GB1253756A - New derivatives of nicotinic acid and methods for their preparation - Google Patents

New derivatives of nicotinic acid and methods for their preparation

Info

Publication number
GB1253756A
GB1253756A GB3677369A GB3677369A GB1253756A GB 1253756 A GB1253756 A GB 1253756A GB 3677369 A GB3677369 A GB 3677369A GB 3677369 A GB3677369 A GB 3677369A GB 1253756 A GB1253756 A GB 1253756A
Authority
GB
United Kingdom
Prior art keywords
nicotinic acid
hydroxymethyl
tris
derivative
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3677369A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medisan AB
Original Assignee
Medisan AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medisan AB filed Critical Medisan AB
Publication of GB1253756A publication Critical patent/GB1253756A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1,253,756. Derivatives of nicotinic acid. MEDISAN A.B. 22 July, 1969 [22 July, 1968], No. 36773/69. Heading C2C. Novel derivatives of nicotinic acid of the formula wherein R is a nicotinoyl radical and x is 1 to 4 and physiologically acceptable acid addition salts thereof are prepared reacting 1 mole of tris- (hydroxymethyl)-aminomethane with x moles of nicotinic acid or reactive derivative thereof, or by reacting tris-(hydroxymethyl)nitromethane with 1 to 3 moles of nicotinic acid or reactive derivative and reducing the acylated derivative thus obtained, or by acylating a tris(hydroxymethyl)aminomethane derivative in which one or more of the active hydrogen atoms have been protected by formation of acetals and removing the acetal groups from the resulting compounds.
GB3677369A 1968-07-22 1969-07-22 New derivatives of nicotinic acid and methods for their preparation Expired GB1253756A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE998968A SE349029B (en) 1968-07-22 1968-07-22

Publications (1)

Publication Number Publication Date
GB1253756A true GB1253756A (en) 1971-11-17

Family

ID=20277973

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3677369A Expired GB1253756A (en) 1968-07-22 1969-07-22 New derivatives of nicotinic acid and methods for their preparation

Country Status (8)

Country Link
JP (1) JPS5016359B1 (en)
BE (1) BE736133A (en)
DE (1) DE1936344A1 (en)
DK (1) DK126502B (en)
FR (1) FR2013448A1 (en)
GB (1) GB1253756A (en)
NL (1) NL6910800A (en)
SE (1) SE349029B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5811592U (en) * 1981-07-15 1983-01-25 日立化成工業株式会社 Insect-proof packing for kitchen furniture

Also Published As

Publication number Publication date
SE349029B (en) 1972-09-18
NL6910800A (en) 1970-01-26
DK126502B (en) 1973-07-23
FR2013448A1 (en) 1970-04-03
BE736133A (en) 1970-01-15
JPS5016359B1 (en) 1975-06-12
DE1936344A1 (en) 1970-01-22

Similar Documents

Publication Publication Date Title
GB1213162A (en) Serum lipid lowering pyridine derivatives and their preparation
ES8506629A1 (en) Pyridine derivatives.
GB1180304A (en) Preparation of Nucleoside-5'-Polyphosphates and their Nucleotidyl Derivatives
GB1171156A (en) Improvements in or relating to Cycloalkane Derivatives and the Manufacture thereof
ES421430A1 (en) Carbostyril derivatives and process for preparing the same
GB1253756A (en) New derivatives of nicotinic acid and methods for their preparation
GB1164108A (en) Desglucohellebrin Derivatives
ES411112A1 (en) Anti-inflammatory agents and method for their preparation
GB1212174A (en) Process for the production of new 2-oxo-1,2-dihydroquinoline derivatives
ES414136A1 (en) Preparation of 1,2-dichloro-3-amino propane derivatives
GB1419028A (en) Process for production of 2-hydroxymethyl pyridine derivatives
GB1204967A (en) Organic phosphorus compounds, their production and use
ES8504252A1 (en) Novel anthracycline derivatives, a process for preparing the same by a microorganism strain, the novel strain streptomyces cyaneus, and use of the anthracycline derivatives as medicaments.
GB1265824A (en)
GB1164699A (en) Production of Pyrone Derivatives
GB1192126A (en) Indole Derivatives and their production
GB1422216A (en) Phenyl-formamidine derivatives
ES8602764A1 (en) Aminothiadiazine derivatives as histamine H2-antagonists.
GB1130730A (en) New derivatives of [2-(5-nitrofuryl-2)-vinyl]-s-triazolo-[4.3-a]-pyridine and process for the preparation thereof
GB1271519A (en) Improvements in or relating to derivatives of phloroglucinol
GB1199699A (en) Process for the Production of Condensed Aromatic Bis-(2,4-Dihydroxypyridine) Derivatives
GB1261593A (en) Novel 3-arylimino-4-chloro-5-amino-1,2-dithioles, process for their production and compositions containing same
GB1165317A (en) (2-Propynyloxy)-Beta-Nitro-Styrenes and a Process for the Production of these Compounds
GB1411681A (en) Substituted phenylacetic acid esters and processes for their manufacture
GB1286198A (en) Cyclic acetal derivatives of pregnane and process for preparation thereof