GB1230127A - - Google Patents

Info

Publication number
GB1230127A
GB1230127A GB1230127DA GB1230127A GB 1230127 A GB1230127 A GB 1230127A GB 1230127D A GB1230127D A GB 1230127DA GB 1230127 A GB1230127 A GB 1230127A
Authority
GB
United Kingdom
Prior art keywords
protein
heptose
pentose
hexose
metal chelates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
Inventor
W Huber
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Diagnostic Data Inc
Original Assignee
Diagnostic Data Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Diagnostic Data Inc filed Critical Diagnostic Data Inc
Publication of GB1230127A publication Critical patent/GB1230127A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

It has been found that protein/metal chelates, as they can be obtained by the process described in Swiss Patent Application No. 575,433, can be stabilised when such protein/metal chelates, whose protein portion has at least one acidic and/or basic amino acid unit from the series comprising aspartic acid, glutamic acid, histidine, arginine and lysine, are treated with a hydroxyl-containing saccharide in the presence of a solvent. The saccharide used is either a sucrose, a pentose, hexose or heptose, a lower alkyl acetal of a pentose, hexose or heptose or a mannose.
GB1230127D 1967-08-02 1968-08-02 Expired GB1230127A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US65797167A 1967-08-02 1967-08-02

Publications (1)

Publication Number Publication Date
GB1230127A true GB1230127A (en) 1971-04-28

Family

ID=24639378

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1230127D Expired GB1230127A (en) 1967-08-02 1968-08-02

Country Status (12)

Country Link
JP (1) JPS5018056B1 (en)
AT (1) AT304764B (en)
BE (1) BE718887A (en)
CH (1) CH611316A5 (en)
DE (1) DE1792196C3 (en)
DK (1) DK131273B (en)
ES (1) ES356828A1 (en)
FR (1) FR8127M (en)
GB (1) GB1230127A (en)
IL (1) IL30448A (en)
NL (1) NL163720C (en)
SE (1) SE375009B (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0035204A2 (en) * 1980-03-05 1981-09-09 Miles Inc. Pasteurized therapeutically active protein compositions
EP0058993A2 (en) * 1981-02-25 1982-09-01 The Green Cross Corporation Process for heat treatment of aqueous solution containing cold insoluble globulin
EP0123375B1 (en) * 1983-02-25 1988-10-26 Green Cross Corporation Gamma-globulin preparation for intravenous administration
EP0352753A2 (en) * 1988-07-29 1990-01-31 Mercian Corporation Model kit for learning blood typing principle

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5920647B2 (en) * 1976-10-01 1984-05-15 武田薬品工業株式会社 injection
IL149778A0 (en) * 1999-11-22 2002-11-10 Universal Preservation Technologies Inc Preservation of sensitive biological material
US6872357B1 (en) 2000-11-22 2005-03-29 Quadrant Drug Delivery Limited Formulation of preservation mixtures containing sensitive biologicals to be stabilized for ambient temperature storage by drying

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0035204A2 (en) * 1980-03-05 1981-09-09 Miles Inc. Pasteurized therapeutically active protein compositions
EP0035204A3 (en) * 1980-03-05 1982-11-10 Miles Laboratories, Inc. Pasteurized therapeutically active protein compositions
DK156698B (en) * 1980-03-05 1989-09-25 Miles Inc PROCEDURE FOR PASTEURIZATION OF A MATERIAL CONTAINING A THERMALLALLY SENSITIVE, THERAPEUTIC ACTIVITY PROTEIN SELECTED WITH ALFA-L-ANTITRYPSIN, ANTITHROMOBIN-III, PRAEKALLIKRINE, ANTIHAEMOFILE FACTOR
EP0058993A2 (en) * 1981-02-25 1982-09-01 The Green Cross Corporation Process for heat treatment of aqueous solution containing cold insoluble globulin
EP0058993A3 (en) * 1981-02-25 1985-01-23 The Green Cross Corporation Process for heat treatment of aqueous solution containing cold insoluble globulin
EP0123375B1 (en) * 1983-02-25 1988-10-26 Green Cross Corporation Gamma-globulin preparation for intravenous administration
EP0352753A2 (en) * 1988-07-29 1990-01-31 Mercian Corporation Model kit for learning blood typing principle
EP0352753A3 (en) * 1988-07-29 1990-06-13 Mercian Corporation Model kit for learning blood typing principle

Also Published As

Publication number Publication date
DE1792196A1 (en) 1972-05-18
DK131273B (en) 1975-06-23
CH611316A5 (en) 1979-05-31
SE375009B (en) 1975-04-07
JPS5018056B1 (en) 1975-06-26
DE1792196B2 (en) 1980-08-14
IL30448A (en) 1972-06-28
NL163720B (en) 1980-05-16
DE1792196C3 (en) 1981-04-02
ES356828A1 (en) 1970-02-16
AT304764B (en) 1973-01-25
DK131273C (en) 1975-11-24
FR8127M (en) 1970-08-10
NL6811058A (en) 1969-02-04
BE718887A (en) 1969-01-31
IL30448A0 (en) 1968-09-26
NL163720C (en) 1980-10-15

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]