GB1358727A - Purification of glyburide - Google Patents
Purification of glyburideInfo
- Publication number
- GB1358727A GB1358727A GB4205871A GB4205871A GB1358727A GB 1358727 A GB1358727 A GB 1358727A GB 4205871 A GB4205871 A GB 4205871A GB 4205871 A GB4205871 A GB 4205871A GB 1358727 A GB1358727 A GB 1358727A
- Authority
- GB
- United Kingdom
- Prior art keywords
- glyburide
- purification
- sept
- cyclohexylurea
- methoxybenzamido
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229960004580 glibenclamide Drugs 0.000 title abstract 2
- ZNNLBTZKUZBEKO-UHFFFAOYSA-N glyburide Chemical compound COC1=CC=C(Cl)C=C1C(=O)NCCC1=CC=C(S(=O)(=O)NC(=O)NC2CCCCC2)C=C1 ZNNLBTZKUZBEKO-UHFFFAOYSA-N 0.000 title abstract 2
- 238000000746 purification Methods 0.000 title abstract 2
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- -1 alkali metal salt Chemical class 0.000 abstract 1
- XPYGGHVSFMUHLH-UUSULHAXSA-N falecalcitriol Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@@H](CCCC(O)(C(F)(F)F)C(F)(F)F)C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C XPYGGHVSFMUHLH-UUSULHAXSA-N 0.000 abstract 1
- 230000001172 regenerating effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- YROXIXLRRCOBKF-UHFFFAOYSA-N sulfonylurea Chemical compound OC(=N)N=S(=O)=O YROXIXLRRCOBKF-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
- C07C311/52—Y being a hetero atom
- C07C311/54—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea
- C07C311/57—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings
- C07C311/59—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings having nitrogen atoms of the sulfonylurea groups bound to carbon atoms of rings other than six-membered aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA92744 | 1970-09-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1358727A true GB1358727A (en) | 1974-07-03 |
Family
ID=4087558
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4205871A Expired GB1358727A (en) | 1970-09-10 | 1971-09-09 | Purification of glyburide |
Country Status (3)
| Country | Link |
|---|---|
| CA (1) | CA889876A (enExample) |
| DE (1) | DE2144303A1 (enExample) |
| GB (1) | GB1358727A (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6830760B2 (en) | 2000-01-14 | 2004-12-14 | Bristol-Myers Squibb Company | Glyburide composition |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3833439A1 (de) * | 1988-10-01 | 1991-09-12 | Hoechst Ag | Verfahren zur mikronisierung von glibenclamid |
-
1970
- 1970-09-10 CA CA889876D patent/CA889876A/en not_active Expired
-
1971
- 1971-09-03 DE DE19712144303 patent/DE2144303A1/de not_active Withdrawn
- 1971-09-09 GB GB4205871A patent/GB1358727A/en not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6830760B2 (en) | 2000-01-14 | 2004-12-14 | Bristol-Myers Squibb Company | Glyburide composition |
Also Published As
| Publication number | Publication date |
|---|---|
| CA889876A (en) | 1972-01-04 |
| DE2144303A1 (de) | 1972-03-23 |
| DE2144303B2 (enExample) | 1974-09-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |