GB1411661A - Method of preparing antiserum for serological identification of pathogenic species of candida - Google Patents

Method of preparing antiserum for serological identification of pathogenic species of candida

Info

Publication number
GB1411661A
GB1411661A GB1477873A GB1477873A GB1411661A GB 1411661 A GB1411661 A GB 1411661A GB 1477873 A GB1477873 A GB 1477873A GB 1477873 A GB1477873 A GB 1477873A GB 1411661 A GB1411661 A GB 1411661A
Authority
GB
United Kingdom
Prior art keywords
yeast
candida
mannan
complex
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1477873A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Co Inc
Original Assignee
Ajinomoto Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Co Inc filed Critical Ajinomoto Co Inc
Publication of GB1411661A publication Critical patent/GB1411661A/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0002Fungal antigens, e.g. Trichophyton, Aspergillus, Candida
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56961Plant cells or fungi

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Food Science & Technology (AREA)
  • Botany (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

1411661 Candida antiserum AJINOMOTO CO Inc 27 March 1973 [4 July 1972] 14778/73 Heading A5B An anti-serum for serological identification of pathogenic species of Candida is prepared by (a) separating cell wall mannan from a yeast having at least one antigen factor in common with Candida albicans, (b) bonding said mannan to a carrier protein alien to yeasts to produce a haptan-carrier complex, said mannan constituting the hapten in said complex, (c) parenterally administering said complex to a warm-blooded animal in an amount sufficient to induce an anti-serum which contains antibodies specific to said yeast in the blood of the animal and (d) harvesting said blood. The yeast may be C. albicans, C. tropicalis, C. pseudotropicalis, Kluyveromyces fragilis, C. guilliermondi, C. parakrusei, Metschnikowia pulcherrima, Pichia fermentans or Toruopsis glabrata.The protein may be bovine gamma-globulin. The mannan may be bonded to the protein by reaction with a polychlorinated triazine or with bromoacetyl bromide. The hapten-protein complex may be administered intravenously to a rabbit. The fibrinogen and corpuscles may be removed from the harvested blood to produce the antiserum. Some of the antibody factors may be removed from the antiserum by treatment with a yeast.
GB1477873A 1972-07-04 1973-03-27 Method of preparing antiserum for serological identification of pathogenic species of candida Expired GB1411661A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP6638972A JPS516729B2 (en) 1972-07-04 1972-07-04

Publications (1)

Publication Number Publication Date
GB1411661A true GB1411661A (en) 1975-10-29

Family

ID=13314408

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1477873A Expired GB1411661A (en) 1972-07-04 1973-03-27 Method of preparing antiserum for serological identification of pathogenic species of candida

Country Status (6)

Country Link
JP (1) JPS516729B2 (en)
CH (1) CH564352A5 (en)
DE (1) DE2308037A1 (en)
FR (1) FR2190424B1 (en)
GB (1) GB1411661A (en)
NL (1) NL7302127A (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU547928B2 (en) * 1981-11-03 1985-11-14 Sutka, K. Antigenic preparation from candida guilliermondii
FR2598513B1 (en) * 1986-02-06 1991-12-13 Chemunex NOVEL ANTIBODY ANTIBODIES CAPABLE OF RECOGNIZING MULTIPLE YEASTS, HYBRID CELL LINES PRODUCING SUCH ANTIBODIES, THEIR PREPARATION AND THEIR USES AND APPLICATIONS IN DETECTION AND POSSIBLY IN YEAST NUMBERING
FR2680519B1 (en) * 1991-08-22 1993-11-05 Diagnostica Stago PROCESS FOR HIGHLIGHTING THE AFFINITY OF FIBRINOGEN AND ITS DERIVATIVES IN FILAMENTARY FORMS OF YEASTS, USE IN THE FIELD OF DETERMINING PATHOGENIC YEASTS, PARTICULARLY IN HEMOCULTURE.

Also Published As

Publication number Publication date
FR2190424B1 (en) 1977-12-30
DE2308037A1 (en) 1974-01-24
NL7302127A (en) 1974-01-08
JPS516729B2 (en) 1976-03-02
CH564352A5 (en) 1975-07-31
JPS4926418A (en) 1974-03-08
FR2190424A1 (en) 1974-02-01

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee