GB1469679A - 1-amino-5,6-dihydro-morphanthridine-5,11-dione compounds and processes for their preparation - Google Patents
1-amino-5,6-dihydro-morphanthridine-5,11-dione compounds and processes for their preparationInfo
- Publication number
- GB1469679A GB1469679A GB5332474A GB5332474A GB1469679A GB 1469679 A GB1469679 A GB 1469679A GB 5332474 A GB5332474 A GB 5332474A GB 5332474 A GB5332474 A GB 5332474A GB 1469679 A GB1469679 A GB 1469679A
- Authority
- GB
- United Kingdom
- Prior art keywords
- amino
- radical
- compound
- hydrogen atom
- lower alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
- C07D223/20—Dibenz [b, e] azepines; Hydrogenated dibenz [b, e] azepines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Abstract
1469679 1 - Amino - 5,6 - dihydromorphanthridine - 5,11 - dione derivatives CHEM PHARMAZ FABRIK DR HERMANN THIEMANN GmbH 10 Dec 1974 [10 Dec 1973] 53324/74 Heading C2C Novel compounds of Formula I wherein R 1 and R 2 , which may be the same or different, each represents a hydrogen or halogen atom or a methyl, methoxy, methylthio, trifluoromethyl, nitro or acetyl radical, wherein at least one of the radicals represented by R 1 and R 2 is a hydrogen atom, R 3 represents a lower alkyl radical or a hydrogen atom, R 4 represents a lower alkyl radical or the radical in which n represents 0 or an integer from 1 to 3, and Y represents a halogen atom or an amino, mono - (lower - alkyl) - amino, di - (loweralkyl) - amino, piperidino, piperazino, or morpholino radical, and R 5 represents a hydrogen atom or a lower alkyl radical and lower denotes groups containing 1 to 3 carbon atoms, are prepared either (a) from a compound of Formula II which is mono- or di-alkylated at the 1-amino group or reacted with an #-haloalkanoic acid halide or phosgene and then with HY or (b) reacting a compound of Formula III wherein R 6 is C 1-3 alkyl with hydrazoic acid. Pharmaceutical compositions in conventional forms for oral, rectal and parenteral administration and having tranquillizing, neuroleptic and cramp relieving activity comprise an above novel compound and a carrier or diluent.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19732361467 DE2361467A1 (en) | 1973-12-10 | 1973-12-10 | 1-AMINO-5,6-DIHYDRO-MORPHANTHRIDINE 5,11-DIONE COMPOUNDS AND MEDICINAL PRODUCTS CONTAINING SUCH COMPOUNDS |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1469679A true GB1469679A (en) | 1977-04-06 |
Family
ID=5900387
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB5332474A Expired GB1469679A (en) | 1973-12-10 | 1974-12-10 | 1-amino-5,6-dihydro-morphanthridine-5,11-dione compounds and processes for their preparation |
Country Status (6)
Country | Link |
---|---|
JP (1) | JPS5088083A (en) |
CH (1) | CH605790A5 (en) |
DE (1) | DE2361467A1 (en) |
FR (1) | FR2253526B1 (en) |
GB (1) | GB1469679A (en) |
NL (1) | NL7416074A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0089322A1 (en) * | 1982-03-15 | 1983-09-21 | A. Menarini S.a.S. | Tricyclic derivatives of 5,6-dihydro-11H-dibenzo(B,E)azepin-6-one having pharmacological avtivity, and method for their preparation |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1233715B (en) * | 1989-07-14 | 1992-04-14 | Menarini Farma Ind | USE IN THERAPY OF 10-AMINO-5,6 DIIDRO-11H = DIBENZO (B, E) AZEPINA-6,11-DIONE AND DERIVATIVES, WHICH USEFUL DRUGS FOR THE TREATMENT OF URINARY INCONTINENCE |
-
1973
- 1973-12-10 DE DE19732361467 patent/DE2361467A1/en active Pending
-
1974
- 1974-11-25 CH CH1561674A patent/CH605790A5/xx not_active IP Right Cessation
- 1974-12-09 JP JP14143574A patent/JPS5088083A/ja active Pending
- 1974-12-10 GB GB5332474A patent/GB1469679A/en not_active Expired
- 1974-12-10 NL NL7416074A patent/NL7416074A/en not_active Application Discontinuation
- 1974-12-10 FR FR7440440A patent/FR2253526B1/fr not_active Expired
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0089322A1 (en) * | 1982-03-15 | 1983-09-21 | A. Menarini S.a.S. | Tricyclic derivatives of 5,6-dihydro-11H-dibenzo(B,E)azepin-6-one having pharmacological avtivity, and method for their preparation |
Also Published As
Publication number | Publication date |
---|---|
NL7416074A (en) | 1975-06-12 |
DE2361467A1 (en) | 1975-06-19 |
FR2253526B1 (en) | 1978-07-21 |
FR2253526A1 (en) | 1975-07-04 |
JPS5088083A (en) | 1975-07-15 |
CH605790A5 (en) | 1978-10-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed | ||
PCNP | Patent ceased through non-payment of renewal fee |