GB1340769A - Process for the manufacture of a 9alpha-chloro-11beta-hydroxy- steroids - Google Patents

Process for the manufacture of a 9alpha-chloro-11beta-hydroxy- steroids

Info

Publication number
GB1340769A
GB1340769A GB2338671*A GB2338671A GB1340769A GB 1340769 A GB1340769 A GB 1340769A GB 2338671 A GB2338671 A GB 2338671A GB 1340769 A GB1340769 A GB 1340769A
Authority
GB
United Kingdom
Prior art keywords
steroids
hydroxy
chloro
9alpha
11beta
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2338671*A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Publication of GB1340769A publication Critical patent/GB1340769A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)

Abstract

1340769 Preparation of 9α-chloro-11#- hydroxy-steroids SCHERING AG 19 April 1971 [7 March 1970] 23386/71 Heading C2U 9a-Chloro-11#-hydroxy-steroids are prepared by treating #<SP>9(11)</SP>-steroids in an inert anhydrous solvent of dielectric constant above 25 at 25‹ C. with t-butyl hypochlorite and perchloric acid. Suitable solvents are nitromethane, nitroethane and nitrobenzene. In the products acyloxy groups may be hydrolysed and hydroxy groups acylated.
GB2338671*A 1970-03-07 1971-04-19 Process for the manufacture of a 9alpha-chloro-11beta-hydroxy- steroids Expired GB1340769A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19702011559 DE2011559B2 (en) 1970-03-07 1970-03-07 PROCESS FOR THE PREPARATION OF 9ALPHA-CHLORINE-11BETA-HYDROXYSTEROIDS

Publications (1)

Publication Number Publication Date
GB1340769A true GB1340769A (en) 1974-01-30

Family

ID=5764798

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2338671*A Expired GB1340769A (en) 1970-03-07 1971-04-19 Process for the manufacture of a 9alpha-chloro-11beta-hydroxy- steroids

Country Status (10)

Country Link
US (1) US3729495A (en)
JP (1) JPS547791B1 (en)
CH (1) CH568337A5 (en)
DE (1) DE2011559B2 (en)
DK (1) DK129040B (en)
FR (1) FR2084260A5 (en)
GB (1) GB1340769A (en)
NL (1) NL7103080A (en)
SU (1) SU434650A3 (en)
YU (1) YU34139B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3071122D1 (en) * 1979-11-16 1985-10-31 Sterosynt Ltd 6-alpha-fluoro-9-alpha-chloro-prednisolone-17,21 diesters, pharmaceutical compositions containing them and intermediates
WO2009045539A2 (en) 2007-10-05 2009-04-09 Nektar Therapeutics Al, Corporation Oligomer-corticosteroid conjugates

Also Published As

Publication number Publication date
NL7103080A (en) 1971-09-09
DE2011559A1 (en) 1971-09-23
DK129040B (en) 1974-08-12
YU34139B (en) 1978-12-31
JPS547791B1 (en) 1979-04-10
YU52071A (en) 1978-06-30
CH568337A5 (en) 1975-10-31
FR2084260A5 (en) 1971-12-17
DK129040C (en) 1975-02-24
US3729495A (en) 1973-04-24
SU434650A3 (en) 1974-06-30
DE2011559B2 (en) 1973-03-08
DE2011559C3 (en) 1973-10-18

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee