GB1444395A - Carrier for proteins - Google Patents
Carrier for proteinsInfo
- Publication number
- GB1444395A GB1444395A GB3328873A GB3328873A GB1444395A GB 1444395 A GB1444395 A GB 1444395A GB 3328873 A GB3328873 A GB 3328873A GB 3328873 A GB3328873 A GB 3328873A GB 1444395 A GB1444395 A GB 1444395A
- Authority
- GB
- United Kingdom
- Prior art keywords
- water
- insoluble
- materials
- carrier material
- proteins
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 102000004169 proteins and genes Human genes 0.000 title abstract 4
- 108090000623 proteins and genes Proteins 0.000 title abstract 4
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 abstract 4
- 239000012876 carrier material Substances 0.000 abstract 4
- PNEYBMLMFCGWSK-UHFFFAOYSA-N Alumina Chemical compound [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 abstract 3
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 abstract 3
- 229910010272 inorganic material Inorganic materials 0.000 abstract 3
- 239000011147 inorganic material Substances 0.000 abstract 3
- 102000004190 Enzymes Human genes 0.000 abstract 2
- 108090000790 Enzymes Proteins 0.000 abstract 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 2
- -1 antibodies Substances 0.000 abstract 2
- 150000004984 aromatic diamines Chemical class 0.000 abstract 2
- 239000007795 chemical reaction product Substances 0.000 abstract 2
- 239000003112 inhibitor Substances 0.000 abstract 2
- 239000000463 material Substances 0.000 abstract 2
- 239000000741 silica gel Substances 0.000 abstract 2
- 229910002027 silica gel Inorganic materials 0.000 abstract 2
- 229920003176 water-insoluble polymer Polymers 0.000 abstract 2
- YBRVSVVVWCFQMG-UHFFFAOYSA-N 4,4'-diaminodiphenylmethane Chemical compound C1=CC(N)=CC=C1CC1=CC=C(N)C=C1 YBRVSVVVWCFQMG-UHFFFAOYSA-N 0.000 abstract 1
- 229920000742 Cotton Polymers 0.000 abstract 1
- 239000004952 Polyamide Substances 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 239000000440 bentonite Substances 0.000 abstract 1
- 229910000278 bentonite Inorganic materials 0.000 abstract 1
- SVPXDRXYRYOSEX-UHFFFAOYSA-N bentoquatam Chemical compound O.O=[Si]=O.O=[Al]O[Al]=O SVPXDRXYRYOSEX-UHFFFAOYSA-N 0.000 abstract 1
- 239000007853 buffer solution Substances 0.000 abstract 1
- 239000001913 cellulose Substances 0.000 abstract 1
- 229920002678 cellulose Polymers 0.000 abstract 1
- 230000008878 coupling Effects 0.000 abstract 1
- 238000010168 coupling process Methods 0.000 abstract 1
- 238000005859 coupling reaction Methods 0.000 abstract 1
- 239000011521 glass Substances 0.000 abstract 1
- 229910052588 hydroxylapatite Inorganic materials 0.000 abstract 1
- 229910044991 metal oxide Inorganic materials 0.000 abstract 1
- 150000004706 metal oxides Chemical class 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 abstract 1
- 229920002647 polyamide Polymers 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 239000002861 polymer material Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 239000012460 protein solution Substances 0.000 abstract 1
- 239000004576 sand Substances 0.000 abstract 1
- 150000004760 silicates Chemical class 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- 239000011734 sodium Substances 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- 239000004575 stone Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
- C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
- C12N11/089—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
- C12N11/096—Polyesters; Polyamides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
- C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
- C12N11/089—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
- C12N11/10—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a carbohydrate
- C12N11/12—Cellulose or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/14—Enzymes or microbial cells immobilised on or in an inorganic carrier
Abstract
1444395 Coated materials L GIVAUDAN & CIE SA 12 July 1973 [12 July 1972] 33288/73 Heading B2E [Also in Divisions Cl and C3] A protei-free carrier material for fixing proteins thereon comprises a water-insoluble polymer or water-insoluble inorganic material containing reactive oxygen functions provided with a layer of diazotised aromatic diamine. The carrier material may 'be produced by reacting the polymer or inorganic material with an aromatic diamine and diazotising the reaction product. Examples of water-insoluble inorganic materials are silicates and silicatescontaining materials such as sand, stone, silica gel or siliceous earth, bentonite, woolastonite or glass, metal oxides sudh as aluminium oxide and hydroxyl apatite. Suitable water-insoluble polymers are polyamides and cellulose e.g. cotton. Water-insoluble protein preparations may be produced by treating the carrier material with a protein solution, e.g. in a buffer solution at pH 5-7.8. Proteins which may be coupled to the carrier materials include antigens, antibodies, inhibitors such as tryptin inhibitors and enzymes. In a typical example silica gel is added to a benzene solution of 4, 4-diamino diphenyl methane and the reaction product diazotised with sodium nitrile and hydrochloric acid at 0C. The resulting particles are used for coupling with an enzyme
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1042272A CH579533A5 (en) | 1972-07-12 | 1972-07-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1444395A true GB1444395A (en) | 1976-07-28 |
Family
ID=4363063
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3328873A Expired GB1444395A (en) | 1972-07-12 | 1973-07-12 | Carrier for proteins |
Country Status (14)
| Country | Link |
|---|---|
| JP (1) | JPS4959697A (en) |
| AT (1) | AT326813B (en) |
| AU (1) | AU5578973A (en) |
| BE (1) | BE802236A (en) |
| CH (1) | CH579533A5 (en) |
| DE (1) | DE2333834A1 (en) |
| FR (1) | FR2192113B1 (en) |
| GB (1) | GB1444395A (en) |
| HU (2) | HU167605B (en) |
| IL (1) | IL42259A (en) |
| IT (1) | IT990560B (en) |
| NL (1) | NL7309663A (en) |
| SE (1) | SE7309771L (en) |
| ZA (1) | ZA733252B (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH579098A5 (en) * | 1973-02-22 | 1976-08-31 | Givaudan & Cie Sa | |
| FR2417514A1 (en) * | 1978-02-16 | 1979-09-14 | Rhone Poulenc Ind | Enzymes immobilised on inorganic supports - by attaching to bridging molecule bonded to support by an ester linkage |
| DE2963866D1 (en) * | 1978-02-16 | 1982-11-25 | Rhone Poulenc Spec Chim | Support-enzyme complexes and method for preparing them |
| DE3311889A1 (en) * | 1983-03-31 | 1984-10-11 | Byk-Mallinckrodt Chemische Produkte Gmbh, 6057 Dietzenbach | METHOD FOR IRREVERSIBLE BINDING OF PROTEIN TO POLYSTYROL SURFACES WITH THE PRESERVATION OF BIOLOGICAL ACTIVITY, POLYSTYROL SURFACES OBTAINED AND THEIR USE |
| IL83451A (en) * | 1987-08-06 | 1991-06-10 | Univ Ramot | Stabilized water soluble enzymes and a method for their preparation |
-
1972
- 1972-07-12 CH CH1042272A patent/CH579533A5/xx not_active IP Right Cessation
-
1973
- 1973-05-11 IT IT24005/73A patent/IT990560B/en active
- 1973-05-14 IL IL42259A patent/IL42259A/en unknown
- 1973-05-14 ZA ZA733252A patent/ZA733252B/en unknown
- 1973-05-14 AT AT420673A patent/AT326813B/en not_active IP Right Cessation
- 1973-05-16 AU AU55789/73A patent/AU5578973A/en not_active Expired
- 1973-05-18 HU HUGI191A patent/HU167605B/hu unknown
- 1973-05-18 HU HUGI216A patent/HU168032B/hu unknown
- 1973-07-03 DE DE19732333834 patent/DE2333834A1/en active Pending
- 1973-07-11 NL NL7309663A patent/NL7309663A/xx unknown
- 1973-07-11 JP JP48078241A patent/JPS4959697A/ja active Pending
- 1973-07-11 SE SE7309771A patent/SE7309771L/sv unknown
- 1973-07-11 FR FR7325371A patent/FR2192113B1/fr not_active Expired
- 1973-07-12 GB GB3328873A patent/GB1444395A/en not_active Expired
- 1973-07-12 BE BE133381A patent/BE802236A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CH579533A5 (en) | 1976-09-15 |
| SE7309771L (en) | 1974-01-14 |
| AT326813B (en) | 1975-12-29 |
| IL42259A (en) | 1976-09-30 |
| ZA733252B (en) | 1974-03-27 |
| HU167605B (en) | 1975-11-28 |
| DE2333834A1 (en) | 1974-01-31 |
| JPS4959697A (en) | 1974-06-10 |
| HU168032B (en) | 1976-02-28 |
| FR2192113A1 (en) | 1974-02-08 |
| NL7309663A (en) | 1974-01-15 |
| ATA420673A (en) | 1975-03-15 |
| IL42259A0 (en) | 1973-07-30 |
| AU5578973A (en) | 1974-11-21 |
| IT990560B (en) | 1975-07-10 |
| FR2192113B1 (en) | 1976-11-12 |
| BE802236A (en) | 1974-01-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP0158909B1 (en) | Immobilized enzymes, processes for preparing same and use thereof | |
| Weetall | Alkaline phosphatase insolubilized by covalent linkage to porous glass | |
| US4094743A (en) | Enzymes immobilized on chitosan | |
| Datta et al. | The purification and properties of a penicillinase whose synthesis is mediated by an R-factor in Escherichia coli | |
| Robinson et al. | Porous glass as a solid support for immobilisation or affinity chromatography of enzymes | |
| US3841971A (en) | Synergistic enzymes adsorbed within porous inorganic carriers | |
| US4186053A (en) | Insolubilized enzyme product | |
| US4201857A (en) | Novel condensation products having high activity to insolubilize proteins and protein-insolubilized products | |
| PT673427E (en) | METHOD FOR IMMOBILIZING ENZYMES TO THE CELL WALL OF A MICROBIAL CELL THROUGH THE PRODUCTION OF A FUSEOUS PROTEIN | |
| IL43904A (en) | Process for the manufacture of a diaminealdehyde condensation product and method of fixing and insolubilizing proteins and enzymes therewith | |
| EP0462182A1 (en) | Matrix metalloproteinase peptides: role in diagnosis and therapy. | |
| Afaq et al. | Immobilization and stabilization of papain on chelating sepharose: a metal chelate regenerable carrier | |
| DK141533B (en) | Polycondensation product for binding proteins or enzymes. | |
| GB1457993A (en) | Method of bonding enzymes to porous inorganic carriers | |
| GB1444395A (en) | Carrier for proteins | |
| DE69836823D1 (en) | JMY, MIT ACTIVATOR FOR P300 / CBP, FOR CODING END NUCLEIC ACID AND ITS USES | |
| EP1180114A4 (en) | Compositions, methods, and kits relating to resistin | |
| GB1532160A (en) | Method of bondine biologically active proteins to inorganic support materials | |
| Shah et al. | Gingivain; a cysteine proteinase isolated from Porphyromonas gingivalis | |
| GB1403359A (en) | Biochemical reacrions | |
| Huff et al. | Extracellular cell wall lytic enzyme from Staphylococcus aureus: purification and partial characterization | |
| DE69032883D1 (en) | ENZYMATIC BINDING OF BIOACTIVE MATERIALS TO PROTEINS | |
| ES2001864A6 (en) | Assay for varicella-zoster virus (VZV) antibodies. | |
| Uo et al. | Preparation and properties of immobilized mercuric reductase in porous glass carriers | |
| Nakagawa et al. | Enzymatic cleavage of amino terminal methionine from recombinant human interleukin 2 and growth hormone by aminopeptidase M |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |