GB1314191A - Oestratrienes - Google Patents
OestratrienesInfo
- Publication number
- GB1314191A GB1314191A GB1099570A GB1314191DA GB1314191A GB 1314191 A GB1314191 A GB 1314191A GB 1099570 A GB1099570 A GB 1099570A GB 1314191D A GB1314191D A GB 1314191DA GB 1314191 A GB1314191 A GB 1314191A
- Authority
- GB
- United Kingdom
- Prior art keywords
- methoxy
- compounds
- prepared
- hydroxy
- trien
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001875 compounds Chemical class 0.000 abstract 8
- 238000006356 dehydrogenation reaction Methods 0.000 abstract 3
- -1 1H-tetrazolyl Chemical group 0.000 abstract 2
- DKGAVHZHDRPRBM-UHFFFAOYSA-N Tert-Butanol Chemical compound CC(C)(C)O DKGAVHZHDRPRBM-UHFFFAOYSA-N 0.000 abstract 2
- 238000006359 acetalization reaction Methods 0.000 abstract 2
- 238000006243 chemical reaction Methods 0.000 abstract 2
- 238000006114 decarboxylation reaction Methods 0.000 abstract 2
- 238000006266 etherification reaction Methods 0.000 abstract 2
- 230000007062 hydrolysis Effects 0.000 abstract 2
- 238000006460 hydrolysis reaction Methods 0.000 abstract 2
- JGJLWPGRMCADHB-UHFFFAOYSA-N hypobromite Chemical compound Br[O-] JGJLWPGRMCADHB-UHFFFAOYSA-N 0.000 abstract 2
- 230000003647 oxidation Effects 0.000 abstract 2
- 238000007254 oxidation reaction Methods 0.000 abstract 2
- HXITXNWTGFUOAU-UHFFFAOYSA-N phenylboronic acid Chemical compound OB(O)C1=CC=CC=C1 HXITXNWTGFUOAU-UHFFFAOYSA-N 0.000 abstract 2
- CCTRXAGOZHAIIB-PSBWJHGTSA-N (8R,9S,13R,14R)-17-hydrazinylidene-3-methoxy-13-methyl-6,7,8,9,11,12,15,16-octahydrocyclopenta[a]phenanthren-14-ol Chemical compound COC1=CC=2CC[C@H]3[C@@]4(CCC([C@@]4(C)CC[C@@H]3C2C=C1)=NN)O CCTRXAGOZHAIIB-PSBWJHGTSA-N 0.000 abstract 1
- DBXMWOATVSEFMD-PSBWJHGTSA-N (8r,9s,13s,14r)-14-hydroxy-3-methoxy-13-methyl-6,7,8,9,11,12,15,16-octahydrocyclopenta[a]phenanthren-17-one Chemical compound C1C[C@]2(C)C(=O)CC[C@@]2(O)[C@@H]2CCC3=CC(OC)=CC=C3[C@H]21 DBXMWOATVSEFMD-PSBWJHGTSA-N 0.000 abstract 1
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 abstract 1
- MPUPNGGHOORGNP-UHFFFAOYSA-N 2-(1,3-oxazol-2-yloxy)-1,3-oxazole Chemical compound N=1C=COC=1OC1=NC=CO1 MPUPNGGHOORGNP-UHFFFAOYSA-N 0.000 abstract 1
- PNZVFASWDSMJER-UHFFFAOYSA-N acetic acid;lead Chemical compound [Pb].CC(O)=O PNZVFASWDSMJER-UHFFFAOYSA-N 0.000 abstract 1
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 1
- 125000005073 adamantyl group Chemical group C12(CC3CC(CC(C1)C3)C2)* 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001340 alkali metals Chemical class 0.000 abstract 1
- 238000005899 aromatization reaction Methods 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- VAYGXNSJCAHWJZ-UHFFFAOYSA-N dimethyl sulfate Chemical compound COS(=O)(=O)OC VAYGXNSJCAHWJZ-UHFFFAOYSA-N 0.000 abstract 1
- 230000032050 esterification Effects 0.000 abstract 1
- 238000005886 esterification reaction Methods 0.000 abstract 1
- 230000001076 estrogenic effect Effects 0.000 abstract 1
- 125000002541 furyl group Chemical group 0.000 abstract 1
- 230000000871 hypocholesterolemic effect Effects 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003431 steroids Chemical class 0.000 abstract 1
- 125000001544 thienyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/0026—Oxygen-containing hetero ring cyclic ketals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1099570 | 1970-03-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1314191A true GB1314191A (en) | 1973-04-18 |
Family
ID=9978105
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1099570A Expired GB1314191A (en) | 1970-03-06 | 1970-03-06 | Oestratrienes |
Country Status (15)
| Country | Link |
|---|---|
| AT (3) | AT323340B (de) |
| BE (1) | BE763894A (de) |
| CA (1) | CA934366A (de) |
| CH (2) | CH583256A5 (de) |
| DE (1) | DE2110577A1 (de) |
| DK (1) | DK127419B (de) |
| ES (1) | ES388946A1 (de) |
| FR (1) | FR2085680B1 (de) |
| GB (1) | GB1314191A (de) |
| HU (1) | HU162819B (de) |
| IE (1) | IE35107B1 (de) |
| IL (1) | IL36355A0 (de) |
| NL (1) | NL7103015A (de) |
| SE (1) | SE369189B (de) |
| ZA (1) | ZA711434B (de) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL6703781A (de) * | 1967-03-13 | 1968-09-16 | ||
| GB1278705A (en) * | 1968-09-11 | 1972-06-21 | Koninklijke Gist Spiritus | Oestratrienes |
-
1970
- 1970-03-06 GB GB1099570A patent/GB1314191A/en not_active Expired
-
1971
- 1971-03-05 NL NL7103015A patent/NL7103015A/xx unknown
- 1971-03-05 ES ES388946A patent/ES388946A1/es not_active Expired
- 1971-03-05 ZA ZA711434A patent/ZA711434B/xx unknown
- 1971-03-05 CH CH3265716A patent/CH583256A5/xx not_active IP Right Cessation
- 1971-03-05 AT AT190471A patent/AT323340B/de not_active IP Right Cessation
- 1971-03-05 AT AT552172A patent/AT316770B/de not_active IP Right Cessation
- 1971-03-05 DE DE19712110577 patent/DE2110577A1/de active Pending
- 1971-03-05 HU HUKO2409A patent/HU162819B/hu unknown
- 1971-03-05 BE BE763894A patent/BE763894A/xx unknown
- 1971-03-05 AT AT551972A patent/AT323906B/de not_active IP Right Cessation
- 1971-03-05 CA CA107001A patent/CA934366A/en not_active Expired
- 1971-03-05 DK DK105271AA patent/DK127419B/da unknown
- 1971-03-05 CH CH326571A patent/CH582199A5/xx not_active IP Right Cessation
- 1971-03-05 IE IE273/71A patent/IE35107B1/xx unknown
- 1971-03-05 IL IL36355A patent/IL36355A0/xx unknown
- 1971-03-05 FR FR7107789A patent/FR2085680B1/fr not_active Expired
- 1971-03-05 SE SE02842/71A patent/SE369189B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL36355A0 (en) | 1971-05-26 |
| ZA711434B (en) | 1971-11-24 |
| CA934366A (en) | 1973-09-25 |
| ES388946A1 (es) | 1973-05-01 |
| BE763894A (fr) | 1971-09-06 |
| DE2110577A1 (de) | 1971-09-16 |
| CH582199A5 (de) | 1976-11-30 |
| DK127419B (da) | 1973-11-05 |
| FR2085680B1 (de) | 1975-08-01 |
| HU162819B (de) | 1973-04-28 |
| AT316770B (de) | 1974-07-25 |
| FR2085680A1 (de) | 1971-12-31 |
| IE35107B1 (en) | 1975-11-12 |
| CH583256A5 (de) | 1976-12-31 |
| AT323906B (de) | 1975-08-11 |
| SE369189B (de) | 1974-08-12 |
| IE35107L (en) | 1971-09-06 |
| AT323340B (de) | 1975-07-10 |
| NL7103015A (de) | 1971-09-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |