GB1175622A - Improvements in or relating to Collagen Films and Filaments and the Manufacture thereof - Google Patents

Improvements in or relating to Collagen Films and Filaments and the Manufacture thereof

Info

Publication number
GB1175622A
GB1175622A GB00556/67A GB1055667A GB1175622A GB 1175622 A GB1175622 A GB 1175622A GB 00556/67 A GB00556/67 A GB 00556/67A GB 1055667 A GB1055667 A GB 1055667A GB 1175622 A GB1175622 A GB 1175622A
Authority
GB
United Kingdom
Prior art keywords
collagen
suspension
acid
soluble
aqueous solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB00556/67A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
USM Corp
Original Assignee
USM Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by USM Corp filed Critical USM Corp
Publication of GB1175622A publication Critical patent/GB1175622A/en
Expired legal-status Critical Current

Links

Classifications

    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01F—CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
    • D01F4/00—Monocomponent artificial filaments or the like of proteins; Manufacture thereof
    • A—HUMAN NECESSITIES
    • A22—BUTCHERING; MEAT TREATMENT; PROCESSING POULTRY OR FISH
    • A22C—PROCESSING MEAT, POULTRY, OR FISH
    • A22C13/00—Sausage casings
    • A22C13/0013—Chemical composition of synthetic sausage casings
    • A—HUMAN NECESSITIES
    • A22—BUTCHERING; MEAT TREATMENT; PROCESSING POULTRY OR FISH
    • A22C—PROCESSING MEAT, POULTRY, OR FISH
    • A22C13/00—Sausage casings
    • A22C13/0013—Chemical composition of synthetic sausage casings
    • A22C13/0016—Chemical composition of synthetic sausage casings based on proteins, e.g. collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
    • A61L17/06—At least partially resorbable materials
    • A61L17/08—At least partially resorbable materials of animal origin, e.g. catgut, collagen
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C48/00—Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor
    • B29C48/03—Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor characterised by the shape of the extruded material at extrusion
    • B29C48/09—Articles with cross-sections having partially or fully enclosed cavities, e.g. pipes or channels
    • B29C48/10—Articles with cross-sections having partially or fully enclosed cavities, e.g. pipes or channels flexible, e.g. blown foils
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C48/00—Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor
    • B29C48/25—Component parts, details or accessories; Auxiliary operations
    • B29C48/88—Thermal treatment of the stream of extruded material, e.g. cooling
    • B29C48/919—Thermal treatment of the stream of extruded material, e.g. cooling using a bath, e.g. extruding into an open bath to coagulate or cool the material
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C48/00—Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor
    • B29C48/03—Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor characterised by the shape of the extruded material at extrusion
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C48/00—Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor
    • B29C48/03—Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor characterised by the shape of the extruded material at extrusion
    • B29C48/05—Filamentary, e.g. strands

Landscapes

  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Food Science & Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Mechanical Engineering (AREA)
  • Vascular Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Materials Engineering (AREA)
  • Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Thermal Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Textile Engineering (AREA)
  • Artificial Filaments (AREA)
  • Materials For Medical Uses (AREA)
  • Peptides Or Proteins (AREA)

Abstract

1,175,622. Making collagen films and filaments. USM CORP. 7 March, 1967 [8 March, 1966], No. 10556/67. Heading B5B. Collagen filaments and films are made by treating skin material with a swelling agent and mechanically separating the swollen skin material in the presence of an aqueous medium to form a suspension of fine collagen fibres having a pH on the acid side of the isoelectric range, adding to the suspension acid-soluble collagen to provide at least 2% by weight, preferably 5 to 50% by weight, of dissolved acidsoluble collagen (based on the dry weight of collagen fibres and dissolved collagen) in the resulting suspension, if necessary adjusting the pH of the suspension so that it remains outside the isoelectric range, and extruding the suspension and coagulating the suspension using a liquid deswelling agent whereby to provide a filament or film of uniform cross-section. The suspension may have a collagen fibre contact of 3 to 6% by weight and a pH of from 3 to 3À6. The deswelling agent may be a mildly alkaline aqueous solution of a salt. The deswelling agent may be a concentrated aqueous solution of a salt soluble in water to such an extent that a saturated solution of the salt in water at ambient temperature has a concentration greater than 25%. The skin material may be limed steer hide and the swelling agent may be lactic acid. The liquid deswelling agent or coagulating bath may be a saturated aqueous solution of ammonium sulphate rendered mildly alkaline with ammonium hydroxide. The aqueous suspension containing the acid-soluble collagen is adjusted to have a pH range outside the isoelectric range of collagen but not so high or low as to cause rapid destruction of the collagen material, i.e. the pH should be above about 2À5 and below about 12. The liquid deswelling agent may be a water-soluble ketone or a concentrated, preferably at least half saturated, aqueous solution of a salt which is soluble in water, such as sodium acetate or ammonium chloride. The preferred deswelling agent is an aqueous concentrated ammonium sulphate solution. In an example, fresh steer hide is lined, unhaired, the grain surface removed in a splitting machine and the flesh side splits neutralized with acetic acid and washed with water. The splits are treated with a dilute aqueous solution of lactic acid, chopped, ground and homogenized at a pressure of 1500 to 3500 p.s.i. to form a homogenized material having a solids content of 9À5% and a pH of 3À4. Acid-soluble collagen is prepared from calfskin scrap by treating it with dilute aqueous acetic acid, the treated material is filtered, the dissolved collagen is precipitated by addition of sodium chloride to a concentration of sodium 10%, the precipitate is filtered off, redissolved in dilute acetic acid, and the salt removed by dialysis to provide a solution containing about 0À71% of soluble collagen. A mixture of 200 parts by weight of the 9À5% solids stock, 83 parts of the acid-soluble collagen solution, and lactic acid to a pH of 3À3 are mixed and extruded into a saturated aqueous solution of ammonium sulphate adjusted to pH 8À4 with ammonium hydroxide to form a collagen filament.
GB00556/67A 1966-03-08 1967-03-07 Improvements in or relating to Collagen Films and Filaments and the Manufacture thereof Expired GB1175622A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US53257066A 1966-03-08 1966-03-08

Publications (1)

Publication Number Publication Date
GB1175622A true GB1175622A (en) 1969-12-23

Family

ID=24122320

Family Applications (1)

Application Number Title Priority Date Filing Date
GB00556/67A Expired GB1175622A (en) 1966-03-08 1967-03-07 Improvements in or relating to Collagen Films and Filaments and the Manufacture thereof

Country Status (6)

Country Link
US (1) US3433864A (en)
DE (1) DE1720192C3 (en)
FR (1) FR1515365A (en)
GB (1) GB1175622A (en)
NL (1) NL6703536A (en)
SE (1) SE338490B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113046917A (en) * 2021-02-07 2021-06-29 西华师范大学 Electrostatic spinning collagen membrane and preparation method thereof

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3620775A (en) * 1968-08-12 1971-11-16 Tee Pak Inc Edible collagen casing
US3932677A (en) * 1974-10-22 1976-01-13 Tee-Pak, Inc. Collagen casings from limed hide collagen
CA1073360A (en) * 1975-10-22 1980-03-11 John R. Daniels Non-antigenic collagen and articles of manufacture
US4544516A (en) * 1982-07-28 1985-10-01 Battelle Development Corporation Collagen orientation
WO1995025550A1 (en) * 1994-03-22 1995-09-28 Organogenesis Inc. Biocompatible prosthetic devices

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2934446A (en) * 1955-12-21 1960-04-26 United Shoe Machinery Corp Collagen fiber masses and methods of making the same
US2934447A (en) * 1957-10-22 1960-04-26 United Shoe Machinery Corp Collagen fiber masses and methods of making the same
US3071483A (en) * 1960-05-03 1963-01-01 United Shoe Machinery Corp Manufacture of collagen products
NL269228A (en) * 1960-09-19
US3131130A (en) * 1961-07-31 1964-04-28 Ethicon Inc Method of producing soluble collagen
US3294579A (en) * 1963-05-09 1966-12-27 United Shoe Machinery Corp Leather-like material and method of making the same
US3269851A (en) * 1963-11-29 1966-08-30 United Shoe Machinery Corp Gelatin-bonded open-fibered collagenous masses and methods of making
US3297459A (en) * 1965-04-08 1967-01-10 Armour & Co Process of preparing formed collagen bodies

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113046917A (en) * 2021-02-07 2021-06-29 西华师范大学 Electrostatic spinning collagen membrane and preparation method thereof
CN113046917B (en) * 2021-02-07 2022-10-21 西华师范大学 Electrostatic spinning collagen membrane and preparation method thereof

Also Published As

Publication number Publication date
DE1720192B2 (en) 1974-07-11
US3433864A (en) 1969-03-18
DE1720192C3 (en) 1975-03-27
DE1720192A1 (en) 1971-06-03
NL6703536A (en) 1967-09-11
SE338490B (en) 1971-09-06
FR1515365A (en) 1968-03-01

Similar Documents

Publication Publication Date Title
US4295894A (en) Method of preparing soluble collagen fibers
US3637642A (en) Process for dissolving insoluble collagen employing a mixture of an alkali metal hydroxide an alkali metal sulfate and an amine
US2445028A (en) Method of dispersing keratin proteins with amides and the composition resulting therefrom
US4268131A (en) Fiber collagen contact lens
US3123481A (en) Tanned edible collagen casing and method of producing same
US2934447A (en) Collagen fiber masses and methods of making the same
GB1175622A (en) Improvements in or relating to Collagen Films and Filaments and the Manufacture thereof
EP0083126B1 (en) A process of preparing shaped products starting from dispersions containing a coagulable amphoteric high molecular substance
GB1210859A (en) Phosphate-glutaraldehyde tanning of edible collagen casing
GB1122505A (en) Dialdehyde tanned edible collagen casing
US3505084A (en) Method of preparing a collagen sausage casing
US3894132A (en) Method of forming collagen dispersions
US4196223A (en) Method of preparing sausage casings from pig skins
US2979438A (en) Extraction of collagen
US3374103A (en) Collagen fibril and neutral salt composition
US3922356A (en) Sulfite catalyzed aluminum tannage of collagen casing
GB1494419A (en) Collagen casing slurries from limed hide collagen
GB1139233A (en) Preparation of edible collagen sausage casing
US2460809A (en) Method of preparing gelatin
IT1043758B (en) PROCEDURE FOR THE MANUFACTURE OF ARTIFICIAL TUBULAR PEELS FOR SAUSED MEAT
US3885054A (en) Edible collagen casing cross-linked by bisulfite addition
DE2310628B2 (en) Process for obtaining the corium from cattle hides
GB1239861A (en) Improvements in or relating to the production of collagen and/or gelatine
GB548248A (en) Improvements in or relating to the manufacture of transparent papers and artificial fibres
GB927282A (en) Improvements in or relating to material comprising collagen fibres

Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PLNP Patent lapsed through nonpayment of renewal fees