GB1216349A - A process for the manufacture of dispersible granulates - Google Patents

A process for the manufacture of dispersible granulates

Info

Publication number
GB1216349A
GB1216349A GB5819967A GB5819967A GB1216349A GB 1216349 A GB1216349 A GB 1216349A GB 5819967 A GB5819967 A GB 5819967A GB 5819967 A GB5819967 A GB 5819967A GB 1216349 A GB1216349 A GB 1216349A
Authority
GB
United Kingdom
Prior art keywords
polyvinyl pyrrolidone
dec
magnesium
organic solvent
sulphate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB5819967A
Inventor
Luis Picas Tort
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of GB1216349A publication Critical patent/GB1216349A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction

Abstract

1,216,349. Granulated animal feed supplements. L. P. TORT. 21 Dec., 1967 [21 Dec., 1966; 19 Dec., 1967], No. 58199/67. Headings A2B and A2E. [Also in Division A5] Granulates suitable for administration to animals in drinking liquid are made as follows: (a) reducing to a ground mixture a raw material containing at least one active therapeutic and/or nutritive ingredient normally adversely affected by the influence of light, air or atmospheric agents; (b) mixing and homogenizing the ground mixture; (c) wetting the homogenized raw material with an organic solvent containing dissolved polyvinyl pyrrolidone, n-lowryl sulphates, dioctyl sodium sulphasuccinates, alginates and/or polyethylene glycols, whereby to form a paste; (d) granulating the paste; (e) removing the solvent from the dry granules; and (f) sieving the dry granules to separate fine materials. Materials: minerals, vitamins, amino acids, antibiotics and hormones. Solvents: methanol, ethanol, isopropanol, acetone, benzene, dioctane and toluol. Granulation may be effected through a 20 mesh sieve. Final sieving is through a 16 mesh sieve. The Examples are directed to making granulates from formulations composed of: (1) specified vitamins, glucose, monosodium glutamate, sorbic acid, yellow dye, polyvinyl pyrrolidone and isopropyl alcohol; (2) specified vitamins, copper sulphate, cobalt sulphate, magnesium citrate, magnesium glycero phosphate, iron saccharate, sodium selenite, zinc chloride, glucose, glutannic acid, sorbic acid, polyvinyl pyrrolidone and isopropyl alcohol; (4) 1-(4-amino-2n-propyl-5- pyridy methyl)- 2 - pyrroline, sulphadimethylpyrimidine, Vitamin K, magnesium sulphate, dextrose, polyvinyl pyrrolidone and organic solvent; and (5) phenothiazine, piperazine citrate, magnesium sulphate, polyvinyl pyrrolidone and organic solvent.
GB5819967A 1966-12-21 1967-12-21 A process for the manufacture of dispersible granulates Expired GB1216349A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES33541566 1966-12-21
ES34907367 1967-12-19

Publications (1)

Publication Number Publication Date
GB1216349A true GB1216349A (en) 1970-12-16

Family

ID=26155719

Family Applications (1)

Application Number Title Priority Date Filing Date
GB5819967A Expired GB1216349A (en) 1966-12-21 1967-12-21 A process for the manufacture of dispersible granulates

Country Status (1)

Country Link
GB (1) GB1216349A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2611497A1 (en) * 1987-02-27 1988-09-09 Fabre Pierre Cosmetique Agglomerates, their preparation and pharmaceutical and/or cosmetic compositions containing them
EP0517423A1 (en) * 1991-06-04 1992-12-09 Kraft General Foods, Inc. Readily-dispersible, Hydrocolloid containing agglomerates and process therefor
US5384124A (en) * 1988-07-21 1995-01-24 Farmalyoc Solid porous unitary form comprising micro-particles and/or nano-particles, and its preparation

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2611497A1 (en) * 1987-02-27 1988-09-09 Fabre Pierre Cosmetique Agglomerates, their preparation and pharmaceutical and/or cosmetic compositions containing them
US5384124A (en) * 1988-07-21 1995-01-24 Farmalyoc Solid porous unitary form comprising micro-particles and/or nano-particles, and its preparation
EP0517423A1 (en) * 1991-06-04 1992-12-09 Kraft General Foods, Inc. Readily-dispersible, Hydrocolloid containing agglomerates and process therefor

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