GB1469679A - 1-amino-5,6-dihydro-morphanthridine-5,11-dione compounds and processes for their preparation - Google Patents

1-amino-5,6-dihydro-morphanthridine-5,11-dione compounds and processes for their preparation

Info

Publication number
GB1469679A
GB1469679A GB5332474A GB5332474A GB1469679A GB 1469679 A GB1469679 A GB 1469679A GB 5332474 A GB5332474 A GB 5332474A GB 5332474 A GB5332474 A GB 5332474A GB 1469679 A GB1469679 A GB 1469679A
Authority
GB
United Kingdom
Prior art keywords
amino
radical
compound
hydrogen atom
lower alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB5332474A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
THIEMANN CHEM PHARM FAB
Original Assignee
THIEMANN CHEM PHARM FAB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by THIEMANN CHEM PHARM FAB filed Critical THIEMANN CHEM PHARM FAB
Publication of GB1469679A publication Critical patent/GB1469679A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/20—Dibenz [b, e] azepines; Hydrogenated dibenz [b, e] azepines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)

Abstract

1469679 1 - Amino - 5,6 - dihydromorphanthridine - 5,11 - dione derivatives CHEM PHARMAZ FABRIK DR HERMANN THIEMANN GmbH 10 Dec 1974 [10 Dec 1973] 53324/74 Heading C2C Novel compounds of Formula I wherein R 1 and R 2 , which may be the same or different, each represents a hydrogen or halogen atom or a methyl, methoxy, methylthio, trifluoromethyl, nitro or acetyl radical, wherein at least one of the radicals represented by R 1 and R 2 is a hydrogen atom, R 3 represents a lower alkyl radical or a hydrogen atom, R 4 represents a lower alkyl radical or the radical in which n represents 0 or an integer from 1 to 3, and Y represents a halogen atom or an amino, mono - (lower - alkyl) - amino, di - (loweralkyl) - amino, piperidino, piperazino, or morpholino radical, and R 5 represents a hydrogen atom or a lower alkyl radical and lower denotes groups containing 1 to 3 carbon atoms, are prepared either (a) from a compound of Formula II which is mono- or di-alkylated at the 1-amino group or reacted with an #-haloalkanoic acid halide or phosgene and then with HY or (b) reacting a compound of Formula III wherein R 6 is C 1-3 alkyl with hydrazoic acid. Pharmaceutical compositions in conventional forms for oral, rectal and parenteral administration and having tranquillizing, neuroleptic and cramp relieving activity comprise an above novel compound and a carrier or diluent.
GB5332474A 1973-12-10 1974-12-10 1-amino-5,6-dihydro-morphanthridine-5,11-dione compounds and processes for their preparation Expired GB1469679A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19732361467 DE2361467A1 (en) 1973-12-10 1973-12-10 1-AMINO-5,6-DIHYDRO-MORPHANTHRIDINE 5,11-DIONE COMPOUNDS AND MEDICINAL PRODUCTS CONTAINING SUCH COMPOUNDS

Publications (1)

Publication Number Publication Date
GB1469679A true GB1469679A (en) 1977-04-06

Family

ID=5900387

Family Applications (1)

Application Number Title Priority Date Filing Date
GB5332474A Expired GB1469679A (en) 1973-12-10 1974-12-10 1-amino-5,6-dihydro-morphanthridine-5,11-dione compounds and processes for their preparation

Country Status (6)

Country Link
JP (1) JPS5088083A (en)
CH (1) CH605790A5 (en)
DE (1) DE2361467A1 (en)
FR (1) FR2253526B1 (en)
GB (1) GB1469679A (en)
NL (1) NL7416074A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0089322A1 (en) * 1982-03-15 1983-09-21 A. Menarini S.a.S. Tricyclic derivatives of 5,6-dihydro-11H-dibenzo(B,E)azepin-6-one having pharmacological avtivity, and method for their preparation

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1233715B (en) * 1989-07-14 1992-04-14 Menarini Farma Ind USE IN THERAPY OF 10-AMINO-5,6 DIIDRO-11H = DIBENZO (B, E) AZEPINA-6,11-DIONE AND DERIVATIVES, WHICH USEFUL DRUGS FOR THE TREATMENT OF URINARY INCONTINENCE

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0089322A1 (en) * 1982-03-15 1983-09-21 A. Menarini S.a.S. Tricyclic derivatives of 5,6-dihydro-11H-dibenzo(B,E)azepin-6-one having pharmacological avtivity, and method for their preparation

Also Published As

Publication number Publication date
NL7416074A (en) 1975-06-12
DE2361467A1 (en) 1975-06-19
FR2253526B1 (en) 1978-07-21
FR2253526A1 (en) 1975-07-04
JPS5088083A (en) 1975-07-15
CH605790A5 (en) 1978-10-13

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee