GB1423316A - Method of coupling compounds with hydroxyl or amino groups to polymers - Google Patents
Method of coupling compounds with hydroxyl or amino groups to polymersInfo
- Publication number
- GB1423316A GB1423316A GB1208273A GB1208273A GB1423316A GB 1423316 A GB1423316 A GB 1423316A GB 1208273 A GB1208273 A GB 1208273A GB 1208273 A GB1208273 A GB 1208273A GB 1423316 A GB1423316 A GB 1423316A
- Authority
- GB
- United Kingdom
- Prior art keywords
- water
- polymeric material
- hydroxyl
- soluble compound
- agar
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001875 compounds Chemical class 0.000 title abstract 6
- 125000003277 amino group Chemical group 0.000 title abstract 4
- 125000002887 hydroxy group Chemical group [H]O* 0.000 title abstract 4
- 230000008878 coupling Effects 0.000 title abstract 3
- 238000010168 coupling process Methods 0.000 title abstract 3
- 238000005859 coupling reaction Methods 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 229920000642 polymer Polymers 0.000 title 1
- 239000000463 material Substances 0.000 abstract 7
- 229920001817 Agar Polymers 0.000 abstract 3
- 239000008272 agar Substances 0.000 abstract 3
- AFOSIXZFDONLBT-UHFFFAOYSA-N divinyl sulfone Chemical compound C=CS(=O)(=O)C=C AFOSIXZFDONLBT-UHFFFAOYSA-N 0.000 abstract 2
- 229920000936 Agarose Polymers 0.000 abstract 1
- 229920000057 Mannan Polymers 0.000 abstract 1
- 239000004372 Polyvinyl alcohol Substances 0.000 abstract 1
- 102000004142 Trypsin Human genes 0.000 abstract 1
- 108090000631 Trypsin Proteins 0.000 abstract 1
- 239000012670 alkaline solution Substances 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 150000004982 aromatic amines Chemical class 0.000 abstract 1
- 239000001913 cellulose Substances 0.000 abstract 1
- 229920002678 cellulose Polymers 0.000 abstract 1
- KPRQVUKOULNYRO-UHFFFAOYSA-N ethene;1-sulfonylethene Chemical group C=C.C=C=S(=O)=O KPRQVUKOULNYRO-UHFFFAOYSA-N 0.000 abstract 1
- 150000002337 glycosamines Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 239000002157 polynucleotide Substances 0.000 abstract 1
- 102000040430 polynucleotide Human genes 0.000 abstract 1
- 108091033319 polynucleotide Proteins 0.000 abstract 1
- 229920002451 polyvinyl alcohol Polymers 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 239000012588 trypsin Substances 0.000 abstract 1
- 238000005406 washing Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J41/00—Anion exchange; Use of material as anion exchangers; Treatment of material for improving the anion exchange properties
- B01J41/08—Use of material as anion exchangers; Treatment of material for improving the anion exchange properties
- B01J41/12—Macromolecular compounds
- B01J41/16—Cellulose or wood; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B11/00—Preparation of cellulose ethers
- C08B11/02—Alkyl or cycloalkyl ethers
- C08B11/04—Alkyl or cycloalkyl ethers with substituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0036—Galactans; Derivatives thereof
- C08B37/0039—Agar; Agarose, i.e. D-galactose, 3,6-anhydro-D-galactose, methylated, sulfated, e.g. from the red algae Gelidium and Gracilaria; Agaropectin; Derivatives thereof, e.g. Sepharose, i.e. crosslinked agarose
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F8/00—Chemical modification by after-treatment
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F8/00—Chemical modification by after-treatment
- C08F8/30—Introducing nitrogen atoms or nitrogen-containing groups
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F8/00—Chemical modification by after-treatment
- C08F8/34—Introducing sulfur atoms or sulfur-containing groups
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F2810/00—Chemical modification of a polymer
- C08F2810/20—Chemical modification of a polymer leading to a crosslinking, either explicitly or inherently
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Materials Engineering (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Abstract
1423316 Coupling polymeric materials to water-soluble compounds EXPLOATERINGS AB T BF 13 March 1973 [14 March 1972] 12082/73 Headings C3U C3H C3P and C3A A method of coupling a water-soluble compound containing one or more reactive hydroxyl and/or amino groups, e.g. an aromatic amine, an amino acid, peptide, protein, amino-sugar, nucleotide or polynucleotide to a water-insoluble but water-swellable polymeric material, e.g. polyvinyl alcohol, cellulose, agar, agarose a cross-linked mixture of agar and a mannan or carrogeenan comprises (a) reacting divinyl sulphone in aqueous alkaline solution with the polymeric material, (b) washing any unreacted divinyl sulphone from the treated material and thereafter (c) reacting the thus treated and washed polymeric material with an aqueous solution of said water-soluble compound thereby to link the polymeric material through a hydroxyl and/or amino group thereof and an ethylene sulphonyl ethylene group to a hydroxyl and/or amino group in said water-soluble compound. The polymeric material is preferably cross-linked agar and the water-soluble compound trypsin.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE325272A SE361320B (en) | 1972-03-14 | 1972-03-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1423316A true GB1423316A (en) | 1976-02-04 |
Family
ID=20261715
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1208273A Expired GB1423316A (en) | 1972-03-14 | 1973-03-13 | Method of coupling compounds with hydroxyl or amino groups to polymers |
Country Status (5)
Country | Link |
---|---|
JP (1) | JPS496065A (en) |
DE (1) | DE2312615A1 (en) |
FR (1) | FR2176033B3 (en) |
GB (1) | GB1423316A (en) |
SE (1) | SE361320B (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4372328A (en) | 1980-05-20 | 1983-02-08 | B.A.T. Cigaretten-Fabriken Gmbh | Fibrous material for tobacco smoke filter |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2430128C3 (en) * | 1974-06-22 | 1981-11-05 | Röhm GmbH, 6100 Darmstadt | Process for the preparation of carrier-bound polypeptides |
IL49752A (en) * | 1975-07-09 | 1979-07-25 | Kabi Ab | Compositions having affinity for hepatitis virus and method for hepatitis virus removal or concentration |
CA1238043A (en) * | 1983-12-15 | 1988-06-14 | Endre A. Balazs | Water insoluble preparations of hyaluronic acid and processes therefor |
SE470099B (en) * | 1984-05-17 | 1993-11-08 | Jerker Porath | Sulfone activated thioether adsorbents for separation of eg protein |
US4582865A (en) * | 1984-12-06 | 1986-04-15 | Biomatrix, Inc. | Cross-linked gels of hyaluronic acid and products containing such gels |
JPH01235593A (en) * | 1988-03-15 | 1989-09-20 | Fuji Photo Film Co Ltd | Functional organic thin membrane |
JPH01240188A (en) * | 1988-03-18 | 1989-09-25 | Fuji Photo Film Co Ltd | Functional organic thin film |
DK130991D0 (en) * | 1991-07-04 | 1991-07-04 | Immunodex K S | POLYMER CONJUGATES |
WO2008021619A2 (en) * | 2006-08-16 | 2008-02-21 | Boston Scientific Limited | Polymer particles including covalently bonded chemical species |
-
1972
- 1972-03-14 SE SE325272A patent/SE361320B/xx unknown
-
1973
- 1973-03-13 GB GB1208273A patent/GB1423316A/en not_active Expired
- 1973-03-14 DE DE19732312615 patent/DE2312615A1/en active Pending
- 1973-03-14 JP JP2991373A patent/JPS496065A/ja active Pending
- 1973-03-14 FR FR7309085A patent/FR2176033B3/fr not_active Expired
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4372328A (en) | 1980-05-20 | 1983-02-08 | B.A.T. Cigaretten-Fabriken Gmbh | Fibrous material for tobacco smoke filter |
Also Published As
Publication number | Publication date |
---|---|
SE361320B (en) | 1973-10-29 |
FR2176033A1 (en) | 1973-10-26 |
JPS496065A (en) | 1974-01-19 |
DE2312615A1 (en) | 1973-09-27 |
FR2176033B3 (en) | 1976-03-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed | ||
PCNP | Patent ceased through non-payment of renewal fee |