GB1457092A - Acyloxy-phenylethanolamines - Google Patents

Acyloxy-phenylethanolamines

Info

Publication number
GB1457092A
GB1457092A GB183575A GB183575A GB1457092A GB 1457092 A GB1457092 A GB 1457092A GB 183575 A GB183575 A GB 183575A GB 183575 A GB183575 A GB 183575A GB 1457092 A GB1457092 A GB 1457092A
Authority
GB
United Kingdom
Prior art keywords
phenylethanolamines
jan
compounds
acyloxy
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB183575A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astellas Deutschland GmbH
Original Assignee
Klinge Pharma GmbH and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19742401783 external-priority patent/DE2401783C3/en
Application filed by Klinge Pharma GmbH and Co filed Critical Klinge Pharma GmbH and Co
Publication of GB1457092A publication Critical patent/GB1457092A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

1457092 o - Acyl - phenylethanolamines KLINGE PHARMA GmbH & CO 15 Jan 1975 [15 Jan 1974] 1835/75 Addition to 1358973 Heading C2C The invention comprises compounds having the general formula wherein R 1 is a methyl, methoxy or chlorine substituted benzoyloxy radical, R 2 is C 1 or C 2 alkyl, and n is 1 or 2, the substituent(s) R 1 being in the 3<SP>1</SP>-, 4<SP>1</SP>-, or 3<SP>1</SP>,5<SP>1</SP>-positions. They may be prepared by debenzylating a ketone of the formula and reducing the product to the alcohol. The compounds of the invention exhibit sympathicmimetic effects and may be used in pharmaceutical compositions.
GB183575A 1974-01-15 1975-01-15 Acyloxy-phenylethanolamines Expired GB1457092A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19742401783 DE2401783C3 (en) 1974-01-15 O-acyl-phenolethanoiamines and process for their production ng

Publications (1)

Publication Number Publication Date
GB1457092A true GB1457092A (en) 1976-12-01

Family

ID=5904839

Family Applications (1)

Application Number Title Priority Date Filing Date
GB183575A Expired GB1457092A (en) 1974-01-15 1975-01-15 Acyloxy-phenylethanolamines

Country Status (8)

Country Link
JP (2) JPS50111037A (en)
AT (1) AT342030B (en)
BE (1) BE824358R (en)
CH (1) CH583176A5 (en)
FR (1) FR2315264A2 (en)
GB (1) GB1457092A (en)
LU (1) LU71637A1 (en)
NL (1) NL7500412A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101921198A (en) * 2010-08-18 2010-12-22 潍坊幸福药业有限公司 Preparation method of etilefrine hydrochloride
CN108997261A (en) * 2017-06-07 2018-12-14 东莞市凯法生物医药有限公司 A kind of compound and the preparation method and application thereof

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1334290C (en) * 1987-02-26 1995-02-07 Adrienne Elizabeth Clarke Plant gum material and use thereof in food products
US6271001B1 (en) 1995-03-23 2001-08-07 Bio Polymers Pty. Ltd. Cultured plant cell gums for food, pharmaceutical, cosmetic and industrial applications

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO129903B (en) * 1969-04-01 1974-06-10 Sterling Drug Inc

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101921198A (en) * 2010-08-18 2010-12-22 潍坊幸福药业有限公司 Preparation method of etilefrine hydrochloride
CN101921198B (en) * 2010-08-18 2013-04-24 潍坊幸福药业有限公司 Preparation method of etilefrine hydrochloride
CN108997261A (en) * 2017-06-07 2018-12-14 东莞市凯法生物医药有限公司 A kind of compound and the preparation method and application thereof

Also Published As

Publication number Publication date
FR2315264A2 (en) 1977-01-21
AT342030B (en) 1978-03-10
ATA25575A (en) 1977-07-15
BE824358R (en) 1975-05-02
JPS5761726B2 (en) 1982-12-25
JPS50111037A (en) 1975-09-01
CH583176A5 (en) 1976-12-31
DE2401783B2 (en) 1976-08-26
DE2401783A1 (en) 1975-07-31
LU71637A1 (en) 1975-06-17
FR2315264B2 (en) 1979-06-15
NL7500412A (en) 1975-07-17
JPS56164149A (en) 1981-12-17

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Legal Events

Date Code Title Description
PS Patent sealed
732 Registration of transactions, instruments or events in the register (sect. 32/1977)
732 Registration of transactions, instruments or events in the register (sect. 32/1977)