GB1423073A - Amines and processes for their manufacture - Google Patents

Amines and processes for their manufacture

Info

Publication number
GB1423073A
GB1423073A GB218774A GB218774A GB1423073A GB 1423073 A GB1423073 A GB 1423073A GB 218774 A GB218774 A GB 218774A GB 218774 A GB218774 A GB 218774A GB 1423073 A GB1423073 A GB 1423073A
Authority
GB
United Kingdom
Prior art keywords
mes
chohch
alk
condensates
phenoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB218774A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH62173A external-priority patent/CH576438A5/en
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of GB1423073A publication Critical patent/GB1423073A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10Oxygen atoms
    • C07D309/12Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/04Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D263/06Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by oxygen atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/12Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/24Ethers with hydroxy compounds containing no oxirane rings with polyhydroxy compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Epoxy Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

1423073 Amino group-containing thioethers and derivatives thereof CIBA-GEIGY AG 17 Jan 1974 [17 Jan 1973 26 Oct 1973] 02187/74 Heading C2C Novel compounds (I) (including salts thereof): where Alk 1 is alkyl, alk 2 is alkylene, Ph is optionally substituted p-phenylene and R is alkyl or aralkyl, as well as their condensates with aldehydes, ketones and carbonic acid (i.e. the -CHOH.CH 2 -NHR moiety is converted to an oxazolidine or oxazolidin-2-one group), are made by standard methods. The following compounds are also prepared: 5 - [(4 - hydroxy - phenoxy) - methyl] - 3 - isopropyl oxazolidin - 2 - one, MeS(CH 2 ) 2 O-Ph-O-CH 2 CHOHCH 2 NH 2 , MeS(CH 2 ) 2 or 3 -O-Ph-OH, MeS(CH 2 ) 2 or 3 -O-Ph-O-CH 2 -oxirane, MeS(CH 2 ) 2 -O-Ph-O-CH 2 CHOHCH 2 Cl, 2 - [4 - (3 - bromopropoxy) - phenoxy] - tetrahydropyran and 2 - (4 - benzyloxy and -hydroxyphenoxy)-tetrahydropyrans. Pharmaceutical preparations useful as cardioselective antagonists of adrenergic #-receptor stimulants, e.g. for treating arrhythmias and angina pectoris contain (I) and/or their condensates as active ingredient.
GB218774A 1973-01-17 1974-01-17 Amines and processes for their manufacture Expired GB1423073A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH62173A CH576438A5 (en) 1973-01-17 1973-01-17 1-Alkylthioalkoxy-4-(3-amino-2-hydroxypropoxy) benzenes - antagonists of beta receptor stimulants prepd. e.g. by reducing corresp. Schiff base
CH1516473 1973-10-26

Publications (1)

Publication Number Publication Date
GB1423073A true GB1423073A (en) 1976-01-28

Family

ID=25685144

Family Applications (1)

Application Number Title Priority Date Filing Date
GB218774A Expired GB1423073A (en) 1973-01-17 1974-01-17 Amines and processes for their manufacture

Country Status (17)

Country Link
JP (1) JPS49101343A (en)
AR (6) AR204334A1 (en)
AT (2) AT330750B (en)
BE (1) BE809820A (en)
CA (1) CA1050032A (en)
CS (1) CS184347B2 (en)
DD (2) DD110656A5 (en)
DE (1) DE2400693A1 (en)
ES (1) ES422301A1 (en)
FR (1) FR2213771B1 (en)
GB (1) GB1423073A (en)
HU (1) HU168750B (en)
IE (1) IE38736B1 (en)
IL (1) IL44003A (en)
LU (1) LU69166A1 (en)
NL (1) NL7400648A (en)
SU (1) SU520037A3 (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0002004A1 (en) * 1977-11-07 1979-05-30 Ciba-Geigy Ag Process for the manufacture of fluorinated cationic compounds and their use as surfactants
WO1995023779A2 (en) * 1994-03-04 1995-09-08 The Procter & Gamble Company Process for making monoacetals of hydroquinone
US5585525A (en) * 1994-12-16 1996-12-17 The Procter & Gamble Company Process for making monoacetals of hydroquinone
US6537527B1 (en) 1994-03-04 2003-03-25 Children's Hospital Medical Center Skin lightening compositions

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZW9881A1 (en) * 1980-06-02 1981-12-23 Hoffmann La Roche Substituted phenoxyaminopropanol derivatives
DE3125870C2 (en) * 1980-07-09 1994-09-15 William John Louis 3-aminopropoxyphenyl derivatives, their preparation and medicaments containing them
JPS5746946A (en) * 1980-07-09 1982-03-17 Sandoz Ag 3-aminopropoxyphenyl derivative, manufacture and medicine containing same
FR2497194B1 (en) * 1980-08-07 1985-06-14 Sandoz Sa NEW PHENOLIC COMPOUNDS

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA956632A (en) * 1969-05-16 1974-10-22 Yoshitomi Pharmaceutical Industries Phenoxy-aminopropanol derivatives

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0002004A1 (en) * 1977-11-07 1979-05-30 Ciba-Geigy Ag Process for the manufacture of fluorinated cationic compounds and their use as surfactants
WO1995023779A2 (en) * 1994-03-04 1995-09-08 The Procter & Gamble Company Process for making monoacetals of hydroquinone
WO1995023778A2 (en) * 1994-03-04 1995-09-08 The Procter & Gamble Company Process for making monoacetals of hydroquinone
WO1995023779A3 (en) * 1994-03-04 1995-09-28 Procter & Gamble Process for making monoacetals of hydroquinone
WO1995023778A3 (en) * 1994-03-04 1995-09-28 Procter & Gamble Process for making monoacetals of hydroquinone
US6537527B1 (en) 1994-03-04 2003-03-25 Children's Hospital Medical Center Skin lightening compositions
US5585525A (en) * 1994-12-16 1996-12-17 The Procter & Gamble Company Process for making monoacetals of hydroquinone
US5811593A (en) * 1994-12-16 1998-09-22 The Procter & Gamble Company Monoacetals of hydroquinone

Also Published As

Publication number Publication date
NL7400648A (en) 1974-07-19
CA1050032A (en) 1979-03-06
FR2213771B1 (en) 1976-09-03
AR204334A1 (en) 1975-12-22
AR204726A1 (en) 1976-02-27
DD110656A5 (en) 1975-01-05
AT330771B (en) 1976-07-26
ATA397875A (en) 1975-10-15
AU6452474A (en) 1975-07-17
AR201518A1 (en) 1975-03-21
CS184347B2 (en) 1978-08-31
ES422301A1 (en) 1976-07-01
IE38736L (en) 1974-07-17
LU69166A1 (en) 1975-12-09
IL44003A (en) 1977-05-31
FR2213771A1 (en) 1974-08-09
AR201704A1 (en) 1975-04-08
IE38736B1 (en) 1978-05-24
AR205618A1 (en) 1976-05-21
DE2400693A1 (en) 1974-07-18
IL44003A0 (en) 1974-05-16
AT330750B (en) 1976-07-12
AR204105A1 (en) 1975-11-20
SU520037A3 (en) 1976-06-30
BE809820A (en) 1974-07-16
HU168750B (en) 1976-07-28
DD113364A5 (en) 1975-06-05
ATA397675A (en) 1975-10-15
JPS49101343A (en) 1974-09-25

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee