GB1316772A - Production of nucleotide anhydrides - Google Patents

Production of nucleotide anhydrides

Info

Publication number
GB1316772A
GB1316772A GB2817270A GB2817270A GB1316772A GB 1316772 A GB1316772 A GB 1316772A GB 2817270 A GB2817270 A GB 2817270A GB 2817270 A GB2817270 A GB 2817270A GB 1316772 A GB1316772 A GB 1316772A
Authority
GB
United Kingdom
Prior art keywords
monophosphate
nucleoside
anhydrides
nucleotide
pyridine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2817270A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yamasa Shoyu KK
Original Assignee
Yamasa Shoyu KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamasa Shoyu KK filed Critical Yamasa Shoyu KK
Publication of GB1316772A publication Critical patent/GB1316772A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C07H1/02—Phosphorylation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)

Abstract

1316772 Nucleotide anhydrides YAMASA SHOYU KK 10 June 1970 [12 June 1969] 28172/70 Heading C2P Nucleotide anhydrides are produced by reacting a nucleoside-5<SP>1</SP>-monophosphate with diphenyl phosphorochloridate or tetraphenyl pyrophosphate in a solvent and in the presence of an amine in an amount of more than 0À5 to 2 moles per one mole of the nucleoside-5<SP>1</SP>-monophosphate, and then adding to the product a solution of an acid, or a salt thereof with a tertiary alkylamine or a quaternary alkylammonium hydroxide, which is weaker in its acidity than diphenyl phosphate, in pyridine or one of its derivatives, or in other solvents, prior to being dissolved in pyridine or one of its derivatives. The nucleoside-5<SP>1</SP>-monophosphate may be used in the form of an alkylammonium salt.
GB2817270A 1969-06-12 1970-06-10 Production of nucleotide anhydrides Expired GB1316772A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP44045786A JPS4910674B1 (en) 1969-06-12 1969-06-12

Publications (1)

Publication Number Publication Date
GB1316772A true GB1316772A (en) 1973-05-16

Family

ID=12728948

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2817270A Expired GB1316772A (en) 1969-06-12 1970-06-10 Production of nucleotide anhydrides

Country Status (5)

Country Link
US (1) US3701772A (en)
JP (1) JPS4910674B1 (en)
CA (1) CA931141A (en)
FR (1) FR2051064A5 (en)
GB (1) GB1316772A (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3960840A (en) * 1972-12-29 1976-06-01 University Of Illinois Foundaton Fluorescent derivatives of adenine-containing compounds
US3893998A (en) * 1973-02-22 1975-07-08 Univ Illinois Fluorescent derivatives of cytosine-containing compounds
US4816570A (en) * 1982-11-30 1989-03-28 The Board Of Regents Of The University Of Texas System Biologically reversible phosphate and phosphonate protective groups
US5159067A (en) * 1987-01-28 1992-10-27 University Of Georgia Research Foundation Inc. 5'-Diphosphohexose nucleoside pharmaceutical compositions
US5118672A (en) * 1989-07-10 1992-06-02 University Of Georgia Research Foundation 5'-diphosphohexose nucleoside pharmaceutical compositions
JPH04178328A (en) * 1990-11-08 1992-06-25 Unitika Ltd Vascularization-inhibitory agent
US6303774B1 (en) 1999-08-20 2001-10-16 Sri International Nucleoside pyrophosphate and triphosphate analogs and related compounds

Also Published As

Publication number Publication date
US3701772A (en) 1972-10-31
CA931141A (en) 1973-07-31
FR2051064A5 (en) 1971-04-02
JPS4910674B1 (en) 1974-03-12

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PE20 Patent expired after termination of 20 years