GB1330609A - 4-n-lower alkanoyl hydroxylamino 4- aminodiphenylsulphone compounds - Google Patents
4-n-lower alkanoyl hydroxylamino 4- aminodiphenylsulphone compoundsInfo
- Publication number
- GB1330609A GB1330609A GB1330609DA GB1330609A GB 1330609 A GB1330609 A GB 1330609A GB 1330609D A GB1330609D A GB 1330609DA GB 1330609 A GB1330609 A GB 1330609A
- Authority
- GB
- United Kingdom
- Prior art keywords
- hydroxylamino
- compounds
- sulphone
- sulphide
- aminodiphenylsulphone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000001589 carboacyl group Chemical group 0.000 abstract 1
- KZTYYGOKRVBIMI-UHFFFAOYSA-N diphenyl sulfone Chemical compound C=1C=CC=CC=1S(=O)(=O)C1=CC=CC=C1 KZTYYGOKRVBIMI-UHFFFAOYSA-N 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/07—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms
- C07C205/11—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms having nitro groups bound to carbon atoms of six-membered aromatic rings
- C07C205/12—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms having nitro groups bound to carbon atoms of six-membered aromatic rings the six-membered aromatic ring or a condensed ring system containing that ring being substituted by halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
1330609 4 - (Alkanoyl) - hydroxylamino - 4<SP>1</SP>- amino-diphenylsulphones SMITH KLINE & FRENCH LABORATORIES 9 May 1972 21603/72 Heading C2C [Also in Division A5] Novel, therapeutic compounds (I) where R 1 is NH 2 , NHCOR 4 or N(.OR 3 )(.COR 4 ), R 2 is H or alkyl, R 3 is H or COR 5 and R 4 and R 5 are alkyl or dialkylaminoalkylene, are made by acylating corresponding -NHOH compounds and if desired hydrolysing the products obtained. The following compounds are also prepared: 4 - amino - 4<SP>1</SP> - nitrodiphenylsulphide, 4 - acetamido - 4<SP>1</SP> - nitrodiphenyl - sulphide and -sulphone, 4 - acetamido - 4<SP>1</SP> - hydraxylaminodiphenylsulphane, 4 - nitro - 4<SP>1</SP> - trifluoroacetamidodiphenyl-sulphide and -sulphone, 4-hydroxylamino - 4<SP>1</SP> - trifluoroacetamidodiphenylsulphone, 4 - (N,O - diacetylhydroxylamino)- 4<SP>1</SP>- trifluoroacetamidodiphenylsulphone, 3-methyl- 4,4<SP>1</SP> - dinitro - diphenyl - sulphide and -sulphone, 4,4<SP>1</SP> - dihydroxylamino - 3 - methyldiphenylsulphone and 3 - ethyl - 4,4<SP>1</SP> - dinitrodiphenylsulphide.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB2160372 | 1972-05-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1330609A true GB1330609A (en) | 1973-09-19 |
Family
ID=10165699
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1330609D Expired GB1330609A (en) | 1972-05-09 | 1972-05-09 | 4-n-lower alkanoyl hydroxylamino 4- aminodiphenylsulphone compounds |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB1330609A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0165422A1 (en) * | 1984-05-22 | 1985-12-27 | Dr. Karl Thomae GmbH | Substituted bis-(4-aminophenyl)-sulphones, their preparation and their use as medicines |
US9018411B2 (en) | 2009-12-07 | 2015-04-28 | Cardioxyl Pharmaceuticals, Inc. | Bis-acylated hydroxylamine derivatives |
-
1972
- 1972-05-09 GB GB1330609D patent/GB1330609A/en not_active Expired
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0165422A1 (en) * | 1984-05-22 | 1985-12-27 | Dr. Karl Thomae GmbH | Substituted bis-(4-aminophenyl)-sulphones, their preparation and their use as medicines |
US9018411B2 (en) | 2009-12-07 | 2015-04-28 | Cardioxyl Pharmaceuticals, Inc. | Bis-acylated hydroxylamine derivatives |
US9458127B2 (en) | 2009-12-07 | 2016-10-04 | Cardioxyl Pharmaceuticals, Inc. | Bis-acylated hydroxylamine derivatives |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed | ||
PLNP | Patent lapsed through nonpayment of renewal fees |