GB1305216A - - Google Patents

Info

Publication number
GB1305216A
GB1305216A GB5379970A GB5379970A GB1305216A GB 1305216 A GB1305216 A GB 1305216A GB 5379970 A GB5379970 A GB 5379970A GB 5379970 A GB5379970 A GB 5379970A GB 1305216 A GB1305216 A GB 1305216A
Authority
GB
United Kingdom
Prior art keywords
alkyl
nov
cycloalkyl
hydrogen
isoxazole
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB5379970A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of GB1305216A publication Critical patent/GB1305216A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/18—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

1305216 Isoxazole derivatives SHIONOGI & CO Ltd 12 Nov 1970 [12 Nov 1969] 53799/70 Heading C2C Novel isoxazole derivatives of the general Formula I wherein R<SP>1</SP> and R<SP>2</SP> are the same or different and are each hydrogen, C 1-8 alkyl or cycloalkyl; R<SP>3</SP> and R<SP>4</SP> are the same or different and are each hydrogen, C 1-8 alkyl, cycloalkyl, or (C 1-8 ) alkyl, aryl or when taken together with the adjacent nitrogen are pyrrolidino, piperidino, piperazino or morpholino; and Y is oxygen, sulphur or imino may be prepared by reacting a derivativof an isoxazole-3-carboxylic acid II or a derivae tive thereof with a urea, thiourea or guanide of the Formula III Pharmaceutical compositions cf the compounds I with the usual excipients show hypoglycemic activity when administered orally or parenterally.
GB5379970A 1969-11-12 1970-11-12 Expired GB1305216A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9061969 1969-11-12

Publications (1)

Publication Number Publication Date
GB1305216A true GB1305216A (en) 1973-01-31

Family

ID=14003488

Family Applications (1)

Application Number Title Priority Date Filing Date
GB5379970A Expired GB1305216A (en) 1969-11-12 1970-11-12

Country Status (12)

Country Link
AT (1) AT307440B (en)
BE (1) BE758762A (en)
CA (1) CA952524A (en)
CH (1) CH553806A (en)
DE (1) DE2055727A1 (en)
ES (1) ES385435A1 (en)
FR (1) FR2073340B1 (en)
GB (1) GB1305216A (en)
NL (1) NL7016613A (en)
SE (1) SE361041B (en)
SU (1) SU383299A3 (en)
ZA (1) ZA707544B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4163784A (en) 1978-03-09 1979-08-07 Pfizer Inc. Heterocyclylcarbonyl derivatives of urea, agents for dissolution of gallstones
DE4412334A1 (en) * 1994-04-11 1995-10-19 Hoechst Ag Substituted N-heteroaroylguanidines, process for their preparation, their use as a medicament or diagnostic agent, and medicament containing them

Also Published As

Publication number Publication date
SU383299A3 (en) 1973-05-25
SE361041B (en) 1973-10-15
FR2073340B1 (en) 1974-06-21
CH553806A (en) 1974-09-13
ZA707544B (en) 1971-07-28
NL7016613A (en) 1971-05-14
FR2073340A1 (en) 1971-10-01
AT307440B (en) 1973-04-15
CA952524A (en) 1974-08-06
ES385435A1 (en) 1973-04-16
DE2055727A1 (en) 1971-05-19
BE758762A (en) 1971-04-16

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee