GB1199249A - Direct Mono-Esterification of Aryl Malonic Acids - Google Patents

Direct Mono-Esterification of Aryl Malonic Acids

Info

Publication number
GB1199249A
GB1199249A GB6147168A GB6147168A GB1199249A GB 1199249 A GB1199249 A GB 1199249A GB 6147168 A GB6147168 A GB 6147168A GB 6147168 A GB6147168 A GB 6147168A GB 1199249 A GB1199249 A GB 1199249A
Authority
GB
United Kingdom
Prior art keywords
esterification
malonic acids
aryl
mono
aryl malonic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB6147168A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Charles Pfizer and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc, Charles Pfizer and Co Inc filed Critical Pfizer Inc
Publication of GB1199249A publication Critical patent/GB1199249A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/34—Esters of acyclic saturated polycarboxylic acids having an esterified carboxyl group bound to an acyclic carbon atom
    • C07C69/38—Malonic acid esters

Abstract

1,199,249. Mono-esterification of aryl malonic acids. CHAS. PFIZER & CO. Inc. 24 Dec., 1968 [20 Sept., 1968], No. 61471/68. Headings C2C and C2U. Aryl malonic acids, wherein the term "aryl" includes heterocyclic radicals, are mono-esterified by reaction with an alcohol (which may be a saturated or unsaturated aliphatic, alicyclic or heterocyclic alcohol, cholesterol, or a phenol or a naphthol) in the presence of phosphorus oxychloride or phosphorus oxybromide, preferably at 60-110‹ C. in an inert solvent. Extensive lists of examples are given.
GB6147168A 1968-09-20 1968-12-24 Direct Mono-Esterification of Aryl Malonic Acids Expired GB1199249A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US76132068A 1968-09-20 1968-09-20

Publications (1)

Publication Number Publication Date
GB1199249A true GB1199249A (en) 1970-07-15

Family

ID=25061877

Family Applications (1)

Application Number Title Priority Date Filing Date
GB6147168A Expired GB1199249A (en) 1968-09-20 1968-12-24 Direct Mono-Esterification of Aryl Malonic Acids

Country Status (4)

Country Link
JP (1) JPS5129144B1 (en)
DE (1) DE1938460A1 (en)
FR (1) FR2018474A1 (en)
GB (1) GB1199249A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2316212A1 (en) * 1975-06-20 1977-01-28 Chinoin Gyogyszer Es Vegyeszet PROCESS FOR THE PREPARATION OF NEW MALONIC ESTERS

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2316212A1 (en) * 1975-06-20 1977-01-28 Chinoin Gyogyszer Es Vegyeszet PROCESS FOR THE PREPARATION OF NEW MALONIC ESTERS

Also Published As

Publication number Publication date
FR2018474A1 (en) 1970-05-29
JPS5129144B1 (en) 1976-08-24
DE1938460A1 (en) 1970-07-02

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Legal Events

Date Code Title Description
PS Patent sealed
PE20 Patent expired after termination of 20 years