GB1413472A - 2,4-diamino pyrimidines - Google Patents

2,4-diamino pyrimidines

Info

Publication number
GB1413472A
GB1413472A GB2688875A GB2688875A GB1413472A GB 1413472 A GB1413472 A GB 1413472A GB 2688875 A GB2688875 A GB 2688875A GB 2688875 A GB2688875 A GB 2688875A GB 1413472 A GB1413472 A GB 1413472A
Authority
GB
United Kingdom
Prior art keywords
diamino
prepared
carboxylic acid
organic sulphonic
sulphonic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2688875A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Priority to GB2688875A priority Critical patent/GB1413472A/en
Publication of GB1413472A publication Critical patent/GB1413472A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

1413472 2,4-Diamino-pyrimidines WELLCOME FOUNDATION Ltd 12 Oct 1972 [12 Oct 1971 10 Dec 1971] 26888/75 and 26894/75 Divided out of 1413471 Heading C2C The invention comprises compounds having the general formula wherein R<SP>7</SP> is the anionic residue of a carboxylic acid or an organic sulphonic acid. They may be prepared by reacting 2,4-diamino-5-hydroxymethyl pyrimidine with a carboxylic acid or an organic sulphonic acid, or by reacting 2,4- diamino - 5 - bromomethylpyrimidine with the sodium salt of a carboxylic acid or organic sulphonic acid. The 2,4-diamino-5-hydroxymethylpyrimidine starting material may be prepared by reduction of 2,4-diamino-5-formylpyrimidine which in turn may be prepared by reduction of 2,4-diamino-5-cyanopyrimidine.
GB2688875A 1971-10-12 1971-10-12 2,4-diamino pyrimidines Expired GB1413472A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB2688875A GB1413472A (en) 1971-10-12 1971-10-12 2,4-diamino pyrimidines

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB2688875A GB1413472A (en) 1971-10-12 1971-10-12 2,4-diamino pyrimidines
GB2689475 1971-12-10

Publications (1)

Publication Number Publication Date
GB1413472A true GB1413472A (en) 1975-11-12

Family

ID=26258488

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2688875A Expired GB1413472A (en) 1971-10-12 1971-10-12 2,4-diamino pyrimidines

Country Status (1)

Country Link
GB (1) GB1413472A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0006987A1 (en) * 1978-05-24 1980-01-23 The Wellcome Foundation Limited 2,4-Diamino-5-benzylpyrimidines, especially for the treatment of microbial infections, pharmaceutical compositions containing these compounds and processes for preparing these compounds

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0006987A1 (en) * 1978-05-24 1980-01-23 The Wellcome Foundation Limited 2,4-Diamino-5-benzylpyrimidines, especially for the treatment of microbial infections, pharmaceutical compositions containing these compounds and processes for preparing these compounds

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee