GB1304633A - - Google Patents
Info
- Publication number
- GB1304633A GB1304633A GB1794471A GB1794471A GB1304633A GB 1304633 A GB1304633 A GB 1304633A GB 1794471 A GB1794471 A GB 1794471A GB 1794471 A GB1794471 A GB 1794471A GB 1304633 A GB1304633 A GB 1304633A
- Authority
- GB
- United Kingdom
- Prior art keywords
- ajmalicine
- hydroxyajmalicine
- diazomethane
- hypotensive
- methylation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- YXHKONLOYHBTNS-UHFFFAOYSA-N Diazomethane Chemical compound C=[N+]=[N-] YXHKONLOYHBTNS-UHFFFAOYSA-N 0.000 abstract 1
- 208000001953 Hypotension Diseases 0.000 abstract 1
- YWULOMNQOWMRFL-UHFFFAOYSA-N O-demethyl-cabucine Natural products C1=C(O)C=C2C(CCN3CC4C(C)OC=C(C4CC33)C(=O)OC)=C3NC2=C1 YWULOMNQOWMRFL-UHFFFAOYSA-N 0.000 abstract 1
- GRTOGORTSDXSFK-XJTZBENFSA-N ajmalicine Chemical class C1=CC=C2C(CCN3C[C@@H]4[C@H](C)OC=C([C@H]4C[C@H]33)C(=O)OC)=C3NC2=C1 GRTOGORTSDXSFK-XJTZBENFSA-N 0.000 abstract 1
- 229940007897 ajmalicine Drugs 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 208000021822 hypotensive Diseases 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
- 230000011987 methylation Effects 0.000 abstract 1
- 238000007069 methylation reaction Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000000304 vasodilatating effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR707019975A FR2092608B1 (enrdf_load_stackoverflow) | 1970-06-01 | 1970-06-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1304633A true GB1304633A (enrdf_load_stackoverflow) | 1973-01-24 |
Family
ID=9056473
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1794471A Expired GB1304633A (enrdf_load_stackoverflow) | 1970-06-01 | 1971-05-28 |
Country Status (9)
| Country | Link |
|---|---|
| AT (1) | AT306257B (enrdf_load_stackoverflow) |
| BE (1) | BE767773A (enrdf_load_stackoverflow) |
| CH (1) | CH538505A (enrdf_load_stackoverflow) |
| DE (1) | DE2126465A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2092608B1 (enrdf_load_stackoverflow) |
| GB (1) | GB1304633A (enrdf_load_stackoverflow) |
| NL (1) | NL7107300A (enrdf_load_stackoverflow) |
| SU (1) | SU441708A3 (enrdf_load_stackoverflow) |
| ZA (1) | ZA713411B (enrdf_load_stackoverflow) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9316352D0 (en) * | 1993-08-06 | 1993-09-22 | Erba Carlo Spa | Process for the preparation of 9-amino camptothecin |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1115417A (en) * | 1967-02-10 | 1968-05-29 | Boehringer & Soehne Gmbh | Compositions containing raubasine and a new method of using raubasine |
-
1970
- 1970-06-01 FR FR707019975A patent/FR2092608B1/fr not_active Expired
-
1971
- 1971-05-26 ZA ZA713411A patent/ZA713411B/xx unknown
- 1971-05-27 DE DE19712126465 patent/DE2126465A1/de active Pending
- 1971-05-27 BE BE767773A patent/BE767773A/xx unknown
- 1971-05-27 NL NL7107300A patent/NL7107300A/xx unknown
- 1971-05-28 AT AT466671A patent/AT306257B/de not_active IP Right Cessation
- 1971-05-28 CH CH787471A patent/CH538505A/fr not_active IP Right Cessation
- 1971-05-28 GB GB1794471A patent/GB1304633A/en not_active Expired
- 1971-05-31 SU SU1659440A patent/SU441708A3/ru active
Also Published As
| Publication number | Publication date |
|---|---|
| ZA713411B (en) | 1972-01-26 |
| CH538505A (fr) | 1973-06-30 |
| BE767773A (enrdf_load_stackoverflow) | 1971-11-29 |
| FR2092608B1 (enrdf_load_stackoverflow) | 1973-08-10 |
| SU441708A3 (ru) | 1974-08-30 |
| AT306257B (de) | 1973-04-10 |
| FR2092608A1 (enrdf_load_stackoverflow) | 1972-01-28 |
| NL7107300A (enrdf_load_stackoverflow) | 1971-12-03 |
| DE2126465A1 (de) | 1971-12-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| CSNS | Application of which complete specification have been accepted and published, but patent is not sealed |