GB1413629A - Process for the manufacture of delta 16- steroid- 14beta, 18, 20-triols and - 14beta, 20-diol-18-als of the pregnane series - Google Patents
Process for the manufacture of delta 16- steroid- 14beta, 18, 20-triols and - 14beta, 20-diol-18-als of the pregnane seriesInfo
- Publication number
- GB1413629A GB1413629A GB2565373A GB2565373A GB1413629A GB 1413629 A GB1413629 A GB 1413629A GB 2565373 A GB2565373 A GB 2565373A GB 2565373 A GB2565373 A GB 2565373A GB 1413629 A GB1413629 A GB 1413629A
- Authority
- GB
- United Kingdom
- Prior art keywords
- oxo
- methoxy
- pregnene
- oxido
- steroid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 150000003128 pregnanes Chemical class 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 150000002148 esters Chemical class 0.000 abstract 2
- 150000002170 ethers Chemical class 0.000 abstract 2
- 125000000524 functional group Chemical group 0.000 abstract 2
- HEWZVZIVELJPQZ-UHFFFAOYSA-N 2,2-dimethoxypropane Chemical compound COC(C)(C)OC HEWZVZIVELJPQZ-UHFFFAOYSA-N 0.000 abstract 1
- JWMFYGXQPXQEEM-NUNROCCHSA-N 5β-pregnane Chemical compound C([C@H]1CC2)CCC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H](CC)[C@@]2(C)CC1 JWMFYGXQPXQEEM-NUNROCCHSA-N 0.000 abstract 1
- ZKCSFQZJDZSMCH-IGLVISNFSA-N 962fmm1isf Chemical compound O1CCN(C)C[C@]23C([C@@H](O)C)=CC[C@]31C1=CC[C@H](C3)[C@]4(C)CC[C@@]3(O)O[C@@]41[C@H](O)C2 ZKCSFQZJDZSMCH-IGLVISNFSA-N 0.000 abstract 1
- 230000021736 acetylation Effects 0.000 abstract 1
- 238000006640 acetylation reaction Methods 0.000 abstract 1
- ZKCSFQZJDZSMCH-UHFFFAOYSA-N batrachotoxinin-A Natural products O1CCN(C)CC23C(C(O)C)=CCC31C1=CCC(C3)C4(C)CCC3(O)OC41C(O)C2 ZKCSFQZJDZSMCH-UHFFFAOYSA-N 0.000 abstract 1
- 150000002009 diols Chemical class 0.000 abstract 1
- 150000004678 hydrides Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 229910052987 metal hydride Inorganic materials 0.000 abstract 1
- 150000004681 metal hydrides Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000004048 modification Effects 0.000 abstract 1
- 238000012986 modification Methods 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 238000000926 separation method Methods 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- 150000004072 triols Chemical class 0.000 abstract 1
Landscapes
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH796672 | 1972-05-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1413629A true GB1413629A (en) | 1975-11-12 |
Family
ID=4333097
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2565373A Expired GB1413629A (en) | 1972-05-30 | 1973-05-30 | Process for the manufacture of delta 16- steroid- 14beta, 18, 20-triols and - 14beta, 20-diol-18-als of the pregnane series |
Country Status (4)
| Country | Link |
|---|---|
| JP (1) | JPS4961152A (enrdf_load_stackoverflow) |
| DE (1) | DE2325806A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2186466B1 (enrdf_load_stackoverflow) |
| GB (1) | GB1413629A (enrdf_load_stackoverflow) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE757924A (fr) * | 1969-10-24 | 1971-04-01 | Geigy Ag J R | Composes steroidiques a noyau heterocyclique azote, leur preparation etmedicaments contenant de tels composes |
| CH583253A5 (enrdf_load_stackoverflow) * | 1970-07-24 | 1976-12-31 | Ciba Geigy Ag | |
| DE2160522A1 (de) * | 1970-12-14 | 1972-06-29 | Ciba-Geigy Ag, Basel (Schweiz) | Verfahren zur Herstellung von 14 beta, 18- und 5 beta, 19-(Epoxyäthanoimino)steroiden |
-
1973
- 1973-05-22 DE DE19732325806 patent/DE2325806A1/de active Pending
- 1973-05-30 JP JP6142573A patent/JPS4961152A/ja active Pending
- 1973-05-30 GB GB2565373A patent/GB1413629A/en not_active Expired
- 1973-05-30 FR FR7319692A patent/FR2186466B1/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DE2325806A1 (de) | 1973-12-13 |
| FR2186466B1 (enrdf_load_stackoverflow) | 1977-07-29 |
| FR2186466A1 (enrdf_load_stackoverflow) | 1974-01-11 |
| JPS4961152A (enrdf_load_stackoverflow) | 1974-06-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |