GB1424300A - Ethod of producing guanosine by fermantation - Google Patents

Ethod of producing guanosine by fermantation

Info

Publication number
GB1424300A
GB1424300A GB2602874A GB2602874A GB1424300A GB 1424300 A GB1424300 A GB 1424300A GB 2602874 A GB2602874 A GB 2602874A GB 2602874 A GB2602874 A GB 2602874A GB 1424300 A GB1424300 A GB 1424300A
Authority
GB
United Kingdom
Prior art keywords
guanosine
methionine
producing
june
suitably
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2602874A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Co Inc
Original Assignee
Ajinomoto Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP6727673A external-priority patent/JPS5417033B2/ja
Priority claimed from JP11974973A external-priority patent/JPS5414673B2/ja
Application filed by Ajinomoto Co Inc filed Critical Ajinomoto Co Inc
Publication of GB1424300A publication Critical patent/GB1424300A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/38—Nucleosides
    • C12P19/40—Nucleosides having a condensed ring system containing a six-membered ring having two nitrogen atoms in the same ring, e.g. purine nucleosides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)

Abstract

1424300 Guanosine by fermentation AJINOMOTO CO Inc 12 June 1974 [14 June 1973 24 Oct 1973] 26028/74 Heading C2C A method for producing guanosine comprises culturing a guanosine-producing mutant strain of the genus Bacillus which requires adenine for growth and which is resistant to at least one compound selected from a sulpha drug, methionine, a methionine analogue or azaserine, under aerobic conditions in an aqueous culture medium until guanosine accumulates in the medium, and recovering accumulated guanosine from the culture medium. The mutant is also preferably resistant to 8-azaguanine and belongs to the species Bacillus subtilis or Bacillus pumilus. The sulpha drug is suitably sulphaguanidine or sulphamerazine and the methionine analogue is suitably ethionine, methyl methionine sulphonium chloride or methionine sulphoxide.
GB2602874A 1973-06-14 1974-06-12 Ethod of producing guanosine by fermantation Expired GB1424300A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP6727673A JPS5417033B2 (en) 1973-06-14 1973-06-14
JP11974973A JPS5414673B2 (en) 1973-10-24 1973-10-24

Publications (1)

Publication Number Publication Date
GB1424300A true GB1424300A (en) 1976-02-11

Family

ID=26408461

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2602874A Expired GB1424300A (en) 1973-06-14 1974-06-12 Ethod of producing guanosine by fermantation

Country Status (4)

Country Link
DE (1) DE2428548C2 (en)
FR (1) FR2233398B1 (en)
GB (1) GB1424300A (en)
IT (1) IT1015044B (en)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3222257A (en) * 1961-04-19 1965-12-07 Ajinomoto Kk Process for producing nucleosides by microorganisms
FR1467749A (en) * 1965-02-11 1967-01-27 Takeda Chemical Industries Ltd Process for the production of 5'-guanylic acid and guanosine

Also Published As

Publication number Publication date
FR2233398A1 (en) 1975-01-10
FR2233398B1 (en) 1978-01-13
IT1015044B (en) 1977-05-10
DE2428548A1 (en) 1975-01-09
DE2428548C2 (en) 1982-11-18

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee