GB1284947A - Improved lyophilized erythrocyte composition - Google Patents

Improved lyophilized erythrocyte composition

Info

Publication number
GB1284947A
GB1284947A GB21681/70A GB2168170A GB1284947A GB 1284947 A GB1284947 A GB 1284947A GB 21681/70 A GB21681/70 A GB 21681/70A GB 2168170 A GB2168170 A GB 2168170A GB 1284947 A GB1284947 A GB 1284947A
Authority
GB
United Kingdom
Prior art keywords
volume
erythrocytes
preparation
serum albumin
pretreated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB21681/70A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of GB1284947A publication Critical patent/GB1284947A/en
Expired legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/554—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being a biological cell or cell fragment, e.g. bacteria, yeast cells
    • G01N33/555—Red blood cell
    • G01N33/556—Fixed or stabilised red blood cell
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0205—Chemical aspects
    • A01N1/0231—Chemically defined matrices, e.g. alginate gels, for immobilising, holding or storing cells, tissue or organs for preservation purposes; Chemically altering or fixing cells, tissue or organs, e.g. by cross-linking, for preservation purposes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/18—Erythrocytes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Food Science & Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Dispersion Chemistry (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Environmental Sciences (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

1284947 Erythrocyte preparation; immunological reagent ABBOTT LABORATORIES 5 May 1970 [27 May 1969] 21681/70 Addition to 1244344 Heading B1X An aqueous erythrocyte preparation which can be lyophilized and reconstituted for use comprises a suspension of 0.1% to 10% by volume erythrocytes which have been pretreated with (a) a minor volume of pyruvic aldehyde relative to their volume, and (b) a minor volume of formaldehyde relative to their volume, the suspension also containing 0.1% to 1% by weight blood serum albumin and 5% to 30% by weight of sucrose, lactose or a mixture thereof. The erythrocytes may be rabbit, rat, pigeon, sheep, chicken or human cells. The serum albumin may be bovine, rabbit or chicken. The erythrocytes to be used in the preparation may be stored in pretreated form, before or after coating with antigen and/or potentiation as in Parent Specification. In an Example the pretreated erythrocytes are coated with bovine serum albumin before use in the preparation.
GB21681/70A 1969-05-27 1970-05-05 Improved lyophilized erythrocyte composition Expired GB1284947A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US82835769A 1969-05-27 1969-05-27

Publications (1)

Publication Number Publication Date
GB1284947A true GB1284947A (en) 1972-08-09

Family

ID=25251578

Family Applications (1)

Application Number Title Priority Date Filing Date
GB21681/70A Expired GB1284947A (en) 1969-05-27 1970-05-05 Improved lyophilized erythrocyte composition

Country Status (5)

Country Link
JP (1) JPS4921052B1 (en)
CH (1) CH526960A (en)
ES (1) ES380066A2 (en)
FR (1) FR2043696A6 (en)
GB (1) GB1284947A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4403037A (en) 1980-10-10 1983-09-06 American Hoechst Corporation Erythrocyte preparations and use thereof in hemagglutination tests
CN115399314A (en) * 2022-11-01 2022-11-29 天津德祥生物技术股份有限公司 Human ABO blood type anti-typing red blood cells capable of being freeze-dried and stored and storage method

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2016687B (en) * 1978-03-20 1982-09-08 Abbott Lab Sugar coated reagents for solid phase immunoassay
JPS5917388B2 (en) * 1979-02-22 1984-04-20 富士レビオ株式会社 Absorbent for indirect flocculation reaction
FR2475737A1 (en) * 1980-02-07 1981-08-14 Pasteur Institut Preservation of red blood corpuscles - suitable for use as haemagglutination standards, by aldehyde treatment and lyophilisation
JPH08192679A (en) * 1995-01-17 1996-07-30 Takao Ishikawa Auxiliary mirror fitted to rear glass of automobile

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4403037A (en) 1980-10-10 1983-09-06 American Hoechst Corporation Erythrocyte preparations and use thereof in hemagglutination tests
CN115399314A (en) * 2022-11-01 2022-11-29 天津德祥生物技术股份有限公司 Human ABO blood type anti-typing red blood cells capable of being freeze-dried and stored and storage method

Also Published As

Publication number Publication date
FR2043696A6 (en) 1971-02-19
CH526960A (en) 1972-08-31
ES380066A2 (en) 1972-08-16
JPS4921052B1 (en) 1974-05-29

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee