GB1390486A - Pyrones - Google Patents
PyronesInfo
- Publication number
- GB1390486A GB1390486A GB2047673A GB2047673A GB1390486A GB 1390486 A GB1390486 A GB 1390486A GB 2047673 A GB2047673 A GB 2047673A GB 2047673 A GB2047673 A GB 2047673A GB 1390486 A GB1390486 A GB 1390486A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- pyrones
- dohme
- indolyl
- hydroxyalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/34—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D309/36—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
- C07D309/40—Oxygen atoms attached in positions 3 and 4, e.g. maltol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
- Saccharide Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
1390486 Pyrones MERCK SHARP & DOHME (IA) CORP 30 April 1973 [5 May 1972] 20476/73 Heading C2C #-Pyrones are prepared by the following route (R = C 1-3 alkyl, Ph-(C 1-3 alkyl); R<SP>1</SP> = 3-6 alkyl, hydroxyalkyl or alkynyl, Ph-(C 1-6 alkyl), indolyl-(C 1-6 alkyl)), optionally followed by salt formation. The products are #-adrenergic blocking agents, and may be administered in the form of pharmaceutical preparations containing them in association with a carrier.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA141,469A CA989848A (en) | 1972-05-05 | 1972-05-05 | 3-(3-substituted amino-2-hydroxypropoxy)-2-substituted-4-pyranones and process for preparing |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1390486A true GB1390486A (en) | 1975-04-16 |
Family
ID=4093187
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2047673A Expired GB1390486A (en) | 1972-05-05 | 1973-04-30 | Pyrones |
Country Status (13)
| Country | Link |
|---|---|
| JP (1) | JPS5635185B2 (en) |
| AU (1) | AU473061B2 (en) |
| BE (1) | BE799097A (en) |
| CA (1) | CA989848A (en) |
| CH (1) | CH577989A5 (en) |
| DE (1) | DE2322361A1 (en) |
| ES (1) | ES414319A1 (en) |
| FR (1) | FR2183750B1 (en) |
| GB (1) | GB1390486A (en) |
| HU (1) | HU165584B (en) |
| NL (1) | NL7305478A (en) |
| SE (1) | SE396605B (en) |
| ZA (1) | ZA733050B (en) |
-
1972
- 1972-05-05 CA CA141,469A patent/CA989848A/en not_active Expired
-
1973
- 1973-04-16 SE SE7305382A patent/SE396605B/en unknown
- 1973-04-18 NL NL7305478A patent/NL7305478A/xx not_active Application Discontinuation
- 1973-04-27 AU AU54938/73A patent/AU473061B2/en not_active Expired
- 1973-04-30 GB GB2047673A patent/GB1390486A/en not_active Expired
- 1973-05-03 DE DE2322361A patent/DE2322361A1/en not_active Withdrawn
- 1973-05-03 ES ES414319A patent/ES414319A1/en not_active Expired
- 1973-05-03 FR FR7315860A patent/FR2183750B1/fr not_active Expired
- 1973-05-04 BE BE130744A patent/BE799097A/en unknown
- 1973-05-04 HU HUME1625A patent/HU165584B/hu unknown
- 1973-05-04 CH CH636873A patent/CH577989A5/xx not_active IP Right Cessation
- 1973-05-04 ZA ZA733050A patent/ZA733050B/en unknown
- 1973-05-07 JP JP4989173A patent/JPS5635185B2/ja not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| CH577989A5 (en) | 1976-07-30 |
| JPS4961167A (en) | 1974-06-13 |
| DE2322361A1 (en) | 1973-11-22 |
| ES414319A1 (en) | 1976-02-01 |
| FR2183750A1 (en) | 1973-12-21 |
| CA989848A (en) | 1976-05-25 |
| FR2183750B1 (en) | 1976-03-05 |
| AU5493873A (en) | 1974-10-31 |
| NL7305478A (en) | 1973-11-07 |
| ZA733050B (en) | 1974-12-24 |
| HU165584B (en) | 1974-09-28 |
| SE396605B (en) | 1977-09-26 |
| JPS5635185B2 (en) | 1981-08-15 |
| AU473061B2 (en) | 1976-06-10 |
| BE799097A (en) | 1973-11-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |