GB1183665A - A 1-Amino-Ethyldimethyl-Adamantane - Google Patents
A 1-Amino-Ethyldimethyl-AdamantaneInfo
- Publication number
- GB1183665A GB1183665A GB04629/68A GB1462968A GB1183665A GB 1183665 A GB1183665 A GB 1183665A GB 04629/68 A GB04629/68 A GB 04629/68A GB 1462968 A GB1462968 A GB 1462968A GB 1183665 A GB1183665 A GB 1183665A
- Authority
- GB
- United Kingdom
- Prior art keywords
- dimethyladamantane
- ethyl
- amino
- acid
- march
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- FVDKRDINZWLTIX-UHFFFAOYSA-N 1-(1,2-dimethyl-2-adamantyl)ethanamine Chemical compound NC(C)C1(C2(CC3CC(CC1C3)C2)C)C FVDKRDINZWLTIX-UHFFFAOYSA-N 0.000 title 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 5
- QJZCXHNEPQJAPJ-UHFFFAOYSA-N 3-ethyl-5,7-dimethyladamantan-1-amine Chemical compound C1C(C2)(C)CC3(C)CC2(N)CC1(CC)C3 QJZCXHNEPQJAPJ-UHFFFAOYSA-N 0.000 abstract 3
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 abstract 3
- FTNPDAKMYKMVKB-UHFFFAOYSA-N 1-ethyl-3,5-dimethyladamantane Chemical compound C1C(C2)CC3(C)CC2(C)CC1(CC)C3 FTNPDAKMYKMVKB-UHFFFAOYSA-N 0.000 abstract 2
- 229960000583 acetic acid Drugs 0.000 abstract 2
- YOFJQKMKOKILGY-UHFFFAOYSA-N 1-ethyl-3,5-dimethyl-7-nitroadamantane Chemical compound C1C(C2)(C)CC3(C)CC1(CC)CC2([N+]([O-])=O)C3 YOFJQKMKOKILGY-UHFFFAOYSA-N 0.000 abstract 1
- DYHYRNOUWAAUDI-UHFFFAOYSA-N 3-ethyl-5,7-dimethyladamantan-1-ol Chemical compound C1C(C2)(C)CC3(C)CC2(O)CC1(CC)C3 DYHYRNOUWAAUDI-UHFFFAOYSA-N 0.000 abstract 1
- 238000006434 Ritter amidation reaction Methods 0.000 abstract 1
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 230000000840 anti-viral effect Effects 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- KRVSOGSZCMJSLX-UHFFFAOYSA-L chromic acid Substances O[Cr](O)(=O)=O KRVSOGSZCMJSLX-UHFFFAOYSA-L 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- AWJWCTOOIBYHON-UHFFFAOYSA-N furo[3,4-b]pyrazine-5,7-dione Chemical compound C1=CN=C2C(=O)OC(=O)C2=N1 AWJWCTOOIBYHON-UHFFFAOYSA-N 0.000 abstract 1
- 239000012362 glacial acetic acid Substances 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- ATXHORWDVPVGRM-UHFFFAOYSA-N n-(3-ethyl-5,7-dimethyl-1-adamantyl)acetamide Chemical compound C1C(C2)(C)CC3(C)CC1(CC)CC2(NC(C)=O)C3 ATXHORWDVPVGRM-UHFFFAOYSA-N 0.000 abstract 1
- 238000006396 nitration reaction Methods 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000001117 sulphuric acid Substances 0.000 abstract 1
- 235000011149 sulphuric acid Nutrition 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US62694667A | 1967-03-30 | 1967-03-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1183665A true GB1183665A (en) | 1970-03-11 |
Family
ID=24512521
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB04629/68A Expired GB1183665A (en) | 1967-03-30 | 1968-03-27 | A 1-Amino-Ethyldimethyl-Adamantane |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US3450761A (enExample) |
| BE (1) | BE712870A (enExample) |
| CH (1) | CH509968A (enExample) |
| DE (1) | DE1668676A1 (enExample) |
| FR (2) | FR1584997A (enExample) |
| GB (1) | GB1183665A (enExample) |
| NL (1) | NL6803856A (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES413944A1 (es) * | 1972-04-20 | 1976-06-01 | Merz & Co | Procedimiento para la preparacion de compuestos de adamen- tano trisustituidos en las posiciones 1,3,5. |
| ATE94384T1 (de) * | 1989-04-14 | 1993-10-15 | Merz & Co Gmbh & Co | Verwendung von adamantan-derivaten zur praevention und behandlung der cerebralen ischaemie. |
| US5576355A (en) * | 1993-06-04 | 1996-11-19 | Mobil Oil Corp. | Diamondoid derivatives for pharmaceutical use |
| DE19531342B4 (de) * | 1995-08-25 | 2007-11-29 | Merz Pharma Gmbh & Co. Kgaa | Verwendung von Aminoadamantan-Verbindungen als Immunregulatoren |
| WO2005062724A2 (en) * | 2003-12-31 | 2005-07-14 | Sun Pharmaceutical Industries Limited | Novel process for the preparation of aminoadamantane derivatives |
-
1967
- 1967-03-30 US US626946A patent/US3450761A/en not_active Expired - Lifetime
-
1968
- 1968-02-27 DE DE19681668676 patent/DE1668676A1/de active Pending
- 1968-03-19 NL NL6803856A patent/NL6803856A/xx unknown
- 1968-03-27 CH CH451668A patent/CH509968A/de not_active IP Right Cessation
- 1968-03-27 GB GB04629/68A patent/GB1183665A/en not_active Expired
- 1968-03-28 FR FR1584997D patent/FR1584997A/fr not_active Expired
- 1968-03-28 BE BE712870D patent/BE712870A/xx unknown
- 1968-03-28 FR FR145788A patent/FR7597M/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| CH509968A (de) | 1971-07-15 |
| FR1584997A (enExample) | 1970-01-09 |
| BE712870A (enExample) | 1968-09-30 |
| DE1668676A1 (de) | 1971-09-16 |
| FR7597M (enExample) | 1970-01-12 |
| NL6803856A (enExample) | 1968-10-01 |
| US3450761A (en) | 1969-06-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |