GB1229396A - - Google Patents

Info

Publication number
GB1229396A
GB1229396A GB1229396DA GB1229396A GB 1229396 A GB1229396 A GB 1229396A GB 1229396D A GB1229396D A GB 1229396DA GB 1229396 A GB1229396 A GB 1229396A
Authority
GB
United Kingdom
Prior art keywords
bisoxido
epoxidation
march
alkyl
prepared
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of GB1229396A publication Critical patent/GB1229396A/en
Expired legal-status Critical Current

Links

Classifications

    • EFIXED CONSTRUCTIONS
    • E04BUILDING
    • E04BGENERAL BUILDING CONSTRUCTIONS; WALLS, e.g. PARTITIONS; ROOFS; FLOORS; CEILINGS; INSULATION OR OTHER PROTECTION OF BUILDINGS
    • E04B1/00Constructions in general; Structures which are not restricted either to walls, e.g. partitions, or floors or ceilings or roofs
    • E04B1/343Structures characterised by movable, separable, or collapsible parts, e.g. for transport
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J7/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Architecture (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Electromagnetism (AREA)
  • Civil Engineering (AREA)
  • Structural Engineering (AREA)
  • Steroid Compounds (AREA)

Abstract

1,229,396. 6α,7α; 16α,17α-Bisoxido-steroids. SCHERICO Ltd. 24 March, 1969 [25 March, 1968 (2)], No. 15214/69. Heading C2U. Novel 6α,7α; 16α,17α - bisoxido - 16# - (C 1-6 - alkyl)-progesterones are prepared by epoxidation of the corresponding 6,7; 16,17-unsaturated steroids directly or via the 16α,17α-monoepoxy compounds. Epoxidation is effected with an aromatic peracid or, when the mono-epoxy compounds are required, with alkaline hydrogen peroxide. The starting materials may in turn be prepared by dehydrogenation of 16-alkyl-16- dehydropregnenolones with bromine in presence of an HBr acceptor, an inorganic bromide salt and a basic solvent. The products may be converted into 6-halo-16-alkylidene-17α-acyloxy-6- dehydroprogesterones by the method disclosed in Specification 1,229,397.
GB1229396D 1968-03-25 1969-03-24 Expired GB1229396A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US71553468A 1968-03-25 1968-03-25
US71553368A 1968-03-25 1968-03-25

Publications (1)

Publication Number Publication Date
GB1229396A true GB1229396A (en) 1971-04-21

Family

ID=27109364

Family Applications (2)

Application Number Title Priority Date Filing Date
GB1229397D Expired GB1229397A (en) 1968-03-25 1969-03-24
GB1229396D Expired GB1229396A (en) 1968-03-25 1969-03-24

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GB1229397D Expired GB1229397A (en) 1968-03-25 1969-03-24

Country Status (11)

Country Link
BE (2) BE730362A (en)
CH (2) CH510651A (en)
DE (2) DE1914826A1 (en)
DK (2) DK127293B (en)
ES (1) ES365181A1 (en)
FI (2) FI46953C (en)
FR (2) FR2016739A1 (en)
GB (2) GB1229397A (en)
IL (2) IL31883A (en)
NL (2) NL6904493A (en)
SE (1) SE362076B (en)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3462425A (en) * 1958-04-29 1969-08-19 Merck Ag E 6-halogeno-6-dehydro-3-keto-steroids
US3076823A (en) * 1961-07-03 1963-02-05 Syntex Corp Process for the production of 6-chloro-3-keto-deta steroid compounds
FR1481023A (en) * 1962-08-24 1967-05-19 Schering Ag New derivatives of delta4.6-pregnadiene-17-ol-3. 20-dione and their preparation

Also Published As

Publication number Publication date
ES365181A1 (en) 1971-06-16
NL6904493A (en) 1969-09-29
IL31882A (en) 1974-01-14
SE362076B (en) 1973-11-26
FR2070048A1 (en) 1971-09-10
NL6904492A (en) 1969-09-29
BE730362A (en) 1969-09-24
FI46950B (en) 1973-05-02
IL31882A0 (en) 1969-05-28
CH510652A (en) 1971-07-31
FI46953B (en) 1973-05-02
GB1229397A (en) 1971-04-21
CH510651A (en) 1971-07-31
FI46950C (en) 1973-08-10
DK127293B (en) 1973-10-15
BE730363A (en) 1969-09-24
FI46953C (en) 1973-08-10
DK122723B (en) 1972-04-04
IL31883A (en) 1974-01-14
DE1914826A1 (en) 1969-10-16
DE1914825A1 (en) 1969-10-09
FR2016739A1 (en) 1970-05-15
IL31883A0 (en) 1969-05-28
FR2070048B1 (en) 1973-07-13

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PLNP Patent lapsed through nonpayment of renewal fees