GB1381588A - Process for the preparation of porous tablets - Google Patents

Process for the preparation of porous tablets

Info

Publication number
GB1381588A
GB1381588A GB4318773A GB4318773A GB1381588A GB 1381588 A GB1381588 A GB 1381588A GB 4318773 A GB4318773 A GB 4318773A GB 4318773 A GB4318773 A GB 4318773A GB 1381588 A GB1381588 A GB 1381588A
Authority
GB
United Kingdom
Prior art keywords
tablets
adjuvant
preparation
sept
porous tablets
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB4318773A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Publication of GB1381588A publication Critical patent/GB1381588A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S516/00—Colloid systems and wetting agents; subcombinations thereof; processes of
    • Y10S516/01—Wetting, emulsifying, dispersing, or stabilizing agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)

Abstract

1381588 Preparation of porous tablets BOEHRINGER MANNHEIM GmbH 14 Sept 1973 [20 Sept 1972] 43187/73 Heading A5B Porous tablets are prepared by hard-pressing the tablet components together with at least one inert solid adjuvant which sublimes at a temperature which does not adversely affect any of the tablet components and then subliming the adjuvant preferably in a vacuum. The adjuvant may be urethane, urea, ammonium carbonate, ammonium bicarbonate, hexamethylene-tetramine, benzoic acid, phthalic anhydride, naphthalene or camphor. The tablets may contain conventional water-soluble carrier materials for example sodium chloride, potassium chloride, borax, phosphates, oligosaccharides, polyethylene glycols and tensides.
GB4318773A 1972-09-20 1973-09-14 Process for the preparation of porous tablets Expired GB1381588A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2246013A DE2246013A1 (en) 1972-09-20 1972-09-20 PROCESS FOR THE MANUFACTURING OF POROUS TABLETS

Publications (1)

Publication Number Publication Date
GB1381588A true GB1381588A (en) 1975-01-22

Family

ID=5856791

Family Applications (1)

Application Number Title Priority Date Filing Date
GB4318773A Expired GB1381588A (en) 1972-09-20 1973-09-14 Process for the preparation of porous tablets

Country Status (9)

Country Link
US (1) US3885026A (en)
JP (1) JPS4969819A (en)
AT (1) AT324568B (en)
CH (1) CH579394A5 (en)
DE (1) DE2246013A1 (en)
FR (1) FR2199973B1 (en)
GB (1) GB1381588A (en)
IT (1) IT998618B (en)
SE (1) SE395366B (en)

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5762961A (en) * 1996-02-09 1998-06-09 Quadrant Holdings Cambridge Ltd. Rapidly soluble oral solid dosage forms, methods of making same, and compositions thereof
US5958455A (en) * 1996-02-09 1999-09-28 Quadrant Holdings Cambridge Ltd Oral solid dosage forms, methods of making same and compositions thereof
US6290991B1 (en) 1994-12-02 2001-09-18 Quandrant Holdings Cambridge Limited Solid dose delivery vehicle and methods of making same
US6455511B1 (en) 1994-09-22 2002-09-24 Quadrant Holdings Cambridge Limited Compositions for use in rehydration and nutrition during athletic exercise and methods of making same
US6468782B1 (en) 1996-12-05 2002-10-22 Quadrant Healthcare (Uk) Limited Methods of preserving prokaryotic cells and compositions obtained thereby
US6586006B2 (en) 1994-08-04 2003-07-01 Elan Drug Delivery Limited Solid delivery systems for controlled release of molecules incorporated therein and methods of making same
US6632648B1 (en) 1996-05-14 2003-10-14 Elan Drug Delivery Limited Methods of terminal sterilization of fibrinogen
US6964771B1 (en) 1995-06-07 2005-11-15 Elan Drug Delivery Limited Method for stably incorporating substances within dry, foamed glass matrices
US8168223B1 (en) 1997-09-29 2012-05-01 Novartis Pharma Ag Engineered particles and methods of use
US8246934B2 (en) 1997-09-29 2012-08-21 Novartis Ag Respiratory dispersion for metered dose inhalers comprising perforated microstructures
US8404217B2 (en) 2000-05-10 2013-03-26 Novartis Ag Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
US8709484B2 (en) 2000-05-10 2014-04-29 Novartis Ag Phospholipid-based powders for drug delivery
US8715623B2 (en) 2001-12-19 2014-05-06 Novartis Ag Pulmonary delivery of aminoglycoside
US8877162B2 (en) 2000-05-10 2014-11-04 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4076486A (en) * 1975-03-10 1978-02-28 University Of Southern California Method of burning a fossil fuel
DE2556561C2 (en) * 1975-12-16 1983-04-14 Boehringer Mannheim Gmbh, 6800 Mannheim Process for the production of porous tablets
IE45770B1 (en) * 1976-10-06 1982-11-17 Wyeth John & Brother Ltd Pharmaceutical dosage forms
GB1548022A (en) * 1976-10-06 1979-07-04 Wyeth John & Brother Ltd Pharmaceutial dosage forms
US4568547A (en) * 1979-08-30 1986-02-04 Herschler R J Solid pharmaceutical compositions comprising MSM and their production
US4883182A (en) * 1985-05-31 1989-11-28 Hughes Raymond J Tamper evident capsule and insert device
GB8624628D0 (en) * 1986-10-14 1986-11-19 Scras Soluble/splitable tablets
JP2614409B2 (en) * 1991-12-20 1997-05-28 ファイザー・インコーポレーテッド Porous shaped release formulation and method of making same
EP0620728B1 (en) * 1992-01-13 1997-01-08 Pfizer Inc. Preparation of tablets of increased strength
HUT75616A (en) * 1992-03-17 1997-05-28 Pfizer Method for prooucing porous delivery devices
KR100481583B1 (en) * 1996-06-14 2005-07-12 교와 핫꼬 고교 가부시끼가이샤 Tablets disintegrate quickly in the oral cavity
US8071128B2 (en) 1996-06-14 2011-12-06 Kyowa Hakko Kirin Co., Ltd. Intrabuccally rapidly disintegrating tablet and a production method of the tablets
AU733032C (en) * 1996-06-14 2002-01-03 Kyowa Hakko Kirin Co., Ltd. Intraorally rapidly disintegrable tablet
JP3152664B2 (en) 1996-08-13 2001-04-03 協和醗酵工業株式会社 Isotopic urea tablets
US20040023948A1 (en) * 1997-03-24 2004-02-05 Green Richard David Fast-dispersing dosage form containing 5-HT1 agonists
GT199900061A (en) * 1998-05-15 2000-10-14 Pfizer PHARMACEUTICAL FORMULATIONS.
CN1329487A (en) 1998-11-10 2002-01-02 特瓦制药工业有限公司 Dispersible compositions containing L-dopaethyl ester
GB9908014D0 (en) 1999-04-08 1999-06-02 Scherer Corp R P Pharmaceutical compositions
US6284270B1 (en) * 1999-08-04 2001-09-04 Drugtech Corporation Means for creating a mass having structural integrity
US20030185886A1 (en) * 2000-05-26 2003-10-02 Hanmi Pharm. Co., Ltd. Process for the preparation of rapidly disintegrating tablet
KR20010107754A (en) * 2000-05-26 2001-12-07 민경윤 Process for preparing rapidly disintegrating tablet for oral administration
GB0028709D0 (en) * 2000-11-24 2001-01-10 S P A Process
US6544552B2 (en) * 2001-01-11 2003-04-08 Particle And Coating Technologies, Inc. Method of producing porous tablets with improved dissolution properties
MXPA03007081A (en) * 2001-02-08 2004-10-15 Pharmacia Corp Rapid-onset medicament for the treatment of sexual dysfunction.
CA2440361A1 (en) * 2001-03-06 2002-09-12 Kyowa Hakko Kogyo Co. Ltd. Intraorally rapidly disintegrable preparation
US6509040B1 (en) 2001-06-22 2003-01-21 R.P. Scherer Corporation Fast dispersing dosage forms essentially free of mammalian gelatin
US9358214B2 (en) 2001-10-04 2016-06-07 Adare Pharmaceuticals, Inc. Timed, sustained release systems for propranolol
CA2480377A1 (en) * 2002-03-26 2003-10-09 Teva Pharmaceutical Industries Ltd. Drug microparticles
WO2004032853A2 (en) * 2002-10-04 2004-04-22 Pharmacia Corporation Compositions and methods for treating sexual dysfunction
AU2003284942A1 (en) * 2002-10-30 2004-06-07 Pharmacia Corporation Oral extended release tablets and methods of making and using the same
US8367111B2 (en) * 2002-12-31 2013-02-05 Aptalis Pharmatech, Inc. Extended release dosage forms of propranolol hydrochloride
US7749533B2 (en) * 2003-05-07 2010-07-06 Akina, Inc. Highly plastic granules for making fast melting tablets
US7390503B1 (en) 2003-08-22 2008-06-24 Barr Laboratories, Inc. Ondansetron orally disintegrating tablets
US8747895B2 (en) * 2004-09-13 2014-06-10 Aptalis Pharmatech, Inc. Orally disintegrating tablets of atomoxetine
US9884014B2 (en) * 2004-10-12 2018-02-06 Adare Pharmaceuticals, Inc. Taste-masked pharmaceutical compositions
NZ589750A (en) 2004-10-21 2012-07-27 Aptalis Pharmatech Inc Taste-masked pharmaceutical compositions with gastrosoluble pore-formers
KR101379297B1 (en) * 2004-10-28 2014-04-10 팬택 아게 A highly porous, fast-disintegrating solid dosage form and its way of manufacturing comprising the preparation of a powder and a freezedrying step
US20060105038A1 (en) * 2004-11-12 2006-05-18 Eurand Pharmaceuticals Limited Taste-masked pharmaceutical compositions prepared by coacervation
US9161918B2 (en) 2005-05-02 2015-10-20 Adare Pharmaceuticals, Inc. Timed, pulsatile release systems
GB0516604D0 (en) * 2005-08-12 2005-09-21 Sandoz Ag Rapidly dispersing/disintegrating compositions
US20090068262A1 (en) * 2007-04-04 2009-03-12 Ilan Zalit Rapid dissolution of combination products
CN101686942B (en) * 2007-06-27 2012-09-26 韩美药品株式会社 Method for preparing rapidly disintegrating formulation for oral administration and apparatus for preparing and packing the same
US20090060983A1 (en) * 2007-08-30 2009-03-05 Bunick Frank J Method And Composition For Making An Orally Disintegrating Dosage Form
AU2008318851B2 (en) * 2007-10-31 2014-04-17 Mcneil-Ppc, Inc. Orally disintegrated dosage form
US20120100212A1 (en) * 2009-07-06 2012-04-26 Kyorin Pharmaceutical, Co., Ltd. Tablet having hollow structure
US8784781B2 (en) 2009-09-24 2014-07-22 Mcneil-Ppc, Inc. Manufacture of chewing gum product with radiofrequency
US20110318411A1 (en) 2010-06-24 2011-12-29 Luber Joseph R Multi-layered orally disintegrating tablet and the manufacture thereof
US8313768B2 (en) 2009-09-24 2012-11-20 Mcneil-Ppc, Inc. Manufacture of tablet having immediate release region and sustained release region
US20110070286A1 (en) * 2009-09-24 2011-03-24 Andreas Hugerth Process for the manufacture of nicotine-comprising chewing gum and nicotine-comprising chewing gum manufactured according to said process
ES2668203T3 (en) 2009-12-02 2018-05-17 Adare Pharmaceuticals S.R.L. Fexofenadine microcapsules and compositions containing them
WO2011085181A1 (en) * 2010-01-08 2011-07-14 Eurand, Inc. Taste masked topiramate composition and an orally disintegrating tablet comprising the same
US9233491B2 (en) 2012-05-01 2016-01-12 Johnson & Johnson Consumer Inc. Machine for production of solid dosage forms
US9445971B2 (en) 2012-05-01 2016-09-20 Johnson & Johnson Consumer Inc. Method of manufacturing solid dosage form
US9511028B2 (en) 2012-05-01 2016-12-06 Johnson & Johnson Consumer Inc. Orally disintegrating tablet
MX368159B (en) 2014-01-10 2019-09-20 Johnson & Johnson Consumer Inc Process for making tablet using radiofrequency and lossy coated particles.
CN107595789B (en) 2016-04-21 2021-01-15 阿斯利康(瑞典)有限公司 Orally disintegrating tablet
US10493026B2 (en) 2017-03-20 2019-12-03 Johnson & Johnson Consumer Inc. Process for making tablet using radiofrequency and lossy coated particles

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1742515A (en) * 1924-10-08 1930-01-07 Ambrose J Mandell Method of making porous objects
US2887437A (en) * 1956-08-22 1959-05-19 Pfizer & Co C Palatable vitamin tablet containing an amino acid
US3175521A (en) * 1961-02-23 1965-03-30 Schering Corp Apparatus for punching miniature tablets
US3371984A (en) * 1963-09-06 1968-03-05 Colgate Palmolive Co Air freshener
DE1228029C2 (en) * 1964-05-09 1973-05-17 Merck Ag E Process for the production of tablets by pressing powder mixtures without prior granulation
US3450494A (en) * 1967-07-18 1969-06-17 Conrad J Gaiser Amorphous sodium silicate having inherent binding properties and method of producing same
US3639286A (en) * 1968-05-28 1972-02-01 Mario Ballestra Synthetic detergent in bar or cake form and the method to manufacture same
GB1303102A (en) * 1969-01-16 1973-01-17
US3719599A (en) * 1969-11-25 1973-03-06 Lepetit Spa Solid lubricant composition and method of preparation
LU60170A1 (en) * 1970-01-09 1971-11-18
US3653914A (en) * 1970-03-20 1972-04-04 Alberto Culver Co Production of tablets
US3632778A (en) * 1970-06-10 1972-01-04 Hoffmann La Roche Tablets containing l-dopa
US3739048A (en) * 1971-05-26 1973-06-12 Sumitomo Electric Industries Method of granulating powder
US3789119A (en) * 1971-06-01 1974-01-29 Parke Davis & Co Stabilized molded sublingual nitroglycerin tablets

Cited By (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6586006B2 (en) 1994-08-04 2003-07-01 Elan Drug Delivery Limited Solid delivery systems for controlled release of molecules incorporated therein and methods of making same
US6455511B1 (en) 1994-09-22 2002-09-24 Quadrant Holdings Cambridge Limited Compositions for use in rehydration and nutrition during athletic exercise and methods of making same
US6596702B2 (en) 1994-09-22 2003-07-22 Elan Drug Delivery Limited Compositions for use in rehydration and nutrition during athletic exercise and methods of making same
US7056495B2 (en) 1994-12-02 2006-06-06 Quadrant Drug Delivery Ltd. Solid dose delivery vehicle and methods of making same
US7785631B2 (en) 1994-12-02 2010-08-31 Quadrant Drug Delivery Limited Solid dose delivery vehicle and methods of making same
US6290991B1 (en) 1994-12-02 2001-09-18 Quandrant Holdings Cambridge Limited Solid dose delivery vehicle and methods of making same
US6331310B1 (en) 1994-12-02 2001-12-18 Quadrant Holdings Cambridge Limited Solid dose delivery vehicle and methods of making same
US7780991B2 (en) 1994-12-02 2010-08-24 Quadrant Drug Delivery Limited Solid dose delivery vehicle and methods of making same
US6565871B2 (en) 1994-12-02 2003-05-20 Elan Drug Delivery Ltd. Solid dose delivery vehicle and methods of making same
US7744925B2 (en) 1994-12-02 2010-06-29 Quadrant Drug Delivery Limited Solid dose delivery vehicle and methods of making same
US6811792B2 (en) 1994-12-02 2004-11-02 Quadrant Drug Delivery Ltd. Solid dose delivery vehicle and methods of making same
US6893657B2 (en) 1994-12-02 2005-05-17 Quadrant Drug Delivery Ltd. Solid dose delivery vehicle and methods of making same
US6964771B1 (en) 1995-06-07 2005-11-15 Elan Drug Delivery Limited Method for stably incorporating substances within dry, foamed glass matrices
US5762961A (en) * 1996-02-09 1998-06-09 Quadrant Holdings Cambridge Ltd. Rapidly soluble oral solid dosage forms, methods of making same, and compositions thereof
US5958455A (en) * 1996-02-09 1999-09-28 Quadrant Holdings Cambridge Ltd Oral solid dosage forms, methods of making same and compositions thereof
US6632648B1 (en) 1996-05-14 2003-10-14 Elan Drug Delivery Limited Methods of terminal sterilization of fibrinogen
US6468782B1 (en) 1996-12-05 2002-10-22 Quadrant Healthcare (Uk) Limited Methods of preserving prokaryotic cells and compositions obtained thereby
US8168223B1 (en) 1997-09-29 2012-05-01 Novartis Pharma Ag Engineered particles and methods of use
US8246934B2 (en) 1997-09-29 2012-08-21 Novartis Ag Respiratory dispersion for metered dose inhalers comprising perforated microstructures
US9554993B2 (en) 1997-09-29 2017-01-31 Novartis Ag Pulmonary delivery particles comprising an active agent
US8404217B2 (en) 2000-05-10 2013-03-26 Novartis Ag Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
US8709484B2 (en) 2000-05-10 2014-04-29 Novartis Ag Phospholipid-based powders for drug delivery
US8877162B2 (en) 2000-05-10 2014-11-04 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery
US8715623B2 (en) 2001-12-19 2014-05-06 Novartis Ag Pulmonary delivery of aminoglycoside
US9421166B2 (en) 2001-12-19 2016-08-23 Novartis Ag Pulmonary delivery of aminoglycoside

Also Published As

Publication number Publication date
FR2199973B1 (en) 1979-01-05
FR2199973A1 (en) 1974-04-19
JPS4969819A (en) 1974-07-05
IT998618B (en) 1976-02-20
SE395366B (en) 1977-08-15
DE2246013A1 (en) 1974-03-28
CH579394A5 (en) 1976-09-15
AT324568B (en) 1975-09-10
US3885026A (en) 1975-05-20

Similar Documents

Publication Publication Date Title
GB1381588A (en) Process for the preparation of porous tablets
CA1030687A (en) Powdery coating composition and process for preparing the same
CA981678A (en) (2-imidazolin-2-ylamino) substituted - quinoxalines and-quinazolines as antihypertensive agents
CA950218A (en) Process and system for increasing load-bearing capacity of soil
CA1007780A (en) Process for the preparation of polyurethane urea solutions
CA994327A (en) PROCESS FOR PREPARING 7-(.alpha.-HYDROXY-.alpha.-PHENYL) ACETAMIDO-3-(1-METHYL-1H-TETRAZOL-5-XYLTHIOMETHYL)-3-CEPHEM-4-CARBOXYLIC ACID AND DERIVATIVES THEREOF
IE38031B1 (en) Phenylalkanoic acids
IL42998A (en) Metabolically active derivatives of 3-(-4hydroxy-3,5-dialkylphenyl)propionic acid and some new such derivatives
CA936533A (en) 5-aryl-2,3-dihydro-2,2(or 3,3) dimethyl-5h-imidazo(2,1-a) isoindol-5-ols and 2(4,4(5,5) dimethyl-2-imidazolin-2-yl) bensophenone acid addition salts and processes for their preparation
CA981665A (en) 9-desoxy-prosta-5,9(10),13-trienoic acid derivatives and process for their preparation
GB1457546A (en) Pharmaceutical preparations comprising cephalosporin derivatives
CA1020157A (en) PROCESS FOR THE MANUFACTURE OF .beta.-(3-OXO-7.alpha.-THIOACYL-17.beta.-HYDROXY-4-ANDROSTEN-17.alpha.-YL)-PROPIONIC ACID.gamma.-LACTONES
CA996804A (en) Amplification of low-density polyyne images
CA931161A (en) PROCESS FOR PREPARING FREE-FLOWING .alpha.-OLEFIN SULFONATE POWDERS WHILE HYDROLYZING SULTONES
CA944892A (en) Process for the preparation of granular or powdery polyamide
GB1306820A (en) Derivatives of the kallikrein-trypsin inhibitor their preparation and use as pharmaceuticals
CA1020542A (en) PROCESS FOR THE MANUFACTURE OF .beta.-(3-OXO-7.alpha.-ACETYLTHIO-17.beta.-HYDROXY-4-ANDROSTEN-17.alpha.-YL)-PROPIONIC ACID .gamma.-LACTONE
GB1393226A (en) Therapeutic compositions and a process for the manufacture thereof
IL43562A (en) Pharmaceutical formulations containing allopurinol as inhibitor of xanthine oxidase
GB1456607A (en) Sublimable agricultural chemicals
CA974908A (en) Process for preparing nicotinamide adenine dinucleotide phosphate
CA901960A (en) PROCESS FOR STABILIZING .alpha.-LIPOIC ACID IN PHARMACEUTICAL SOLUTIONS
CA983643A (en) Polyurethane products, their use, and process for preparing such polyurethane products
GB1383292A (en) Process for preparing 1,3,4-thiadiazole-2-thiol compounds
CA897170A (en) Derivatives of 6,6-dimethyl-9-alkyl-9-azabicyclo (3.3.1) nonan-3-01 and process for preparing same

Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PE20 Patent expired after termination of 20 years

Effective date: 19930913