GB1407304A - Substitued prostaglandin derivatives - Google Patents

Substitued prostaglandin derivatives

Info

Publication number
GB1407304A
GB1407304A GB5499472A GB5499472A GB1407304A GB 1407304 A GB1407304 A GB 1407304A GB 5499472 A GB5499472 A GB 5499472A GB 5499472 A GB5499472 A GB 5499472A GB 1407304 A GB1407304 A GB 1407304A
Authority
GB
United Kingdom
Prior art keywords
substitued
prostaglandin derivatives
prostaglandin
derivatives
substitued prostaglandin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB5499472A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Palo Alto LLC
Original Assignee
Roche Palo Alto LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Palo Alto LLC filed Critical Roche Palo Alto LLC
Publication of GB1407304A publication Critical patent/GB1407304A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0016—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing only hydroxy, etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/516—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of nitrogen-containing compounds to >C = O groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/753—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
GB5499472A 1971-12-03 1972-11-28 Substitued prostaglandin derivatives Expired GB1407304A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US00204681A US3846475A (en) 1971-12-03 1971-12-03 10-hydroxy pge{11 {11 and pge {11

Publications (1)

Publication Number Publication Date
GB1407304A true GB1407304A (en) 1975-09-24

Family

ID=22758980

Family Applications (1)

Application Number Title Priority Date Filing Date
GB5499472A Expired GB1407304A (en) 1971-12-03 1972-11-28 Substitued prostaglandin derivatives

Country Status (3)

Country Link
US (1) US3846475A (enExample)
FR (1) FR2162212B1 (enExample)
GB (1) GB1407304A (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3931297A (en) * 1971-12-03 1976-01-06 Syntex (U.S.A.) Inc. 10-Hydroxy PGC compounds
US3933890A (en) * 1972-02-18 1976-01-20 May & Baker Limited 10,11,15-Trihydroxyprostanoic acid
US4052407A (en) * 1974-05-14 1977-10-04 Gyogyszerkutato Intezet Thiazole derivatives and processes for preparing the same
GB1510476A (en) * 1975-06-11 1978-05-10 Ici Ltd Stereoselective chemical reduction process for prostaglandin intermediates
US4188329A (en) * 1975-09-08 1980-02-12 Abbott Laboratories Intermediates for the preparation of prostaglandins and prostaglandin analogs from a mold metabolite
US4204999A (en) * 1976-02-20 1980-05-27 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt. Process for making bicyclic lactone derivatives for use as intermediates in the synthesis of prostaglandins
GB1538201A (en) * 1976-08-11 1979-01-10 Ici Ltd Prostane derivatives
JPS5365854A (en) * 1976-11-24 1978-06-12 May & Baker Ltd New preparation of cyclopentane derivative
US4100192A (en) * 1977-04-18 1978-07-11 The Upjohn Company Inter-phenylene-PG amides
US4110532A (en) * 1977-07-14 1978-08-29 The Upjohn Company 5-Hydroxy-PGI1 compounds
US4170703A (en) * 1977-07-14 1979-10-09 The Upjohn Company 5-Hydroxy-PGI1 morpholinylamides
US4166903A (en) * 1977-07-14 1979-09-04 The Upjohn Company 5-Hydroxy-PGI1 pyrrolidylamides
US4167624A (en) * 1977-07-14 1979-09-11 The Upjohn Company 5-Hydroxy-PGI1 pyrrolinylamides

Also Published As

Publication number Publication date
FR2162212A1 (enExample) 1973-07-13
FR2162212B1 (enExample) 1975-10-31
US3846475A (en) 1974-11-05

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PLNP Patent lapsed through nonpayment of renewal fees