GB1177083A - Benzoxazine Derivatives - Google Patents
Benzoxazine DerivativesInfo
- Publication number
- GB1177083A GB1177083A GB07810/66A GB1781066A GB1177083A GB 1177083 A GB1177083 A GB 1177083A GB 07810/66 A GB07810/66 A GB 07810/66A GB 1781066 A GB1781066 A GB 1781066A GB 1177083 A GB1177083 A GB 1177083A
- Authority
- GB
- United Kingdom
- Prior art keywords
- lower alkyl
- benzoxazine
- dihydro
- april
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/02—1,2-Oxazines; Hydrogenated 1,2-oxazines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1,177,083. 1-H-3,4-Dihydro-2,3-benzoxazine. GRUPPO LEPETIT S.p.A. 10 April, 1967 [22 April, 1966], No. 17810/66. Heading C2C. Novel compounds of formula wherein R is hydrogen or a lower alkyl of C 1 -C 8 , halo-lower alkyl of C 1 -C 8 , dialkylamino-(lower alkyl of C 1 -C 8 ), aryl (lower alkyl of C 1 -C 8 ) optionally substituted by lower alkoxy of C 1-8 in the aryl ring, arylcarbamylmethyl, lower alkyl of C 1 -C 8 substituted with a heterocyclic nitrogen containing ring of 5-6 atoms, hydroxy-lower alkyl of C 1 -C 8 , acyloxy-(lower alkyl of C 1 -C 8 ), carbamyl, phenylcarbamyl or guanyl group or the acyl radical of a carboxylic acid are prepared from α.α<SP>1</SP>-dibromo-o-xylene and N-hydroxyurethan in the presence of an alkali metal hydroxide and splitting off the carboethoxy group from the intermediate N-carboethoxy-1H-3,4-dihydro-2,3-benzoxazine by hydrolytic cleavage, and the N-unsubstituted 1H-3,4-dihydro-2,3- benzoxazine so obtained is then optionally treated with an agent capable of introducing the radical R above, when R is other than hydrogen. Pharmaceutical compositions having sedative, tranquillizing and anti-inflammatory activity comprise an above novel compound and a carrier therefor.
Priority Applications (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB07810/66A GB1177083A (en) | 1966-04-22 | 1966-04-22 | Benzoxazine Derivatives |
IL2775867A IL27758A (en) | 1966-04-22 | 1967-04-07 | 1h-3,4-dihydro-2,3-benzoxazine derivatives and process for their preparation |
NL6705062A NL150448B (en) | 1966-04-22 | 1967-04-10 | PROCEDURE FOR PREPARING 2,3-BENZOXAZINE DERIVATIVES. |
ES339602A ES339602A1 (en) | 1966-04-22 | 1967-04-21 | Benzoxazine Derivatives |
BE697370D BE697370A (en) | 1966-04-22 | 1967-04-21 | |
CH573067A CH482703A (en) | 1966-04-22 | 1967-04-21 | Process for preparing a benzoxazine having pharmacological activity |
FR103699A FR1524463A (en) | 1966-04-22 | 1967-04-21 | 1 h-3, 4-dihydro-2, 3-benzoxazine derivatives and processes for their preparation |
DE19671695363 DE1695363C3 (en) | 1966-04-22 | 1967-04-21 | 1H-3.4 dihydro-2,3 benzoxazine and its substituted derivatives and processes for the preparation of these compounds |
FR114289A FR6523M (en) | 1966-04-22 | 1967-07-13 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB07810/66A GB1177083A (en) | 1966-04-22 | 1966-04-22 | Benzoxazine Derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1177083A true GB1177083A (en) | 1970-01-07 |
Family
ID=10101633
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB07810/66A Expired GB1177083A (en) | 1966-04-22 | 1966-04-22 | Benzoxazine Derivatives |
Country Status (8)
Country | Link |
---|---|
BE (1) | BE697370A (en) |
CH (1) | CH482703A (en) |
DE (1) | DE1695363C3 (en) |
ES (1) | ES339602A1 (en) |
FR (1) | FR6523M (en) |
GB (1) | GB1177083A (en) |
IL (1) | IL27758A (en) |
NL (1) | NL150448B (en) |
-
1966
- 1966-04-22 GB GB07810/66A patent/GB1177083A/en not_active Expired
-
1967
- 1967-04-07 IL IL2775867A patent/IL27758A/en unknown
- 1967-04-10 NL NL6705062A patent/NL150448B/en unknown
- 1967-04-21 DE DE19671695363 patent/DE1695363C3/en not_active Expired
- 1967-04-21 CH CH573067A patent/CH482703A/en not_active IP Right Cessation
- 1967-04-21 ES ES339602A patent/ES339602A1/en not_active Expired
- 1967-04-21 BE BE697370D patent/BE697370A/xx unknown
- 1967-07-13 FR FR114289A patent/FR6523M/fr not_active Expired
Also Published As
Publication number | Publication date |
---|---|
IL27758A (en) | 1971-07-28 |
FR6523M (en) | 1968-12-09 |
DE1695363A1 (en) | 1972-01-13 |
DE1695363C3 (en) | 1975-06-12 |
NL150448B (en) | 1976-08-16 |
DE1695363B2 (en) | 1974-10-17 |
NL6705062A (en) | 1967-10-23 |
ES339602A1 (en) | 1968-07-16 |
CH482703A (en) | 1969-12-15 |
BE697370A (en) | 1967-10-02 |
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