GB1443993A - Polyene compounds - Google Patents

Polyene compounds

Info

Publication number
GB1443993A
GB1443993A GB1897475A GB1897475A GB1443993A GB 1443993 A GB1443993 A GB 1443993A GB 1897475 A GB1897475 A GB 1897475A GB 1897475 A GB1897475 A GB 1897475A GB 1443993 A GB1443993 A GB 1443993A
Authority
GB
United Kingdom
Prior art keywords
formula
group
compound
compounds
treating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1897475A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of GB1443993A publication Critical patent/GB1443993A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/06—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms
    • C07C403/08—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/06—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms
    • C07C403/10—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by etherified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/06—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms
    • C07C403/12—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/14—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by doubly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/20—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by carboxyl groups or halides, anhydrides, or (thio)esters thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/09—Geometrical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

1443993 Polyene compounds F HOFFMANN-LA ROCHE & CO AG 2 Nov 1973 [2 Nov 1972] 18974/75 Divided out of 1443992 Heading C2C The invention comprises compounds of the formula where R 15 is an alkanoyl group of 2-18 carbon atoms or an aroyl group. The compounds are prepared by treating a compound of the formula with an alxanoic or an aroic acid. Compounds of the formula where # represents a cis-configuration and #<SP>1</SP> represents a trans-configuration may be prepared by treating a compound of the formula with an alkanoic or an aroic acid. Compounds of the formula where R 15 <SP>1</SP> is H, an alkanoyl group of 2-18 carbon atoms or an aroyl group may be prepared by treating a compound of Formula I with a compound of the formula where R 4 is C 1 -C 6 alkyl, C 1 -C 6 alkyl substituted cycloalkyl, phenyl, cycloalkyl or C 1 -C 6 alkyl substituted phenyl, R 5 has any of the values accorded to R 4 or is (R 4 ) 3 Si-, m is 1-3 and n is 0-2 with the proviso that the sum of m and n is 3, to form a compound of the formula reducing the keto group to a hydroxy group and dehydrating, optionally after converting the hydroxy group into a leaving group.
GB1897475A 1972-11-02 1973-11-02 Polyene compounds Expired GB1443993A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US30316272A 1972-11-02 1972-11-02

Publications (1)

Publication Number Publication Date
GB1443993A true GB1443993A (en) 1976-07-28

Family

ID=23170788

Family Applications (3)

Application Number Title Priority Date Filing Date
GB5098873A Expired GB1443992A (en) 1972-11-02 1973-11-02 Process for the manufacture of polyene compounds
GB1897575A Expired GB1443994A (en) 1972-11-02 1973-11-02 Process for the manufactu5e of polyene compounds
GB1897475A Expired GB1443993A (en) 1972-11-02 1973-11-02 Polyene compounds

Family Applications Before (2)

Application Number Title Priority Date Filing Date
GB5098873A Expired GB1443992A (en) 1972-11-02 1973-11-02 Process for the manufacture of polyene compounds
GB1897575A Expired GB1443994A (en) 1972-11-02 1973-11-02 Process for the manufactu5e of polyene compounds

Country Status (5)

Country Link
JP (1) JPS4976838A (en)
CH (1) CH601217A5 (en)
DE (1) DE2354792A1 (en)
FR (1) FR2212329B1 (en)
GB (3) GB1443992A (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5086060A (en) * 1989-07-25 1992-02-04 Eastman Kodak Company Compound and method for treating skin for acne or psoriasis
US20230125156A1 (en) * 2020-03-31 2023-04-27 Dsm Ip Assets B.V. Process for production of vitamin a

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL74807C (en) *
US2451739A (en) * 1945-10-18 1948-10-19 Hoffmann La Roche Process for the manufacture of pentaenes
US2451738A (en) * 1945-10-18 1948-10-19 Hoffmann La Roche Process for the manufacture of pentaenes
US2451735A (en) * 1945-10-18 1948-10-19 Hoffmann La Roche Polyenes and process for the manufacture thereof
US2451736A (en) * 1945-10-18 1948-10-19 Hoffmann La Roche Polyenes and process for the manufacture thereof
DE833960C (en) * 1949-12-19 1952-03-13 Glaxo Lab Ltd Process for the preparation of 3, 7-dimethyl-1- (1-oxy-2, 6, 6-trimethylcyclohex-1-yl) -nona-3, 5, 7-trien-1-yn-9-ol

Also Published As

Publication number Publication date
JPS4976838A (en) 1974-07-24
FR2212329A1 (en) 1974-07-26
DE2354792A1 (en) 1974-05-09
GB1443992A (en) 1976-07-28
FR2212329B1 (en) 1977-09-23
GB1443994A (en) 1976-07-28
CH601217A5 (en) 1978-06-30

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee