GB1400464A - Biocidal salts - Google Patents

Biocidal salts

Info

Publication number
GB1400464A
GB1400464A GB2631872A GB2631872A GB1400464A GB 1400464 A GB1400464 A GB 1400464A GB 2631872 A GB2631872 A GB 2631872A GB 2631872 A GB2631872 A GB 2631872A GB 1400464 A GB1400464 A GB 1400464A
Authority
GB
United Kingdom
Prior art keywords
polymyxin
penicillin
antibiotic
cephalosporin
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2631872A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sutures Inc
Original Assignee
Sutures Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sutures Inc filed Critical Sutures Inc
Publication of GB1400464A publication Critical patent/GB1400464A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • C07H15/236—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2 a saccharide radical being substituted by an alkylamino radical in position 3 and by two substituents different from hydrogen in position 4, e.g. gentamicin complex, sisomicin, verdamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/60—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation occurring through the 4-amino group of 2,4-diamino-butanoic acid
    • C07K7/62—Polymyxins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)

Abstract

1400464 Antibiotic peptides SUTURES Inc 6 June 1972 [25 April 1972] 26318/72 Heading C3H [Also in Divisions A5 and C2] Novel antibiotically active salts of (i) an acidic penicillin or cephalosporin with (ii) a basic polymyxin or gentamicin are prepared by mixing together an aqueous solution containing the penicillin or cephalosporin and an aqueous solution containing the polymyxin or gentamicin to precipitate the substantially waterinsoluble salt, which is then separated from the aqueous mixture and dried. The penicillin may be Penicillin G, N, O or V, nafcillin, oxacillin or methicillin. Suitable cephalosporin antibioitcs are cephaloxin, cephaloglycin, cephaloridine and cephalothin. The polymyxin is Polymyxin B. The aqueous solutions are made up from the acidic antibiotic or preferably its Na or K salt, and a mineral acid addition salt of the basic antibiotic. The antibiotic salts are incorporated by impregnation or by precipitation in situ into bandages and other textile substrates for medical use.
GB2631872A 1972-04-25 1972-06-06 Biocidal salts Expired GB1400464A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US24746672A 1972-04-25 1972-04-25

Publications (1)

Publication Number Publication Date
GB1400464A true GB1400464A (en) 1975-07-16

Family

ID=22935052

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2631872A Expired GB1400464A (en) 1972-04-25 1972-06-06 Biocidal salts

Country Status (7)

Country Link
JP (1) JPS4920317A (en)
CA (1) CA950831A (en)
CH (1) CH553815A (en)
DE (1) DE2301633A1 (en)
FR (1) FR2186230B1 (en)
GB (1) GB1400464A (en)
ZA (1) ZA723917B (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997026886A1 (en) * 1996-01-25 1997-07-31 Pharmacy And Therapeutic Advisory Consultancy Pty. Ltd Methods of and compositions for potentiating the action of agents active on cell wall sites of the susceptible bacteria
EP1287818A1 (en) * 2001-08-31 2003-03-05 Heraeus Kulzer GmbH & Co.KG Methods of antibiotic coating of objects having interconnected microcavities and the uses thereof
US7358232B2 (en) 2001-08-31 2008-04-15 Heraeus Kulzer Gmbh & Co.Kg Method for the antibiotic coating of bodies with interconnecting microcavities as well as coated bodies and their usage
WO2017019943A1 (en) * 2015-07-29 2017-02-02 Susanne Gardner Antimicrobial formulations and applications thereof
US10682360B2 (en) 2014-01-27 2020-06-16 Susanne GARDNER Antimicrobial formulations and applications thereof

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0115001B1 (en) * 1982-12-28 1988-06-15 Bayer Ag Stable aminoglycoside-penicillin injection formulation
SK3999A3 (en) * 1996-07-16 1999-07-12 Gist Brocades Nv 'beta'-lactam granules free of organic solvents
DE10262176B4 (en) 2002-06-21 2007-10-04 Heraeus Kulzer Gmbh Process for the preparation of antibiotically coated porous bodies and use
CN103349659A (en) 2006-09-26 2013-10-16 塔罗制药北美有限公司 Liquid compositions and application

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997026886A1 (en) * 1996-01-25 1997-07-31 Pharmacy And Therapeutic Advisory Consultancy Pty. Ltd Methods of and compositions for potentiating the action of agents active on cell wall sites of the susceptible bacteria
US6475992B2 (en) 1996-01-25 2002-11-05 Pharmacy And Therapeutic Advisory Consultancy Pty Ltd Methods of and compositions for potentiating the action of agents active on cell wall sites of the susceptible bacteria
EP1287818A1 (en) * 2001-08-31 2003-03-05 Heraeus Kulzer GmbH & Co.KG Methods of antibiotic coating of objects having interconnected microcavities and the uses thereof
US6984410B2 (en) 2001-08-31 2006-01-10 Heraeus Kulzer Gmbh & Co. Kg Process for antibiotic coating of elements with interconnecting microcavities, elements thus coated as well as their usage
US7358232B2 (en) 2001-08-31 2008-04-15 Heraeus Kulzer Gmbh & Co.Kg Method for the antibiotic coating of bodies with interconnecting microcavities as well as coated bodies and their usage
US10682360B2 (en) 2014-01-27 2020-06-16 Susanne GARDNER Antimicrobial formulations and applications thereof
WO2017019943A1 (en) * 2015-07-29 2017-02-02 Susanne Gardner Antimicrobial formulations and applications thereof

Also Published As

Publication number Publication date
CH553815A (en) 1974-09-13
DE2301633A1 (en) 1973-11-08
FR2186230B1 (en) 1976-07-02
CA950831A (en) 1974-07-09
ZA723917B (en) 1973-07-25
JPS4920317A (en) 1974-02-22
FR2186230A1 (en) 1974-01-11

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Legal Events

Date Code Title Description
PS Patent sealed
732 Registration of transactions, instruments or events in the register (sect. 32/1977)
PCNP Patent ceased through non-payment of renewal fee