GB1277268A - 6-substituted-13-polycarbonalkyl-18,19-dinorpregna-3,5-dienes - Google Patents

6-substituted-13-polycarbonalkyl-18,19-dinorpregna-3,5-dienes

Info

Publication number
GB1277268A
GB1277268A GB32415/71A GB3241571A GB1277268A GB 1277268 A GB1277268 A GB 1277268A GB 32415/71 A GB32415/71 A GB 32415/71A GB 3241571 A GB3241571 A GB 3241571A GB 1277268 A GB1277268 A GB 1277268A
Authority
GB
United Kingdom
Prior art keywords
polycarbonalkyl
dinorpregna
dienes
substituted
cho
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB32415/71A
Inventor
George Henry Douglas
Herchel Smith
Daniel Myron Teller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
American Home Products Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Products Corp filed Critical American Home Products Corp
Publication of GB1277268A publication Critical patent/GB1277268A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms

Abstract

1277268 6 - Substituted - 13 - polycarbonalkyl - -18,19 - dinorpregna - 3,5 - dienes AMERICAN HOME PRODUCTS CORP 30 July 1969 [30 July 1968 19 May 1969] 32415/71 Divided out of 1277265 Heading C2U Novel steroids of the formula (wherein R is C 2-6 alkyl; X is CO or CHOR<SP>1</SP> in which R<SP>1</SP> is H, HCO or C 2-7 alkanoyl; Y is H, OH or C 2-7 alkanoyloxy; W is alkoxy; and V is CH 2 OH or CHO) are prepared by formylating steroids of the formula (wherein there are double bonds in the 2- and 5(10)- or the 3- and 5-positions) to give products wherein V is CHO and, when required, selectively reducing these to give products wherein V is CH 2 OH. 20-Acylates may be selectively hydrolysed to 20-ols.
GB32415/71A 1968-07-30 1969-07-30 6-substituted-13-polycarbonalkyl-18,19-dinorpregna-3,5-dienes Expired GB1277268A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US74860668A 1968-07-30 1968-07-30
US82597469A 1969-05-19 1969-05-19

Publications (1)

Publication Number Publication Date
GB1277268A true GB1277268A (en) 1972-06-07

Family

ID=27114971

Family Applications (2)

Application Number Title Priority Date Filing Date
GB32415/71A Expired GB1277268A (en) 1968-07-30 1969-07-30 6-substituted-13-polycarbonalkyl-18,19-dinorpregna-3,5-dienes
GB38168/69A Expired GB1277265A (en) 1968-07-30 1969-07-30 6-substituted-13-polycarbonalkyl-18,19-dinorpregn-4-en-3-ones

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB38168/69A Expired GB1277265A (en) 1968-07-30 1969-07-30 6-substituted-13-polycarbonalkyl-18,19-dinorpregn-4-en-3-ones

Country Status (8)

Country Link
JP (1) JPS4830050B1 (en)
BE (1) BE736833A (en)
BR (1) BR6911184D0 (en)
DE (1) DE1938283A1 (en)
FR (1) FR2014016A1 (en)
GB (2) GB1277268A (en)
IL (1) IL32699A (en)
NL (1) NL6911649A (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0321292A (en) * 1989-06-17 1991-01-30 Masaru Nakayama Bobbin thread winding device of sewing machine
WO2001058919A2 (en) * 2000-02-11 2001-08-16 Sri International Synthesis of anti-estrogenic and other therapeutic steroids from 21-hydroxy-19-norpregna-4-en-3-one
DE102007027636A1 (en) * 2007-06-12 2008-12-18 Bayer Schering Pharma Aktiengesellschaft 17β-Cyano-18α-homo-19-nor-androst-4-ene derivative, its use and the derivative-containing drug

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3402173A (en) * 1965-03-19 1968-09-17 Syntex Corp 18-lower alkyl pregnanes and derivatives

Also Published As

Publication number Publication date
IL32699A (en) 1973-06-29
IL32699A0 (en) 1969-09-25
FR2014016A1 (en) 1970-04-10
GB1277265A (en) 1972-06-07
BR6911184D0 (en) 1973-03-13
DE1938283A1 (en) 1970-02-05
BE736833A (en) 1970-01-30
JPS4830050B1 (en) 1973-09-17
NL6911649A (en) 1970-02-03

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PE20 Patent expired after termination of 20 years