GB1330563A - 9beta, 10alpha-steroids their preparation and compositions containing the same - Google Patents
9beta, 10alpha-steroids their preparation and compositions containing the sameInfo
- Publication number
- GB1330563A GB1330563A GB2284771A GB2284771A GB1330563A GB 1330563 A GB1330563 A GB 1330563A GB 2284771 A GB2284771 A GB 2284771A GB 2284771 A GB2284771 A GB 2284771A GB 1330563 A GB1330563 A GB 1330563A
- Authority
- GB
- United Kingdom
- Prior art keywords
- hydroxy
- methylene
- compounds
- oxo
- dione
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000203 mixture Substances 0.000 title 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 7
- 150000001875 compounds Chemical class 0.000 abstract 5
- RJKFOVLPORLFTN-LEKSSAKUSA-N Progesterone Natural products C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(=O)C)[C@@]1(C)CC2 RJKFOVLPORLFTN-LEKSSAKUSA-N 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- RJKFOVLPORLFTN-UHFFFAOYSA-N progesterone acetate Natural products C1CC2=CC(=O)CCC2(C)C2C1C1CCC(C(=O)C)C1(C)CC2 RJKFOVLPORLFTN-UHFFFAOYSA-N 0.000 abstract 4
- 238000006243 chemical reaction Methods 0.000 abstract 3
- 238000005886 esterification reaction Methods 0.000 abstract 3
- KDLHZDBZIXYQEI-UHFFFAOYSA-N Palladium Chemical compound [Pd] KDLHZDBZIXYQEI-UHFFFAOYSA-N 0.000 abstract 2
- 230000032050 esterification Effects 0.000 abstract 2
- YNZKCQFVSNOJKX-UHFFFAOYSA-N 2-ethyl-2-(ethylamino)butanoic acid Chemical compound CCNC(CC)(CC)C(O)=O YNZKCQFVSNOJKX-UHFFFAOYSA-N 0.000 abstract 1
- 229910004261 CaF 2 Inorganic materials 0.000 abstract 1
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- -1 alkali metal acetate Chemical class 0.000 abstract 1
- 238000009903 catalytic hydrogenation reaction Methods 0.000 abstract 1
- 238000006555 catalytic reaction Methods 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- AHXGRMIPHCAXFP-UHFFFAOYSA-L chromyl dichloride Chemical compound Cl[Cr](Cl)(=O)=O AHXGRMIPHCAXFP-UHFFFAOYSA-L 0.000 abstract 1
- 230000018044 dehydration Effects 0.000 abstract 1
- 238000006297 dehydration reaction Methods 0.000 abstract 1
- 238000006356 dehydrogenation reaction Methods 0.000 abstract 1
- 238000006251 dihalogenation reaction Methods 0.000 abstract 1
- 150000002085 enols Chemical class 0.000 abstract 1
- 238000006266 etherification reaction Methods 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
- 230000002140 halogenating effect Effects 0.000 abstract 1
- 238000005984 hydrogenation reaction Methods 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 238000006317 isomerization reaction Methods 0.000 abstract 1
- LGRLWUINFJPLSH-UHFFFAOYSA-N methanide Chemical compound [CH3-] LGRLWUINFJPLSH-UHFFFAOYSA-N 0.000 abstract 1
- 238000005822 methylenation reaction Methods 0.000 abstract 1
- 229910052763 palladium Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
- C07J53/002—Carbocyclic rings fused
- C07J53/004—3 membered carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL7003064A NL7003064A (es) | 1970-03-04 | 1970-03-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1330563A true GB1330563A (en) | 1973-09-19 |
Family
ID=19809490
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2284771A Expired GB1330563A (en) | 1970-03-04 | 1971-04-19 | 9beta, 10alpha-steroids their preparation and compositions containing the same |
Country Status (13)
| Country | Link |
|---|---|
| JP (4) | JPS5038103B1 (es) |
| AT (4) | AT312828B (es) |
| BE (1) | BE763754A (es) |
| CA (1) | CA972350A (es) |
| CH (1) | CH564944A5 (es) |
| DE (1) | DE2110084A1 (es) |
| ES (4) | ES388854A1 (es) |
| FR (1) | FR2085668B1 (es) |
| GB (1) | GB1330563A (es) |
| IL (1) | IL36324A0 (es) |
| NL (1) | NL7003064A (es) |
| SE (1) | SE373750B (es) |
| ZA (1) | ZA711332B (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITBZ20030005A1 (it) | 2003-01-30 | 2004-07-31 | High Technology Invest Bv | Dispositivo pressore per la conduzione di fune in sistemi di trasporto a trazione di fune. |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3198792A (en) * | 1962-06-12 | 1965-08-03 | Philips Corp | 10alpha methyl, 9beta hormonal steroids |
| GB1247661A (en) * | 1967-07-11 | 1971-09-29 | Philips Nv | NEW 9beta,10alpha-STEROIDS AND METHODS OF PRODUCING THE SAME |
-
1970
- 1970-03-04 NL NL7003064A patent/NL7003064A/xx unknown
-
1971
- 1971-03-01 SE SE7102589A patent/SE373750B/xx unknown
- 1971-03-01 CH CH295471A patent/CH564944A5/xx not_active IP Right Cessation
- 1971-03-02 AT AT414172A patent/AT312828B/de not_active IP Right Cessation
- 1971-03-02 AT AT414072A patent/AT316769B/de not_active IP Right Cessation
- 1971-03-02 AT AT176671A patent/AT315390B/de not_active IP Right Cessation
- 1971-03-02 CA CA106,613A patent/CA972350A/en not_active Expired
- 1971-03-02 AT AT413972A patent/AT316768B/de not_active IP Right Cessation
- 1971-03-02 ZA ZA711332A patent/ZA711332B/xx unknown
- 1971-03-02 IL IL36324A patent/IL36324A0/xx unknown
- 1971-03-03 DE DE19712110084 patent/DE2110084A1/de active Pending
- 1971-03-03 ES ES388854A patent/ES388854A1/es not_active Expired
- 1971-03-03 BE BE763754A patent/BE763754A/xx unknown
- 1971-03-04 FR FR7107523A patent/FR2085668B1/fr not_active Expired
- 1971-03-04 JP JP46011246A patent/JPS5038103B1/ja active Pending
- 1971-04-19 GB GB2284771A patent/GB1330563A/en not_active Expired
- 1971-11-22 ES ES397228A patent/ES397228A1/es not_active Expired
- 1971-11-22 ES ES397231A patent/ES397231A1/es not_active Expired
- 1971-11-22 ES ES397229A patent/ES397229A1/es not_active Expired
-
1974
- 1974-12-13 JP JP49143367A patent/JPS50105662A/ja active Pending
- 1974-12-13 JP JP49143366A patent/JPS50105661A/ja active Pending
- 1974-12-13 JP JP49143365A patent/JPS50105660A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| FR2085668B1 (es) | 1974-08-02 |
| BE763754A (fr) | 1971-09-03 |
| IL36324A0 (en) | 1971-05-26 |
| AT312828B (de) | 1974-01-25 |
| ES397231A1 (es) | 1975-04-01 |
| NL7003064A (es) | 1971-09-07 |
| JPS50105660A (es) | 1975-08-20 |
| JPS50105661A (es) | 1975-08-20 |
| CA972350A (en) | 1975-08-05 |
| FR2085668A1 (es) | 1971-12-31 |
| AT316769B (de) | 1974-07-25 |
| DE2110084A1 (de) | 1971-09-16 |
| ZA711332B (en) | 1972-10-25 |
| ES397229A1 (es) | 1975-04-01 |
| CH564944A5 (es) | 1975-08-15 |
| ES388854A1 (es) | 1974-03-16 |
| JPS50105662A (es) | 1975-08-20 |
| ES397228A1 (es) | 1975-04-01 |
| AT315390B (de) | 1974-05-27 |
| AT316768B (de) | 1974-07-25 |
| JPS5038103B1 (es) | 1975-12-06 |
| SE373750B (es) | 1975-02-17 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB1494097A (en) | D-homo-20-keto-pregnanes | |
| GB1190403A (en) | 4-Hydroxy-2-Butenoic Acid Lactones | |
| GB1330563A (en) | 9beta, 10alpha-steroids their preparation and compositions containing the same | |
| Bowers et al. | Steroids. CXLIII. 1 Transannular Reactions at Saturated Carbon Atoms. Part 1. C-3, 9-Oxide Formation | |
| GB1365469A (en) | Steroids of the d-homopregnane series | |
| GB1495531A (en) | 11beta-alkyl steroids of the estrane series | |
| GB1146992A (en) | Improvements in or relating to novel steroids and the manufacture thereof | |
| GB1063816A (en) | 10-a-methyl steroids | |
| US3793350A (en) | Process for preparing 17alpha,21-dihydroxy-20-keto-pregnanes,derivatives and intermediates thereof | |
| US3190855A (en) | Water-soluble steroids and a method for preparing the same | |
| US3194832A (en) | 18-nor-d-homo-steroids | |
| GB1211836A (en) | Novel 15,16-alkylidene-steroids and a process for the manufacture thereof | |
| GB928302A (en) | í¸-pregnene compounds | |
| US3228933A (en) | 3-enol ethers of 6-methyl-3-oxo-deta4-steroids and process for preparing same | |
| US3155692A (en) | 3-enol ethers of 2-hydroxymethyl-3-oxo-5alpha-steroids and process for preparing same | |
| US3053858A (en) | 10-fluoro-19-nor steroids | |
| US3592828A (en) | 17 alpha-(1',3'-alkadiynyl)-17 beta-hydroxy (17 beta-alkoxy)-steroids | |
| US3467713A (en) | Process for the defluorination of fluorosteroids | |
| US3386994A (en) | Pregna-4, 6-diene-and 19-norpregna-4, 6-diene-3beta, 16, 17alpha-triol steroids, derivatives thereof, and processes for their preparation | |
| US3375167A (en) | 6-hydroxymethyl-3-oxo-4, 6-dienic steroids, acyl derivatives thereof, and process for preparing same | |
| GB1336763A (en) | 9beta, 10alpha-steroids their preparation and pharmaceutical preparations containing the same | |
| US3780072A (en) | 3-enolethers of delta 1-3-keto-5alpha-steroids and process for their preparation | |
| GB978540A (en) | Improvements in or relating to the production of 16ª-alkylthio-17-oxo-steroids | |
| US3048605A (en) | 16, 16-difluoroestratrienes | |
| US3126398A (en) | Fluorevated androstenes and process |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |