GB1183641A - Salicylanilide Derivatives, their preparation and Compositions containing them - Google Patents
Salicylanilide Derivatives, their preparation and Compositions containing themInfo
- Publication number
- GB1183641A GB1183641A GB2576267A GB2576267A GB1183641A GB 1183641 A GB1183641 A GB 1183641A GB 2576267 A GB2576267 A GB 2576267A GB 2576267 A GB2576267 A GB 2576267A GB 1183641 A GB1183641 A GB 1183641A
- Authority
- GB
- United Kingdom
- Prior art keywords
- radical
- anthelmintic
- antibacterial
- compound
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000203 mixture Substances 0.000 title abstract 4
- 238000002360 preparation method Methods 0.000 title abstract 2
- WKEDVNSFRWHDNR-UHFFFAOYSA-N salicylanilide Chemical class OC1=CC=CC=C1C(=O)NC1=CC=CC=C1 WKEDVNSFRWHDNR-UHFFFAOYSA-N 0.000 title abstract 2
- GLUUGHFHXGJENI-UHFFFAOYSA-N Piperazine Chemical compound C1CNCCN1 GLUUGHFHXGJENI-UHFFFAOYSA-N 0.000 abstract 4
- 230000000507 anthelmentic effect Effects 0.000 abstract 4
- 230000000844 anti-bacterial effect Effects 0.000 abstract 4
- 125000003545 alkoxy group Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- HZAXFHJVJLSVMW-UHFFFAOYSA-N 2-Aminoethan-1-ol Chemical compound NCCO HZAXFHJVJLSVMW-UHFFFAOYSA-N 0.000 abstract 2
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 abstract 2
- BAVYZALUXZFZLV-UHFFFAOYSA-N Methylamine Chemical compound NC BAVYZALUXZFZLV-UHFFFAOYSA-N 0.000 abstract 2
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000001188 haloalkyl group Chemical group 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- -1 nitro, cyano, hydroxy, amino Chemical group 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- KKFDJZZADQONDE-UHFFFAOYSA-N (hydridonitrato)hydroxidocarbon(.) Chemical group O[C]=N KKFDJZZADQONDE-UHFFFAOYSA-N 0.000 abstract 1
- WJFKNYWRSNBZNX-UHFFFAOYSA-N 10H-phenothiazine Chemical compound C1=CC=C2NC3=CC=CC=C3SC2=C1 WJFKNYWRSNBZNX-UHFFFAOYSA-N 0.000 abstract 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract 1
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 abstract 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
- HLFSDGLLUJUHTE-SNVBAGLBSA-N Levamisole Chemical compound C1([C@H]2CN3CCSC3=N2)=CC=CC=C1 HLFSDGLLUJUHTE-SNVBAGLBSA-N 0.000 abstract 1
- 229930182555 Penicillin Natural products 0.000 abstract 1
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 abstract 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- RAHZWNYVWXNFOC-UHFFFAOYSA-N Sulphur dioxide Chemical group O=S=O RAHZWNYVWXNFOC-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000005529 alkyleneoxy group Chemical group 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 229940058905 antimony compound for treatment of leishmaniasis and trypanosomiasis Drugs 0.000 abstract 1
- 150000001463 antimony compounds Chemical class 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 239000011575 calcium Substances 0.000 abstract 1
- 229910052791 calcium Inorganic materials 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
- 239000011248 coating agent Substances 0.000 abstract 1
- 238000000576 coating method Methods 0.000 abstract 1
- 229910052802 copper Inorganic materials 0.000 abstract 1
- 239000010949 copper Substances 0.000 abstract 1
- 239000002537 cosmetic Substances 0.000 abstract 1
- 239000006071 cream Substances 0.000 abstract 1
- 239000002781 deodorant agent Substances 0.000 abstract 1
- 239000000645 desinfectant Substances 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 238000010410 dusting Methods 0.000 abstract 1
- 230000002070 germicidal effect Effects 0.000 abstract 1
- 125000004356 hydroxy functional group Chemical group O* 0.000 abstract 1
- BLNWTAHYTCHDJH-UHFFFAOYSA-O hydroxy(oxo)azanium Chemical compound O[NH+]=O BLNWTAHYTCHDJH-UHFFFAOYSA-O 0.000 abstract 1
- 229910052742 iron Inorganic materials 0.000 abstract 1
- 239000006210 lotion Substances 0.000 abstract 1
- 229910052751 metal Inorganic materials 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 150000002739 metals Chemical class 0.000 abstract 1
- 150000002903 organophosphorus compounds Chemical class 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 229940049954 penicillin Drugs 0.000 abstract 1
- 229950000688 phenothiazine Drugs 0.000 abstract 1
- 239000011591 potassium Substances 0.000 abstract 1
- 229910052700 potassium Inorganic materials 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1
- 239000011734 sodium Substances 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- 150000003456 sulfonamides Chemical class 0.000 abstract 1
- 239000004308 thiabendazole Substances 0.000 abstract 1
- WJCNZQLZVWNLKY-UHFFFAOYSA-N thiabendazole Chemical compound S1C=NC(C=2NC3=CC=CC=C3N=2)=C1 WJCNZQLZVWNLKY-UHFFFAOYSA-N 0.000 abstract 1
- 229960004546 thiabendazole Drugs 0.000 abstract 1
- 235000010296 thiabendazole Nutrition 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US55569466A | 1966-06-07 | 1966-06-07 | |
| US57347466A | 1966-08-19 | 1966-08-19 | |
| US63444267A | 1967-04-28 | 1967-04-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1183641A true GB1183641A (en) | 1970-03-11 |
Family
ID=27415707
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2576267A Expired GB1183641A (en) | 1966-06-07 | 1967-06-05 | Salicylanilide Derivatives, their preparation and Compositions containing them |
Country Status (10)
| Country | Link |
|---|---|
| BE (1) | BE699632A (enrdf_load_stackoverflow) |
| BR (1) | BR6790160D0 (enrdf_load_stackoverflow) |
| DE (1) | DE1618709B2 (enrdf_load_stackoverflow) |
| DK (1) | DK146016C (enrdf_load_stackoverflow) |
| ES (1) | ES341316A1 (enrdf_load_stackoverflow) |
| FR (1) | FR1605533A (enrdf_load_stackoverflow) |
| GB (1) | GB1183641A (enrdf_load_stackoverflow) |
| GR (1) | GR33859B (enrdf_load_stackoverflow) |
| IL (1) | IL27982A (enrdf_load_stackoverflow) |
| NL (1) | NL141088B (enrdf_load_stackoverflow) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2181790A1 (en) * | 1972-03-07 | 1973-12-07 | Janssen Pharmaceutica Nv | Salicylic acid anilides - from salicylic halides and aniline derivs, anthel-mintics, coccidiostatics |
| DE2610837A1 (de) * | 1975-03-18 | 1976-09-30 | Janssen Pharmaceutica Nv | Salicylanilid-derivate |
| EP0104677A1 (en) * | 1982-09-17 | 1984-04-04 | Janssen Pharmaceutica N.V. | Chemical sterilisation of insects with salicyl anilides |
| US4470979A (en) * | 1982-09-17 | 1984-09-11 | Janssen Pharmaceutica N.V. | Chemical sterilization of insects with salicylanilides |
| US4587361A (en) * | 1984-05-07 | 1986-05-06 | Smithkline Beckman Corporation | Anthelmintic benzamides |
| GB2247884A (en) * | 1990-09-11 | 1992-03-18 | Chanelle Chemicals Ltd | Manufacture of a salicylanilide derivative |
| WO2022076565A1 (en) | 2020-10-07 | 2022-04-14 | Sorrento Therapeutics, Inc. | Salicylanilide analogs for use in the treatment of coronavirus |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL7012496A (enrdf_load_stackoverflow) * | 1969-09-08 | 1971-03-10 |
-
1967
- 1967-05-14 IL IL2798267A patent/IL27982A/xx unknown
- 1967-05-22 GR GR670133859A patent/GR33859B/el unknown
- 1967-06-02 ES ES341316A patent/ES341316A1/es not_active Expired
- 1967-06-05 GB GB2576267A patent/GB1183641A/en not_active Expired
- 1967-06-06 NL NL6707849A patent/NL141088B/xx not_active IP Right Cessation
- 1967-06-06 BR BR19016067A patent/BR6790160D0/pt unknown
- 1967-06-06 DK DK295167A patent/DK146016C/da not_active IP Right Cessation
- 1967-06-07 BE BE699632D patent/BE699632A/xx not_active IP Right Cessation
- 1967-06-07 FR FR109487A patent/FR1605533A/fr not_active Expired
- 1967-06-07 DE DE19671618709 patent/DE1618709B2/de active Granted
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2181790A1 (en) * | 1972-03-07 | 1973-12-07 | Janssen Pharmaceutica Nv | Salicylic acid anilides - from salicylic halides and aniline derivs, anthel-mintics, coccidiostatics |
| DE2610837A1 (de) * | 1975-03-18 | 1976-09-30 | Janssen Pharmaceutica Nv | Salicylanilid-derivate |
| EP0104677A1 (en) * | 1982-09-17 | 1984-04-04 | Janssen Pharmaceutica N.V. | Chemical sterilisation of insects with salicyl anilides |
| US4470979A (en) * | 1982-09-17 | 1984-09-11 | Janssen Pharmaceutica N.V. | Chemical sterilization of insects with salicylanilides |
| US4587361A (en) * | 1984-05-07 | 1986-05-06 | Smithkline Beckman Corporation | Anthelmintic benzamides |
| GB2247884A (en) * | 1990-09-11 | 1992-03-18 | Chanelle Chemicals Ltd | Manufacture of a salicylanilide derivative |
| GB2247884B (en) * | 1990-09-11 | 1994-05-11 | Chanelle Chemicals Ltd | Manufacture of a salicylanilide derivative |
| WO2022076565A1 (en) | 2020-10-07 | 2022-04-14 | Sorrento Therapeutics, Inc. | Salicylanilide analogs for use in the treatment of coronavirus |
Also Published As
| Publication number | Publication date |
|---|---|
| BR6790160D0 (pt) | 1973-04-12 |
| DK146016B (da) | 1983-05-24 |
| NL141088B (nl) | 1974-02-15 |
| ES341316A1 (es) | 1968-09-01 |
| NL6707849A (enrdf_load_stackoverflow) | 1967-12-08 |
| FR1605533A (en) | 1979-02-23 |
| IL27982A (en) | 1971-06-23 |
| BE699632A (enrdf_load_stackoverflow) | 1967-12-07 |
| DE1618709B2 (de) | 1974-03-07 |
| DE1618709C3 (enrdf_load_stackoverflow) | 1974-10-17 |
| GR33859B (el) | 1968-02-09 |
| DE1618709A1 (de) | 1971-01-21 |
| DK146016C (da) | 1983-10-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PE20 | Patent expired after termination of 20 years |