339474A GB3339474A GB1474461A GB 1474461 A GB1474461 A GB 1474461A GB 3339474 A GB3339474 A GB 3339474A GB 3339474 A GB3339474 A GB 3339474A GB 1474461 A GB1474461 A GB 1474461A
- Authority
- GB
- United Kingdom
- Prior art keywords
- nicotinic acid
- ammonia
- nicotinamide
- decomposition
- nicotinonitrile
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/803—Processes of preparation
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
Abstract
1474461 Nicotinic acid LUMMUS CO 29 July 1974 [15 Nov 1973 25 April 1974] 33394/74 Heading C2C Nicotinic acid is produced by combining nicotinonitrile with ammonia and an aqueous recycle containing nicotinamide and ammonium nicotinate, heating the resultant combination to 95-230‹ C. to effect hydrolysis of the nicotinonitrile and nicotinamide to effect decomposition thereof to nicotinic acid, the decomposition being effected with continuous removal of evolved ammonia, recovering a product containing nicotinic acid and an aqueous solution of ammonium nicotinate and nicotinamide, separating the nicotinic acid from the aqueous solution and recycling the latter. The hydrolysis and decomposition may be carried out simultaneously or separately; the ammonia may be removed by contacting the ammonium nicotinate countercurrently with an inert gas, e.g. steam. The nicotinonitrile used in the process may be obtained by reacting beta-picoline, 2,3- or 2,5-dimethylpyridine, 2- methyl - 3 - ethyl - pyridine, 3 - ethyl - pyridine, the nitrile of any of these alkyl-substituted pyridines, methylcyanopyridine or a mixture thereof with ammonia and vanadium pentoxide as described in Specification 1,474,462; a flow diagram is given for the combined processes.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US46388273A | 1973-11-15 | 1973-11-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1474461A true GB1474461A (en) | 1977-05-25 |
Family
ID=23841667
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB3339474A Expired GB1474461A (en) | 1973-11-15 | 1974-07-29 | Production of nicotinic acid |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB1474461A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0242535A3 (en) * | 1986-04-25 | 1988-02-03 | Degussa Aktiengesellschaft | Process for the preparation of coarse-crystalline nicotinic acid of high purity |
-
1974
- 1974-07-29 GB GB3339474A patent/GB1474461A/en not_active Expired
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0242535A3 (en) * | 1986-04-25 | 1988-02-03 | Degussa Aktiengesellschaft | Process for the preparation of coarse-crystalline nicotinic acid of high purity |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed | ||
PCNP | Patent ceased through non-payment of renewal fee |