GB1423073A - Amines and processes for their manufacture - Google Patents
Amines and processes for their manufactureInfo
- Publication number
- GB1423073A GB1423073A GB218774A GB218774A GB1423073A GB 1423073 A GB1423073 A GB 1423073A GB 218774 A GB218774 A GB 218774A GB 218774 A GB218774 A GB 218774A GB 1423073 A GB1423073 A GB 1423073A
- Authority
- GB
- United Kingdom
- Prior art keywords
- mes
- chohch
- alk
- condensates
- phenoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D263/06—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by oxygen atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/24—Ethers with hydroxy compounds containing no oxirane rings with polyhydroxy compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Epoxy Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
1423073 Amino group-containing thioethers and derivatives thereof CIBA-GEIGY AG 17 Jan 1974 [17 Jan 1973 26 Oct 1973] 02187/74 Heading C2C Novel compounds (I) (including salts thereof): where Alk 1 is alkyl, alk 2 is alkylene, Ph is optionally substituted p-phenylene and R is alkyl or aralkyl, as well as their condensates with aldehydes, ketones and carbonic acid (i.e. the -CHOH.CH 2 -NHR moiety is converted to an oxazolidine or oxazolidin-2-one group), are made by standard methods. The following compounds are also prepared: 5 - [(4 - hydroxy - phenoxy) - methyl] - 3 - isopropyl oxazolidin - 2 - one, MeS(CH 2 ) 2 O-Ph-O-CH 2 CHOHCH 2 NH 2 , MeS(CH 2 ) 2 or 3 -O-Ph-OH, MeS(CH 2 ) 2 or 3 -O-Ph-O-CH 2 -oxirane, MeS(CH 2 ) 2 -O-Ph-O-CH 2 CHOHCH 2 Cl, 2 - [4 - (3 - bromopropoxy) - phenoxy] - tetrahydropyran and 2 - (4 - benzyloxy and -hydroxyphenoxy)-tetrahydropyrans. Pharmaceutical preparations useful as cardioselective antagonists of adrenergic #-receptor stimulants, e.g. for treating arrhythmias and angina pectoris contain (I) and/or their condensates as active ingredient.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH62173A CH576438A5 (en) | 1973-01-17 | 1973-01-17 | 1-Alkylthioalkoxy-4-(3-amino-2-hydroxypropoxy) benzenes - antagonists of beta receptor stimulants prepd. e.g. by reducing corresp. Schiff base |
CH1516473 | 1973-10-26 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1423073A true GB1423073A (en) | 1976-01-28 |
Family
ID=25685144
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB218774A Expired GB1423073A (en) | 1973-01-17 | 1974-01-17 | Amines and processes for their manufacture |
Country Status (17)
Country | Link |
---|---|
JP (1) | JPS49101343A (en) |
AR (6) | AR204334A1 (en) |
AT (2) | AT330750B (en) |
BE (1) | BE809820A (en) |
CA (1) | CA1050032A (en) |
CS (1) | CS184347B2 (en) |
DD (2) | DD110656A5 (en) |
DE (1) | DE2400693A1 (en) |
ES (1) | ES422301A1 (en) |
FR (1) | FR2213771B1 (en) |
GB (1) | GB1423073A (en) |
HU (1) | HU168750B (en) |
IE (1) | IE38736B1 (en) |
IL (1) | IL44003A (en) |
LU (1) | LU69166A1 (en) |
NL (1) | NL7400648A (en) |
SU (1) | SU520037A3 (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0002004A1 (en) * | 1977-11-07 | 1979-05-30 | Ciba-Geigy Ag | Process for the manufacture of fluorinated cationic compounds and their use as surfactants |
WO1995023779A2 (en) * | 1994-03-04 | 1995-09-08 | The Procter & Gamble Company | Process for making monoacetals of hydroquinone |
US5585525A (en) * | 1994-12-16 | 1996-12-17 | The Procter & Gamble Company | Process for making monoacetals of hydroquinone |
US6537527B1 (en) | 1994-03-04 | 2003-03-25 | Children's Hospital Medical Center | Skin lightening compositions |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZW9881A1 (en) * | 1980-06-02 | 1981-12-23 | Hoffmann La Roche | Substituted phenoxyaminopropanol derivatives |
DE3125870C2 (en) * | 1980-07-09 | 1994-09-15 | William John Louis | 3-aminopropoxyphenyl derivatives, their preparation and medicaments containing them |
JPS5746946A (en) * | 1980-07-09 | 1982-03-17 | Sandoz Ag | 3-aminopropoxyphenyl derivative, manufacture and medicine containing same |
FR2497194B1 (en) * | 1980-08-07 | 1985-06-14 | Sandoz Sa | NEW PHENOLIC COMPOUNDS |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA956632A (en) * | 1969-05-16 | 1974-10-22 | Yoshitomi Pharmaceutical Industries | Phenoxy-aminopropanol derivatives |
-
1974
- 1974-01-01 AR AR255899A patent/AR204334A1/en active
- 1974-01-01 AR AR251941A patent/AR205618A1/en active
- 1974-01-01 AR AR255900A patent/AR204105A1/en active
- 1974-01-01 AR AR255898A patent/AR204726A1/en active
- 1974-01-08 DE DE2400693A patent/DE2400693A1/en active Pending
- 1974-01-11 CS CS7700000292A patent/CS184347B2/en unknown
- 1974-01-11 IE IE66/74A patent/IE38736B1/en unknown
- 1974-01-14 IL IL44003A patent/IL44003A/en unknown
- 1974-01-14 FR FR7401149A patent/FR2213771B1/fr not_active Expired
- 1974-01-14 SU SU1985268A patent/SU520037A3/en active
- 1974-01-14 CA CA190,087A patent/CA1050032A/en not_active Expired
- 1974-01-15 ES ES422301A patent/ES422301A1/en not_active Expired
- 1974-01-15 DD DD176012A patent/DD110656A5/xx unknown
- 1974-01-15 LU LU69166A patent/LU69166A1/xx unknown
- 1974-01-15 DD DD180359A patent/DD113364A5/xx unknown
- 1974-01-16 HU HUCI1435A patent/HU168750B/hu unknown
- 1974-01-16 BE BE139875A patent/BE809820A/en unknown
- 1974-01-17 JP JP49007590A patent/JPS49101343A/ja active Pending
- 1974-01-17 GB GB218774A patent/GB1423073A/en not_active Expired
- 1974-01-17 NL NL7400648A patent/NL7400648A/xx not_active Application Discontinuation
- 1974-10-02 AR AR255897A patent/AR201518A1/en active
- 1974-10-02 AR AR255896A patent/AR201704A1/en active
-
1975
- 1975-05-26 AT AT397875A patent/AT330750B/en not_active IP Right Cessation
- 1975-05-26 AT AT397675A patent/AT330771B/en not_active IP Right Cessation
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0002004A1 (en) * | 1977-11-07 | 1979-05-30 | Ciba-Geigy Ag | Process for the manufacture of fluorinated cationic compounds and their use as surfactants |
WO1995023779A2 (en) * | 1994-03-04 | 1995-09-08 | The Procter & Gamble Company | Process for making monoacetals of hydroquinone |
WO1995023778A2 (en) * | 1994-03-04 | 1995-09-08 | The Procter & Gamble Company | Process for making monoacetals of hydroquinone |
WO1995023779A3 (en) * | 1994-03-04 | 1995-09-28 | Procter & Gamble | Process for making monoacetals of hydroquinone |
WO1995023778A3 (en) * | 1994-03-04 | 1995-09-28 | Procter & Gamble | Process for making monoacetals of hydroquinone |
US6537527B1 (en) | 1994-03-04 | 2003-03-25 | Children's Hospital Medical Center | Skin lightening compositions |
US5585525A (en) * | 1994-12-16 | 1996-12-17 | The Procter & Gamble Company | Process for making monoacetals of hydroquinone |
US5811593A (en) * | 1994-12-16 | 1998-09-22 | The Procter & Gamble Company | Monoacetals of hydroquinone |
Also Published As
Publication number | Publication date |
---|---|
NL7400648A (en) | 1974-07-19 |
CA1050032A (en) | 1979-03-06 |
FR2213771B1 (en) | 1976-09-03 |
AR204334A1 (en) | 1975-12-22 |
AR204726A1 (en) | 1976-02-27 |
DD110656A5 (en) | 1975-01-05 |
AT330771B (en) | 1976-07-26 |
ATA397875A (en) | 1975-10-15 |
AU6452474A (en) | 1975-07-17 |
AR201518A1 (en) | 1975-03-21 |
CS184347B2 (en) | 1978-08-31 |
ES422301A1 (en) | 1976-07-01 |
IE38736L (en) | 1974-07-17 |
LU69166A1 (en) | 1975-12-09 |
IL44003A (en) | 1977-05-31 |
FR2213771A1 (en) | 1974-08-09 |
AR201704A1 (en) | 1975-04-08 |
IE38736B1 (en) | 1978-05-24 |
AR205618A1 (en) | 1976-05-21 |
DE2400693A1 (en) | 1974-07-18 |
IL44003A0 (en) | 1974-05-16 |
AT330750B (en) | 1976-07-12 |
AR204105A1 (en) | 1975-11-20 |
SU520037A3 (en) | 1976-06-30 |
BE809820A (en) | 1974-07-16 |
HU168750B (en) | 1976-07-28 |
DD113364A5 (en) | 1975-06-05 |
ATA397675A (en) | 1975-10-15 |
JPS49101343A (en) | 1974-09-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed [section 19, patents act 1949] | ||
PCNP | Patent ceased through non-payment of renewal fee |