GB1311956A - Method of potentiating the activity of phosphonomycin antibiotics - Google Patents
Method of potentiating the activity of phosphonomycin antibioticsInfo
- Publication number
- GB1311956A GB1311956A GB4606370A GB4606370A GB1311956A GB 1311956 A GB1311956 A GB 1311956A GB 4606370 A GB4606370 A GB 4606370A GB 4606370 A GB4606370 A GB 4606370A GB 1311956 A GB1311956 A GB 1311956A
- Authority
- GB
- United Kingdom
- Prior art keywords
- phosphonomycin
- bacteria
- antibiotics
- activity
- potentiating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- YMDXZJFXQJVXBF-STHAYSLISA-N fosfomycin Chemical compound C[C@@H]1O[C@@H]1P(O)(O)=O YMDXZJFXQJVXBF-STHAYSLISA-N 0.000 title abstract 5
- 239000003242 anti bacterial agent Substances 0.000 title abstract 2
- 229940088710 antibiotic agent Drugs 0.000 title abstract 2
- 230000000694 effects Effects 0.000 title 1
- 230000003389 potentiating effect Effects 0.000 title 1
- 241000894006 Bacteria Species 0.000 abstract 3
- 230000003115 biocidal effect Effects 0.000 abstract 2
- 239000000411 inducer Substances 0.000 abstract 2
- 230000037361 pathway Effects 0.000 abstract 2
- 229910019142 PO4 Inorganic materials 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 235000021317 phosphate Nutrition 0.000 abstract 1
- 150000003013 phosphoric acid derivatives Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 150000005846 sugar alcohols Polymers 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/665—Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/18—Testing for antimicrobial activity of a material
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Toxicology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86335169A | 1969-10-02 | 1969-10-02 | |
| US7124770A | 1970-09-11 | 1970-09-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1311956A true GB1311956A (en) | 1973-03-28 |
Family
ID=26752007
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4606370A Expired GB1311956A (en) | 1969-10-02 | 1970-09-28 | Method of potentiating the activity of phosphonomycin antibiotics |
Country Status (7)
| Country | Link |
|---|---|
| BE (1) | BE756953A (enrdf_load_stackoverflow) |
| CA (1) | CA943067A (enrdf_load_stackoverflow) |
| DE (1) | DE2048375A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2070104B1 (enrdf_load_stackoverflow) |
| GB (1) | GB1311956A (enrdf_load_stackoverflow) |
| IL (1) | IL35334A (enrdf_load_stackoverflow) |
| NL (1) | NL7014541A (enrdf_load_stackoverflow) |
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT383736B (de) * | 1984-10-05 | 1987-08-10 | Schering Spa | Verfahren zur herstellung von wasserloeslichen pharmazeutischen zusammensetzungen |
| AT383735B (de) * | 1984-10-05 | 1987-08-10 | Schering Spa | Verfahren zur herstellung von wasserloeslichen pharmazeutischen zusammensetzungen |
| US5520926A (en) * | 1992-03-17 | 1996-05-28 | British Technology Group Limited | Method of using mannose phosphates for the treatment of fibrotic disorders |
| GB2299025A (en) * | 1992-03-17 | 1996-09-25 | British Tech Group | Formulations of mannose phosphates useful in the treatment of fibrotic disorders |
| US7470699B2 (en) | 2003-07-11 | 2008-12-30 | Arena Pharmaceuticals, Inc. | Trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto |
| US7812159B2 (en) | 2005-01-10 | 2010-10-12 | Arena Pharamaceuticals, Inc. | Processes for preparing aromatic ethers |
| US8293751B2 (en) | 2003-01-14 | 2012-10-23 | Arena Pharmaceuticals, Inc. | 1,2,3-trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto such as diabetes and hyperglycemia |
| US8362248B2 (en) | 2005-01-10 | 2013-01-29 | Arena Pharmaceuticals, Inc. | Substituted pyridinyl and pyrimidinyl derivatives as modulators of metabolism and the treatment of disorders related thereto |
| US10894787B2 (en) | 2010-09-22 | 2021-01-19 | Arena Pharmaceuticals, Inc. | Modulators of the GPR119 receptor and the treatment of disorders related thereto |
| US11007175B2 (en) | 2015-01-06 | 2021-05-18 | Arena Pharmaceuticals, Inc. | Methods of treating conditions related to the S1P1 receptor |
| US11884626B2 (en) | 2015-06-22 | 2024-01-30 | Arena Pharmaceuticals, Inc. | Crystalline L-arginine salt of (R)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclo-penta [b]indol-3-yl)acetic acid(Compound1) for use in S1P1 receptor-associated disorders |
| US12156866B2 (en) | 2018-06-06 | 2024-12-03 | Arena Pharmaceuticals, Inc. | Methods of treating conditions related to the S1P1 receptor |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110520124A (zh) | 2017-02-16 | 2019-11-29 | 艾尼纳制药公司 | 用于治疗原发性胆汁性胆管炎的化合物和方法 |
-
0
- BE BE756953D patent/BE756953A/xx unknown
-
1970
- 1970-09-22 IL IL35334A patent/IL35334A/xx unknown
- 1970-09-28 GB GB4606370A patent/GB1311956A/en not_active Expired
- 1970-10-01 CA CA095,832A patent/CA943067A/en not_active Expired
- 1970-10-01 FR FR707035490A patent/FR2070104B1/fr not_active Expired
- 1970-10-01 DE DE19702048375 patent/DE2048375A1/de active Pending
- 1970-10-02 NL NL7014541A patent/NL7014541A/xx unknown
Cited By (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT383736B (de) * | 1984-10-05 | 1987-08-10 | Schering Spa | Verfahren zur herstellung von wasserloeslichen pharmazeutischen zusammensetzungen |
| AT383735B (de) * | 1984-10-05 | 1987-08-10 | Schering Spa | Verfahren zur herstellung von wasserloeslichen pharmazeutischen zusammensetzungen |
| US5520926A (en) * | 1992-03-17 | 1996-05-28 | British Technology Group Limited | Method of using mannose phosphates for the treatment of fibrotic disorders |
| GB2265310B (en) * | 1992-03-17 | 1996-09-25 | British Tech Group | Treatment of fibrotic disorders with mannose phosphates |
| GB2299025A (en) * | 1992-03-17 | 1996-09-25 | British Tech Group | Formulations of mannose phosphates useful in the treatment of fibrotic disorders |
| GB2299025B (en) * | 1992-03-17 | 1996-11-27 | British Tech Group | Dispenser containing a formulation of mannose phosphate useful in the treatment of fibrotic disorders of the eye |
| US8933083B2 (en) | 2003-01-14 | 2015-01-13 | Arena Pharmaceuticals, Inc. | 1,2,3-trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto such as diabetes and hyperglycemia |
| US8293751B2 (en) | 2003-01-14 | 2012-10-23 | Arena Pharmaceuticals, Inc. | 1,2,3-trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto such as diabetes and hyperglycemia |
| US7838525B2 (en) | 2003-07-11 | 2010-11-23 | Arena Pharmaceuticals, Inc. | Trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto |
| US8546429B2 (en) | 2003-07-11 | 2013-10-01 | Arena Pharmaceuticals, Inc. | 1,2,3-trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto |
| US7470699B2 (en) | 2003-07-11 | 2008-12-30 | Arena Pharmaceuticals, Inc. | Trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto |
| US7812159B2 (en) | 2005-01-10 | 2010-10-12 | Arena Pharamaceuticals, Inc. | Processes for preparing aromatic ethers |
| US8362248B2 (en) | 2005-01-10 | 2013-01-29 | Arena Pharmaceuticals, Inc. | Substituted pyridinyl and pyrimidinyl derivatives as modulators of metabolism and the treatment of disorders related thereto |
| US10894787B2 (en) | 2010-09-22 | 2021-01-19 | Arena Pharmaceuticals, Inc. | Modulators of the GPR119 receptor and the treatment of disorders related thereto |
| US11007175B2 (en) | 2015-01-06 | 2021-05-18 | Arena Pharmaceuticals, Inc. | Methods of treating conditions related to the S1P1 receptor |
| US11884626B2 (en) | 2015-06-22 | 2024-01-30 | Arena Pharmaceuticals, Inc. | Crystalline L-arginine salt of (R)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclo-penta [b]indol-3-yl)acetic acid(Compound1) for use in S1P1 receptor-associated disorders |
| US12156866B2 (en) | 2018-06-06 | 2024-12-03 | Arena Pharmaceuticals, Inc. | Methods of treating conditions related to the S1P1 receptor |
Also Published As
| Publication number | Publication date |
|---|---|
| CA943067A (en) | 1974-03-05 |
| BE756953A (fr) | 1971-04-01 |
| IL35334A (en) | 1974-01-14 |
| FR2070104A1 (enrdf_load_stackoverflow) | 1971-09-10 |
| DE2048375A1 (de) | 1971-04-22 |
| FR2070104B1 (enrdf_load_stackoverflow) | 1974-02-22 |
| IL35334A0 (en) | 1971-04-28 |
| NL7014541A (enrdf_load_stackoverflow) | 1971-04-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |