GB1375001A - - Google Patents
Info
- Publication number
- GB1375001A GB1375001A GB5177571A GB5177571A GB1375001A GB 1375001 A GB1375001 A GB 1375001A GB 5177571 A GB5177571 A GB 5177571A GB 5177571 A GB5177571 A GB 5177571A GB 1375001 A GB1375001 A GB 1375001A
- Authority
- GB
- United Kingdom
- Prior art keywords
- polynucleotides
- enzyme
- nov
- poly
- diphosphates
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 108091033319 polynucleotide Proteins 0.000 abstract 3
- 239000002157 polynucleotide Substances 0.000 abstract 3
- 102000040430 polynucleotide Human genes 0.000 abstract 3
- 102000004190 Enzymes Human genes 0.000 abstract 2
- 108090000790 Enzymes Proteins 0.000 abstract 2
- OIRDTQYFTABQOQ-KQYNXXCUSA-N adenosine Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O OIRDTQYFTABQOQ-KQYNXXCUSA-N 0.000 abstract 2
- 239000001177 diphosphate Substances 0.000 abstract 2
- 235000011180 diphosphates Nutrition 0.000 abstract 2
- -1 nucleoside diphosphates Chemical class 0.000 abstract 2
- UHDGCWIWMRVCDJ-UHFFFAOYSA-N 1-beta-D-Xylofuranosyl-NH-Cytosine Natural products O=C1N=C(N)C=CN1C1C(O)C(O)C(CO)O1 UHDGCWIWMRVCDJ-UHFFFAOYSA-N 0.000 abstract 1
- 241000589149 Azotobacter vinelandii Species 0.000 abstract 1
- 239000002126 C01EB10 - Adenosine Substances 0.000 abstract 1
- UHDGCWIWMRVCDJ-PSQAKQOGSA-N Cytidine Natural products O=C1N=C(N)C=CN1[C@@H]1[C@@H](O)[C@@H](O)[C@H](CO)O1 UHDGCWIWMRVCDJ-PSQAKQOGSA-N 0.000 abstract 1
- 229930010555 Inosine Natural products 0.000 abstract 1
- UGQMRVRMYYASKQ-KQYNXXCUSA-N Inosine Chemical compound O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N1C2=NC=NC(O)=C2N=C1 UGQMRVRMYYASKQ-KQYNXXCUSA-N 0.000 abstract 1
- 102000009097 Phosphorylases Human genes 0.000 abstract 1
- 108010073135 Phosphorylases Proteins 0.000 abstract 1
- 108091036414 Polyinosinic:polycytidylic acid Proteins 0.000 abstract 1
- DRTQHJPVMGBUCF-XVFCMESISA-N Uridine Natural products O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N1C(=O)NC(=O)C=C1 DRTQHJPVMGBUCF-XVFCMESISA-N 0.000 abstract 1
- 229960005305 adenosine Drugs 0.000 abstract 1
- DRTQHJPVMGBUCF-PSQAKQOGSA-N beta-L-uridine Natural products O[C@H]1[C@@H](O)[C@H](CO)O[C@@H]1N1C(=O)NC(=O)C=C1 DRTQHJPVMGBUCF-PSQAKQOGSA-N 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- UHDGCWIWMRVCDJ-ZAKLUEHWSA-N cytidine Chemical compound O=C1N=C(N)C=CN1[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O1 UHDGCWIWMRVCDJ-ZAKLUEHWSA-N 0.000 abstract 1
- 230000002255 enzymatic effect Effects 0.000 abstract 1
- 229960003786 inosine Drugs 0.000 abstract 1
- 159000000003 magnesium salts Chemical class 0.000 abstract 1
- 239000002777 nucleoside Substances 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- DRTQHJPVMGBUCF-UHFFFAOYSA-N uracil arabinoside Natural products OC1C(O)C(CO)OC1N1C(=O)NC(=O)C=C1 DRTQHJPVMGBUCF-UHFFFAOYSA-N 0.000 abstract 1
- 229940045145 uridine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7040268A FR2112784A5 (enExample) | 1970-11-09 | 1970-11-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1375001A true GB1375001A (enExample) | 1974-11-27 |
Family
ID=9063972
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5177571A Expired GB1375001A (enExample) | 1970-11-09 | 1971-11-08 |
Country Status (6)
| Country | Link |
|---|---|
| BE (1) | BE775021A (enExample) |
| CA (1) | CA979831A (enExample) |
| DE (1) | DE2059937A1 (enExample) |
| FR (1) | FR2112784A5 (enExample) |
| GB (1) | GB1375001A (enExample) |
| NL (1) | NL7115407A (enExample) |
-
1970
- 1970-11-09 FR FR7040268A patent/FR2112784A5/fr not_active Expired
- 1970-12-05 DE DE19702059937 patent/DE2059937A1/de active Pending
-
1971
- 1971-11-05 BE BE775021A patent/BE775021A/xx unknown
- 1971-11-08 CA CA127,088A patent/CA979831A/en not_active Expired
- 1971-11-08 GB GB5177571A patent/GB1375001A/en not_active Expired
- 1971-11-09 NL NL7115407A patent/NL7115407A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE2059937A1 (de) | 1972-05-18 |
| FR2112784A5 (enExample) | 1972-06-23 |
| BE775021A (fr) | 1972-05-05 |
| CA979831A (en) | 1975-12-16 |
| NL7115407A (enExample) | 1972-05-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Okuda et al. | Mechanism of the phosphorylation of thymidine by the culture filtrate of Clostridium perfringens and rat liver extract | |
| Momparler | Effect of cytosine arabinoside 5′-triphosphate on mammalian DNA polymerase | |
| Abrams et al. | Transformation of Inosinic Acid to Adenylic and Guanylic Acids in a Soluble Enzyme SYSTEM1 | |
| Furth et al. | Inhibition of mammalian DNA polymerase by the 5′-triphosphate of 9-β-D-arabinofuranosyladenine | |
| Brockman | Biochemical aspects of mercaptopurine inhibition and resistance | |
| US5770407A (en) | Process for preparing nucleotide inhibitors of glycosyltransferases | |
| SCHULMAN | Purines and pyrimidines | |
| Hansen et al. | [38] UDP-glucose pyrophosphorylase (crystalline) from liver | |
| GB1139365A (en) | Process of preparing 5'-nucleotides | |
| ES382365A1 (es) | Un metodo de preparacion de citidina-difosfato-colina. | |
| Munch-Petersen | Enzymatic synthesis and pyrophosphorolysis of guanosine diphosphate mannose | |
| GB1375001A (enExample) | ||
| Villarejo et al. | Rhodanese-catalyzed reduction of thiosulfate by reduced lipoic acid | |
| Pazur et al. | a Role for Thymidine Nucleotides in the Biosynthesis of L-RHAMNOSE1 | |
| Henderson et al. | Naturally occurring acid-soluble nucleotides | |
| Frederiksen et al. | The effect of deoxyadenosine 1-N-oxide on nucleic acid synthesis in ascites tumor cells in vitro | |
| Takaku et al. | 8-QUINOLYL NUCLEOSIDE 5′-PHOSPHATES AS A USEFUL INTERMEDIATE FOR THE SYNTHESIS OF NUCLEOSIDE 5′-DI-AND 5′-TRI-PHOSPHATES | |
| Freimund et al. | Enzymatic synthesis of D-glucosone 6-phosphate (D-arabino-hexos-2-ulose 6-(dihydrogen phosphate)) and NMR analysis of its isomeric forms | |
| Kiran et al. | Design and synthesis of a nucleoside and a phosphonate analogue constructed on a branched-threo-tetrofuranose skeleton | |
| FR1601055A (en) | Preparation of 5-ribonucleotides seasoning agents | |
| Mendicino et al. | Regulation of the Synthesis of Nucleoside Diphosphate Sugars in Reticulo‐Endothelial Tissues | |
| Ichihara et al. | Enzymatic formation of uridine diphosphate N‐acetyl‐D‐mannosaminuronic acid | |
| Moore et al. | Biosynthesis of RNA cytosine and RNA purines: differential inhibition by diazo-oxo-norleucine | |
| GB1507175A (en) | Process for producing purine nucleoside 5'-phosphate(mono,di or tri)3'(2')-diphosphates | |
| Saneyoshi et al. | Synthetic Nucleosides and Nucleotides. XXXV.> Synthesis and Biological Evaluations of 5-Fluoropyrimidine Nucleosides and Nucleotides of 3-Deoxy-β-D-ribofuranose and Related Compounds |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |