GB1410011A - Ethylene diamine derivatives - Google Patents
Ethylene diamine derivativesInfo
- Publication number
- GB1410011A GB1410011A GB756771A GB756771A GB1410011A GB 1410011 A GB1410011 A GB 1410011A GB 756771 A GB756771 A GB 756771A GB 756771 A GB756771 A GB 756771A GB 1410011 A GB1410011 A GB 1410011A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- methyl
- dihydrochloride
- dimethylamino
- methylpropylamine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000003916 ethylene diamine group Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 6
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- PIICEJLVQHRZGT-UHFFFAOYSA-N Ethylenediamine Chemical class NCCN PIICEJLVQHRZGT-UHFFFAOYSA-N 0.000 abstract 2
- -1 N,N,1,1 - tetramethyl - 2 - iminopropylamine N - methyl - 2 - dimethylamino - 2 - methylpropylamine dihydrochloride Chemical compound 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- PAFZNILMFXTMIY-UHFFFAOYSA-N cyclohexylamine Chemical compound NC1CCCCC1 PAFZNILMFXTMIY-UHFFFAOYSA-N 0.000 abstract 2
- 125000004817 pentamethylene group Chemical group [H]C([H])([*:2])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[*:1] 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- OHGRMGNDTSKKJV-UHFFFAOYSA-N (1-piperidin-1-ylcyclohexyl)methanamine Chemical compound C1CCCCN1C1(CN)CCCCC1 OHGRMGNDTSKKJV-UHFFFAOYSA-N 0.000 abstract 1
- OBZUGXDFZLYGQH-UHFFFAOYSA-N 1-(aminomethyl)-n-benzyl-n-methylcyclohexan-1-amine Chemical compound C1CCCCC1(CN)N(C)CC1=CC=CC=C1 OBZUGXDFZLYGQH-UHFFFAOYSA-N 0.000 abstract 1
- SDHHZJUUIBWPPN-UHFFFAOYSA-N 1-(dimethylamino)cyclohexane-1-carbonitrile Chemical compound CN(C)C1(C#N)CCCCC1 SDHHZJUUIBWPPN-UHFFFAOYSA-N 0.000 abstract 1
- LLAPDLPYIYKTGQ-UHFFFAOYSA-N 1-aminoethyl Chemical group C[CH]N LLAPDLPYIYKTGQ-UHFFFAOYSA-N 0.000 abstract 1
- IJWNLEIIHFCXQS-UHFFFAOYSA-N 1-n,2-n,2-n,2-tetramethylhexane-1,2-diamine Chemical compound CCCCC(C)(N(C)C)CNC IJWNLEIIHFCXQS-UHFFFAOYSA-N 0.000 abstract 1
- WWSAYKJWUZJLRT-UHFFFAOYSA-N 1-piperidinocyclohexanecarbonitrile Chemical compound C1CCCCN1C1(C#N)CCCCC1 WWSAYKJWUZJLRT-UHFFFAOYSA-N 0.000 abstract 1
- MUEYPOABQOGIKY-UHFFFAOYSA-N 2-(dimethylamino)-2-methylhexanenitrile Chemical compound CCCCC(C)(C#N)N(C)C MUEYPOABQOGIKY-UHFFFAOYSA-N 0.000 abstract 1
- QUCPOOYBUZPGBF-UHFFFAOYSA-N 2-N,2-N,2-trimethylbutane-2,3-diamine dihydrochloride Chemical compound Cl.Cl.CC(N)C(C)(C)N(C)C QUCPOOYBUZPGBF-UHFFFAOYSA-N 0.000 abstract 1
- LMCRHECKICWWOP-UHFFFAOYSA-N 2-methyl-2-N-(2-phenylethyl)butane-2,3-diamine Chemical compound CC(N)C(C)(C)NCCC1=CC=CC=C1 LMCRHECKICWWOP-UHFFFAOYSA-N 0.000 abstract 1
- SSORUHAKVDLSAD-UHFFFAOYSA-N 2-methyl-2-n-(2-phenylethyl)propane-1,2-diamine Chemical compound NCC(C)(C)NCCC1=CC=CC=C1 SSORUHAKVDLSAD-UHFFFAOYSA-N 0.000 abstract 1
- KDYNEXUMMFHRKY-UHFFFAOYSA-N 2-n,2-n,2-trimethylhexane-1,2-diamine Chemical compound CCCCC(C)(CN)N(C)C KDYNEXUMMFHRKY-UHFFFAOYSA-N 0.000 abstract 1
- 125000000882 C2-C6 alkenyl group Chemical group 0.000 abstract 1
- 125000003601 C2-C6 alkynyl group Chemical group 0.000 abstract 1
- STZNQAFCYSOUIE-UHFFFAOYSA-N Cl.Cl.CN(C(CN)(C)C)C.CN(C(C(=O)N)(C)C)C Chemical compound Cl.Cl.CN(C(CN)(C)C)C.CN(C(C(=O)N)(C)C)C STZNQAFCYSOUIE-UHFFFAOYSA-N 0.000 abstract 1
- JVUTULSYUBFRCR-UHFFFAOYSA-N [1-(4-methylpiperazin-1-yl)cyclohexyl]methanamine Chemical compound C1CN(C)CCN1C1(CN)CCCCC1 JVUTULSYUBFRCR-UHFFFAOYSA-N 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 230000002152 alkylating effect Effects 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 125000004202 aminomethyl group Chemical group [H]N([H])C([H])([H])* 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 125000001316 cycloalkyl alkyl group Chemical group 0.000 abstract 1
- 125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 abstract 1
- KDSNLYIMUZNERS-UHFFFAOYSA-N isobutyl amine Natural products CC(C)CN KDSNLYIMUZNERS-UHFFFAOYSA-N 0.000 abstract 1
- 125000006533 methyl amino methyl group Chemical group [H]N(C([H])([H])[H])C([H])([H])* 0.000 abstract 1
- HHGZTIZUMKCUGM-UHFFFAOYSA-N n-methyl-1-[1-(4-methylpiperazin-1-yl)cyclohexyl]methanamine Chemical compound C1CN(C)CCN1C1(CNC)CCCCC1 HHGZTIZUMKCUGM-UHFFFAOYSA-N 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- OHEDMAIVEXQCOZ-UHFFFAOYSA-N piperidine;dihydrochloride Chemical compound Cl.Cl.C1CCNCC1 OHEDMAIVEXQCOZ-UHFFFAOYSA-N 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/20—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by nitrogen atoms not being part of nitro or nitroso groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BE789025D BE789025A (fr) | 1971-09-23 | Nouvelles ethylene diamines substituees | |
| GB756771A GB1410011A (en) | 1971-09-23 | 1971-09-23 | Ethylene diamine derivatives |
| ZA726282A ZA726282B (en) | 1971-09-23 | 1972-09-14 | Ethylene diamine derivatives |
| CA152,009A CA995220A (en) | 1971-09-23 | 1972-09-15 | Ethylene diamine derivatives |
| AU46798/72A AU475627B2 (en) | 1971-09-23 | 1972-09-18 | Ethylene diamine derivatives |
| IL40397A IL40397A (en) | 1971-09-23 | 1972-09-20 | Ethylene diamine derivatives their production and pharmaceutical compositions containing them |
| JP47095039A JPS4839409A (enrdf_load_stackoverflow) | 1971-09-23 | 1972-09-21 | |
| DE19722246728 DE2246728A1 (de) | 1971-09-23 | 1972-09-22 | Neue substituierte aethylendiamine, verfahren zu ihrer herstellung und solche diamine enthaltende arzneipraeparate |
| FR7233698A FR2154559B1 (enrdf_load_stackoverflow) | 1971-09-23 | 1972-09-22 | |
| CH1388472A CH597153A5 (enrdf_load_stackoverflow) | 1971-09-23 | 1972-09-22 | |
| NL7212967A NL7212967A (enrdf_load_stackoverflow) | 1971-09-23 | 1972-09-25 |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB756771A GB1410011A (en) | 1971-09-23 | 1971-09-23 | Ethylene diamine derivatives |
| GB2624872 | 1972-06-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1410011A true GB1410011A (en) | 1975-10-15 |
Family
ID=26241518
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB756771A Expired GB1410011A (en) | 1971-09-23 | 1971-09-23 | Ethylene diamine derivatives |
Country Status (9)
| Country | Link |
|---|---|
| JP (1) | JPS4839409A (enrdf_load_stackoverflow) |
| BE (1) | BE789025A (enrdf_load_stackoverflow) |
| CA (1) | CA995220A (enrdf_load_stackoverflow) |
| CH (1) | CH597153A5 (enrdf_load_stackoverflow) |
| DE (1) | DE2246728A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2154559B1 (enrdf_load_stackoverflow) |
| GB (1) | GB1410011A (enrdf_load_stackoverflow) |
| IL (1) | IL40397A (enrdf_load_stackoverflow) |
| NL (1) | NL7212967A (enrdf_load_stackoverflow) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006067414A3 (en) * | 2004-12-23 | 2006-09-08 | Glaxo Group Ltd | Glycine transport inhibitors |
| US7745642B2 (en) | 2004-12-23 | 2010-06-29 | Glaxo Group Limited | Glycine transport inhibitors |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5319654B2 (enrdf_load_stackoverflow) | 1974-03-14 | 1978-06-22 | ||
| JPS5547977Y2 (enrdf_load_stackoverflow) * | 1975-07-18 | 1980-11-10 | ||
| JPS5253328A (en) * | 1975-10-27 | 1977-04-28 | Mazda Motor Corp | Engine rotation control of car having power steering |
| JPH0723348B2 (ja) * | 1986-08-27 | 1995-03-15 | 花王株式会社 | 新規なアシル化エチレンジアミン誘導体とその製造方法および用途 |
| CN1495160A (zh) * | 1997-12-16 | 2004-05-12 | ��ʲ | 1-取代-1-氨基甲基-环烷衍生物（＝加巴喷丁类似物）、其制备及其在治疗神经病方面的用途 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2692265A (en) * | 1951-01-23 | 1954-10-19 | American Home Prod | Substituted glycinamides |
| US2993068A (en) * | 1958-07-01 | 1961-07-18 | Ethicon Inc | 1-aminomethyl-1-aminocyclohexanes |
| CH397684A (fr) * | 1961-05-02 | 1965-08-31 | Kuhlmann Ets | Procédé de la préparation de la pyrrolidide de l'acide triméthoxy-3',4',5' benzoylamino-acétique |
| US3258489A (en) * | 1963-06-14 | 1966-06-28 | Monsanto Co | N-(1-aminocyclohexylmethyl)anilines and n-(1-nitrocyclohexylmethyl)an-ilines |
| GB1058002A (en) * | 1964-07-07 | 1967-02-08 | Farmochimica Cutolo Calosi S P | Aryl-amino-acylamides |
| SE337810B (enrdf_load_stackoverflow) * | 1966-05-13 | 1971-08-23 | Tanabe Seiyaku Co | |
| AT273969B (de) * | 1966-08-01 | 1969-09-10 | Miles Lab | Verfahren zur Herstellung von neuen N-Aminoalkyl-N-benzylamiden und ihrer Salze |
| US3510492A (en) * | 1968-05-13 | 1970-05-05 | Upjohn Co | 2-anilino and 2-anilinomethyl cycloalkylamines |
-
0
- BE BE789025D patent/BE789025A/xx unknown
-
1971
- 1971-09-23 GB GB756771A patent/GB1410011A/en not_active Expired
-
1972
- 1972-09-15 CA CA152,009A patent/CA995220A/en not_active Expired
- 1972-09-20 IL IL40397A patent/IL40397A/en unknown
- 1972-09-21 JP JP47095039A patent/JPS4839409A/ja active Pending
- 1972-09-22 CH CH1388472A patent/CH597153A5/xx not_active IP Right Cessation
- 1972-09-22 FR FR7233698A patent/FR2154559B1/fr not_active Expired
- 1972-09-22 DE DE19722246728 patent/DE2246728A1/de active Pending
- 1972-09-25 NL NL7212967A patent/NL7212967A/xx not_active Application Discontinuation
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006067414A3 (en) * | 2004-12-23 | 2006-09-08 | Glaxo Group Ltd | Glycine transport inhibitors |
| US7745642B2 (en) | 2004-12-23 | 2010-06-29 | Glaxo Group Limited | Glycine transport inhibitors |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2154559A1 (enrdf_load_stackoverflow) | 1973-05-11 |
| CA995220A (en) | 1976-08-17 |
| NL7212967A (enrdf_load_stackoverflow) | 1973-03-27 |
| DE2246728A1 (de) | 1973-05-03 |
| JPS4839409A (enrdf_load_stackoverflow) | 1973-06-09 |
| BE789025A (fr) | 1973-03-20 |
| CH597153A5 (enrdf_load_stackoverflow) | 1978-03-31 |
| FR2154559B1 (enrdf_load_stackoverflow) | 1976-08-20 |
| IL40397A (en) | 1977-06-30 |
| IL40397A0 (en) | 1972-11-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |