GB1449300A - Tricyclic compounds - Google Patents

Tricyclic compounds

Info

Publication number
GB1449300A
GB1449300A GB1321576A GB1321576A GB1449300A GB 1449300 A GB1449300 A GB 1449300A GB 1321576 A GB1321576 A GB 1321576A GB 1321576 A GB1321576 A GB 1321576A GB 1449300 A GB1449300 A GB 1449300A
Authority
GB
United Kingdom
Prior art keywords
alkyl
alkanoyloxy
hydroxyalkyl
tricyclic compounds
june
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1321576A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of GB1449300A publication Critical patent/GB1449300A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D337/00Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
    • C07D337/02Seven-membered rings
    • C07D337/06Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D337/10Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D337/14[b,f]-condensed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/38Heterocyclic compounds having sulfur as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D313/00Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02Seven-membered rings
    • C07D313/06Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D313/10Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D313/14[b,f]-condensed

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Pyrane Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

1449300 Tricyclic compounds F HOFFMAN-LA ROCHE & CO AG 7 June 1974 [8 June 1973] 13215/76 Divided out of 1449297 Heading C2C Compounds of the general formula (X = O, S; R 1 = H, C 1-7 alkyl; R 4 , 5 = H, C 1-7 alkyl or hydroxyalkyl, alkanoyloxy-(C 1-7 alkyl) or NR 4 R 5 = saturated 5- or 6-membered ring which may contain O, S or a second N and/or be substituted by C 1-7 alkyl or hydroxyalkyl or alkanoyloxy-(C 1-7 alkyl); R 6 1 = halogen, CF 3 , OH, NO 2 , NH 2 , di(C 1-7 alkyl)amino, di(C 1-7 alkyl)sulphamoyl, C 1-7 alkyl, alkoxy, alkylthio or alkylsulphonyl, protected hydroxy; R 7 1, R 8 1 = H or a substituent listed for R 6 1) are prepared by reacting the corresponding 10-one with a metal derivative of the appropriate 2- propynylamine, followed by hydrolysis.
GB1321576A 1973-06-08 1974-06-07 Tricyclic compounds Expired GB1449300A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH718776A CH585746A5 (en) 1973-06-08 1973-06-08
CH718876A CH585747A5 (en) 1973-06-08 1973-06-08
CH835473A CH585745A5 (en) 1973-06-08 1973-06-08

Publications (1)

Publication Number Publication Date
GB1449300A true GB1449300A (en) 1976-09-15

Family

ID=27175724

Family Applications (4)

Application Number Title Priority Date Filing Date
GB1321476A Expired GB1449299A (en) 1973-06-08 1974-06-07 Tricyclic compounds
GB1321576A Expired GB1449300A (en) 1973-06-08 1974-06-07 Tricyclic compounds
GB2538174A Expired GB1449297A (en) 1973-06-08 1974-06-07 Tricyclic compounds
GB1321376*[A Expired GB1449298A (en) 1973-06-08 1976-06-07 Tricyclic compounds

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GB1321476A Expired GB1449299A (en) 1973-06-08 1974-06-07 Tricyclic compounds

Family Applications After (2)

Application Number Title Priority Date Filing Date
GB2538174A Expired GB1449297A (en) 1973-06-08 1974-06-07 Tricyclic compounds
GB1321376*[A Expired GB1449298A (en) 1973-06-08 1976-06-07 Tricyclic compounds

Country Status (10)

Country Link
JP (2) JPS6020392B2 (en)
AT (1) AT339318B (en)
BE (1) BE815967A (en)
CA (1) CA1030545A (en)
CH (3) CH585747A5 (en)
DE (1) DE2426040C2 (en)
FR (1) FR2232309B1 (en)
GB (4) GB1449299A (en)
LU (1) LU70255A1 (en)
NL (1) NL7407672A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR008371A1 (en) * 1996-05-30 2000-01-19 Novartis Ag AN ADDITION SALT WITH ACID OF A 10-AMINOALIFATIL-DIBENZ [B, F], OXEPINE, YOUR EMPLOYMENT; PROCEDURE FOR ITS PREPARATION, A 10-AMINOALIFATIL-DIBENZ [B, F] OXEPINE, A PHARMACEUTICAL PREPARATION CONTAINING SUCH SALT OR SUCH OXEPINE AND A PROCEDURE FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES

Also Published As

Publication number Publication date
AT339318B (en) 1977-10-10
JPS6020392B2 (en) 1985-05-21
FR2232309B1 (en) 1977-03-11
GB1449299A (en) 1976-09-15
CH585747A5 (en) 1977-03-15
NL7407672A (en) 1974-12-10
DE2426040A1 (en) 1975-01-02
ATA474574A (en) 1977-02-15
BE815967A (en) 1974-12-06
JPS6029715B2 (en) 1985-07-12
JPS5035182A (en) 1975-04-03
LU70255A1 (en) 1976-04-13
AU6936274A (en) 1975-11-27
GB1449297A (en) 1976-09-15
CH585745A5 (en) 1977-03-15
DE2426040C2 (en) 1983-01-27
JPS5823684A (en) 1983-02-12
CH585746A5 (en) 1977-03-15
FR2232309A1 (en) 1975-01-03
GB1449298A (en) 1976-09-15
CA1030545A (en) 1978-05-02

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee