GB1334980A - Preparation of retinyl halides - Google Patents

Preparation of retinyl halides

Info

Publication number
GB1334980A
GB1334980A GB2336872A GB2336872A GB1334980A GB 1334980 A GB1334980 A GB 1334980A GB 2336872 A GB2336872 A GB 2336872A GB 2336872 A GB2336872 A GB 2336872A GB 1334980 A GB1334980 A GB 1334980A
Authority
GB
United Kingdom
Prior art keywords
retinyl
halides
retinol
preparation
reacting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2336872A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc SA
Original Assignee
Rhone Poulenc SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc SA filed Critical Rhone Poulenc SA
Publication of GB1334980A publication Critical patent/GB1334980A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/04—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

1334980 Retinyl halides RHONE-POULENC SA 18 May 1972 [19 May 1971] 23368/72 Heading C2V Retinyl halides are obtained by reacting 1- retinol (vitamin A alcohol) or the isomer 3- retinol, with a halogenating reagent in an inert solvent and at below 0‹ C. In examples retinyl bromide and retinyl chloride are obtained by reacting 3-retinol with phosphorus tribromide and with phosphorus trichloride respectively.
GB2336872A 1971-05-19 1972-05-18 Preparation of retinyl halides Expired GB1334980A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR717118167A FR2138211B1 (en) 1971-05-19 1971-05-19

Publications (1)

Publication Number Publication Date
GB1334980A true GB1334980A (en) 1973-10-24

Family

ID=9077310

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2336872A Expired GB1334980A (en) 1971-05-19 1972-05-18 Preparation of retinyl halides

Country Status (10)

Country Link
JP (1) JPS5233628B1 (en)
BE (1) BE783671A (en)
CH (1) CH532567A (en)
DE (1) DE2224706B2 (en)
ES (1) ES402985A1 (en)
FR (1) FR2138211B1 (en)
GB (1) GB1334980A (en)
IL (1) IL39462A (en)
IT (1) IT1043881B (en)
NL (1) NL7206337A (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000061530A1 (en) * 1999-04-08 2000-10-19 Sumitomo Chemical Company, Limited Process for the preparation of halogenated compounds
US20140330005A1 (en) * 2011-11-28 2014-11-06 Case Western Reserve University Polysaccharide therapeutic conjugates
US10925980B2 (en) 2014-08-04 2021-02-23 Case Western Reserve University Molecular probes and methods of use
US11129845B2 (en) 2014-06-18 2021-09-28 Case Western Reserve University Compositions and methods for the delivery of nucleic acids
US11407786B2 (en) 2015-06-18 2022-08-09 Case Western Reserve University Compositions and methods for the delivery of nucleic acids
US11793853B2 (en) 2014-05-30 2023-10-24 Case Western Reserve University Retinylamine derivitives for treatment of ocular disorders

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2234284B1 (en) * 1973-06-25 1978-01-13 Hoffmann La Roche
DE2717737A1 (en) * 1977-04-21 1978-10-26 Basf Ag DERIVATIVES OF 8-DEHYDRO-VITAMIN-A AND THE PROCESS FOR THEIR PRODUCTION
DE2843915A1 (en) * 1978-10-07 1980-04-24 Basf Ag N-BENZOYL RETINYLAMINE

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000061530A1 (en) * 1999-04-08 2000-10-19 Sumitomo Chemical Company, Limited Process for the preparation of halogenated compounds
US20140330005A1 (en) * 2011-11-28 2014-11-06 Case Western Reserve University Polysaccharide therapeutic conjugates
US10226536B2 (en) * 2011-11-28 2019-03-12 Case Western Reserve University Polysaccharide therapeutic conjugates
US11065338B2 (en) 2011-11-28 2021-07-20 Case Western Reserve University Polysaccharide therapeutic conjugates
US11793853B2 (en) 2014-05-30 2023-10-24 Case Western Reserve University Retinylamine derivitives for treatment of ocular disorders
US11129845B2 (en) 2014-06-18 2021-09-28 Case Western Reserve University Compositions and methods for the delivery of nucleic acids
US10925980B2 (en) 2014-08-04 2021-02-23 Case Western Reserve University Molecular probes and methods of use
US11738099B2 (en) 2014-08-04 2023-08-29 Case Western Reserve University Molecular probes and methods of use
US11407786B2 (en) 2015-06-18 2022-08-09 Case Western Reserve University Compositions and methods for the delivery of nucleic acids

Also Published As

Publication number Publication date
JPS5233628B1 (en) 1977-08-30
IL39462A (en) 1974-11-29
IL39462A0 (en) 1972-07-26
FR2138211B1 (en) 1973-05-11
ES402985A1 (en) 1975-04-16
NL7206337A (en) 1972-11-21
FR2138211A1 (en) 1973-01-05
BE783671A (en) 1972-11-20
CH532567A (en) 1973-01-15
DE2224706A1 (en) 1972-12-14
IT1043881B (en) 1980-02-29
DE2224706B2 (en) 1974-10-31

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee