GB1412274A - Radioactive determination of serum thyroxine - Google Patents
Radioactive determination of serum thyroxineInfo
- Publication number
- GB1412274A GB1412274A GB4632972A GB1175874A GB1412274A GB 1412274 A GB1412274 A GB 1412274A GB 4632972 A GB4632972 A GB 4632972A GB 1175874 A GB1175874 A GB 1175874A GB 1412274 A GB1412274 A GB 1412274A
- Authority
- GB
- United Kingdom
- Prior art keywords
- serum
- thyroxine
- clay
- estimated
- bound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 210000002966 serum Anatomy 0.000 title abstract 5
- XUIIKFGFIJCVMT-GFCCVEGCSA-N D-thyroxine Chemical compound IC1=CC(C[C@@H](N)C(O)=O)=CC(I)=C1OC1=CC(I)=C(O)C(I)=C1 XUIIKFGFIJCVMT-GFCCVEGCSA-N 0.000 title abstract 4
- 229940034208 thyroxine Drugs 0.000 title abstract 3
- XUIIKFGFIJCVMT-UHFFFAOYSA-N thyroxine-binding globulin Natural products IC1=CC(CC([NH3+])C([O-])=O)=CC(I)=C1OC1=CC(I)=C(O)C(I)=C1 XUIIKFGFIJCVMT-UHFFFAOYSA-N 0.000 title abstract 3
- 230000002285 radioactive effect Effects 0.000 title abstract 2
- 239000004927 clay Substances 0.000 abstract 2
- 238000010828 elution Methods 0.000 abstract 2
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 abstract 1
- 102000009488 Thyroxine-Binding Proteins Human genes 0.000 abstract 1
- 108010048889 Thyroxine-Binding Proteins Proteins 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 238000005349 anion exchange Methods 0.000 abstract 1
- 150000001450 anions Chemical class 0.000 abstract 1
- 229910000278 bentonite Inorganic materials 0.000 abstract 1
- 239000000440 bentonite Substances 0.000 abstract 1
- SVPXDRXYRYOSEX-UHFFFAOYSA-N bentoquatam Chemical group O.O=[Si]=O.O=[Al]O[Al]=O SVPXDRXYRYOSEX-UHFFFAOYSA-N 0.000 abstract 1
- 230000027455 binding Effects 0.000 abstract 1
- 238000005341 cation exchange Methods 0.000 abstract 1
- 230000009137 competitive binding Effects 0.000 abstract 1
- GUJOJGAPFQRJSV-UHFFFAOYSA-N dialuminum;dioxosilane;oxygen(2-);hydrate Chemical compound O.[O-2].[O-2].[O-2].[Al+3].[Al+3].O=[Si]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O GUJOJGAPFQRJSV-UHFFFAOYSA-N 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000003456 ion exchange resin Substances 0.000 abstract 1
- 229920003303 ion-exchange polymer Polymers 0.000 abstract 1
- 150000002500 ions Chemical class 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 239000011347 resin Substances 0.000 abstract 1
- 229920005989 resin Polymers 0.000 abstract 1
- 238000000926 separation method Methods 0.000 abstract 1
- -1 styrene-divinyl benzene anion Chemical class 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
- G01N33/78—Thyroid gland hormones, e.g. T3, T4, TBH, TBG or their receptors
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/804—Radioisotope, e.g. radioimmunoassay
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/825—Pretreatment for removal of interfering factors from sample
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/364,564 US3947564A (en) | 1973-05-29 | 1973-05-29 | Radioactive determination of serum thyroxine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1412274A true GB1412274A (en) | 1975-11-05 |
Family
ID=23435060
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4632972A Expired GB1412274A (en) | 1973-05-29 | 1973-03-15 | Radioactive determination of serum thyroxine |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US3947564A (https=) |
| JP (1) | JPS5017697A (https=) |
| CA (1) | CA1003733A (https=) |
| DE (1) | DE2410755A1 (https=) |
| ES (1) | ES422273A1 (https=) |
| FR (1) | FR2231967B1 (https=) |
| GB (1) | GB1412274A (https=) |
| IT (1) | IT1008831B (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4070153A (en) * | 1975-03-28 | 1978-01-24 | Corning Glass Works | Preparation of serum standard for radioassay of thyroxine |
| US4311690A (en) * | 1978-06-20 | 1982-01-19 | Damon Corporation | Test set and method for the determination of free hormones |
| US4252782A (en) * | 1978-09-29 | 1981-02-24 | Meloy Laboratories, Inc. | Test for assessing the unsaturated binding capacity of serum proteins which bind thyroid hormones |
| US4255412A (en) * | 1978-12-19 | 1981-03-10 | Beckman Instruments, Inc. | T3 Uptake test employing a precipitated nylon separating agent |
| US5202006A (en) * | 1992-04-17 | 1993-04-13 | Beckman Instruments, Inc. | Analysis of hemoglobin variants by capillary zone electrophoresis |
| EP3256850B1 (en) | 2015-02-09 | 2025-07-09 | Slingshot Biosciences, Inc. | Hydrogel particles with tunable optical properties and methods for using the same |
| JP7759328B2 (ja) | 2020-01-24 | 2025-10-23 | スリングショット バイオサイエンシーズ， インコーポレイテッド | 細胞様較正粒子のための組成物および方法 |
| CA3177834A1 (en) | 2020-05-04 | 2021-11-11 | Jeffrey Kim | Compositions and methods for passive optical barcoding for multiplexed assays |
| JP2024539956A (ja) | 2021-10-29 | 2024-10-31 | スリングショット バイオサイエンシーズ， インコーポレイテッド | フィーダー細胞としておよび合成抗原提示細胞としてのヒドロゲル粒子 |
| CN119907921A (zh) | 2022-05-05 | 2025-04-29 | 弹弓生物科学公司 | 用于血液学的作为红细胞模拟物的工程化颗粒和含有工程化颗粒的组合物 |
| AU2023280490A1 (en) | 2022-06-02 | 2024-12-05 | Slingshot Biosciences, Inc. | Apoptotic cell mimic |
| EP4608872A2 (en) | 2022-10-26 | 2025-09-03 | Slingshot Biosciences, Inc. | Size-tunable synthetic particles with tunable optical properties and methods for using the same for immune cell activation |
| WO2025049609A1 (en) | 2023-08-29 | 2025-03-06 | Slingshot Biosciences, Inc. | Cd34 stem cell mimics |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3414383A (en) * | 1965-08-09 | 1968-12-03 | Canadian Patents Dev | Determination of thyroxine |
| US3451777A (en) * | 1965-08-20 | 1969-06-24 | Walter Di Giulio | Method and apparatus for determining the thyroid hormone content of blood |
| US3714344A (en) * | 1969-05-01 | 1973-01-30 | Mallinckrodt Chemical Works | Method for determining thyroxine in blood serum and reagent therefor |
| US3555001A (en) * | 1969-05-29 | 1971-01-12 | Monsanto Co | Process for the fractionation of plasma and serum using water-insoluble polyelectrolytes containing diloweralkylaminoloweralkylimide groups |
| US3666854A (en) * | 1969-07-30 | 1972-05-30 | Nuclear Med Lab | Test for thyroid hormone |
| US3659104A (en) * | 1970-06-29 | 1972-04-25 | Univ Jerusalem The | Method of measuring serum thyroxine |
| US3776698A (en) * | 1972-01-24 | 1973-12-04 | Nuclear Med Lab | Test for thyroid hormone |
-
1973
- 1973-03-15 GB GB4632972A patent/GB1412274A/en not_active Expired
- 1973-05-29 US US05/364,564 patent/US3947564A/en not_active Expired - Lifetime
-
1974
- 1974-01-11 JP JP49006110A patent/JPS5017697A/ja active Pending
- 1974-01-14 ES ES422273A patent/ES422273A1/es not_active Expired
- 1974-01-25 CA CA190,928A patent/CA1003733A/en not_active Expired
- 1974-02-06 FR FR7404010A patent/FR2231967B1/fr not_active Expired
- 1974-02-13 IT IT48278/74A patent/IT1008831B/it active
- 1974-03-06 DE DE2410755A patent/DE2410755A1/de active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US3947564A (en) | 1976-03-30 |
| JPS5017697A (https=) | 1975-02-25 |
| FR2231967A1 (https=) | 1974-12-27 |
| IT1008831B (it) | 1976-11-30 |
| CA1003733A (en) | 1977-01-18 |
| FR2231967B1 (https=) | 1978-09-08 |
| ES422273A1 (es) | 1976-06-16 |
| DE2410755A1 (de) | 1975-01-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |