GB1175183A - Water Soluble Derivatives of Tetracycline Antibiotics. - Google Patents
Water Soluble Derivatives of Tetracycline Antibiotics.Info
- Publication number
- GB1175183A GB1175183A GB5428/66A GB542866A GB1175183A GB 1175183 A GB1175183 A GB 1175183A GB 5428/66 A GB5428/66 A GB 5428/66A GB 542866 A GB542866 A GB 542866A GB 1175183 A GB1175183 A GB 1175183A
- Authority
- GB
- United Kingdom
- Prior art keywords
- tetracycline
- tetracyclines
- alkaline earth
- alkali metal
- tetracycline antibiotic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229940072172 tetracycline antibiotic Drugs 0.000 title abstract 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 title 1
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 6
- 239000004098 Tetracycline Substances 0.000 abstract 5
- 235000019364 tetracycline Nutrition 0.000 abstract 4
- ZWEHNKRNPOVVGH-UHFFFAOYSA-N 2-Butanone Chemical compound CCC(C)=O ZWEHNKRNPOVVGH-UHFFFAOYSA-N 0.000 abstract 3
- ZMANZCXQSJIPKH-UHFFFAOYSA-N Triethylamine Chemical compound CCN(CC)CC ZMANZCXQSJIPKH-UHFFFAOYSA-N 0.000 abstract 3
- 229910052783 alkali metal Inorganic materials 0.000 abstract 3
- 150000001340 alkali metals Chemical class 0.000 abstract 3
- 229910052784 alkaline earth metal Inorganic materials 0.000 abstract 3
- 235000019161 pantothenic acid Nutrition 0.000 abstract 3
- 229940040944 tetracyclines Drugs 0.000 abstract 3
- 150000003522 tetracyclines Chemical class 0.000 abstract 3
- GHOKWGTUZJEAQD-ZETCQYMHSA-N (D)-(+)-Pantothenic acid Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-ZETCQYMHSA-N 0.000 abstract 2
- WQDUMFSSJAZKTM-UHFFFAOYSA-N Sodium methoxide Chemical compound [Na+].[O-]C WQDUMFSSJAZKTM-UHFFFAOYSA-N 0.000 abstract 2
- -1 alkaline earth metal salt Chemical class 0.000 abstract 2
- 150000001342 alkaline earth metals Chemical class 0.000 abstract 2
- 239000007864 aqueous solution Substances 0.000 abstract 2
- 239000002585 base Substances 0.000 abstract 2
- 229960002180 tetracycline Drugs 0.000 abstract 2
- 229930101283 tetracycline Natural products 0.000 abstract 2
- LJVDOBHBFMLPMI-XRNKAMNCSA-N (4s,4as,5as,6s,12ar)-7-bromo-4-(dimethylamino)-1,6,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide Chemical compound C1=CC(Br)=C2[C@](O)(C)[C@H]3C[C@H]4[C@H](N(C)C)C(=O)C(C(N)=O)=C(O)[C@@]4(O)C(=O)C3=C(O)C2=C1O LJVDOBHBFMLPMI-XRNKAMNCSA-N 0.000 abstract 1
- GHOKWGTUZJEAQD-UHFFFAOYSA-N Chick antidermatitis factor Natural products OCC(C)(C)C(O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-UHFFFAOYSA-N 0.000 abstract 1
- 239000004099 Chlortetracycline Substances 0.000 abstract 1
- 239000004100 Oxytetracycline Substances 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- CYDMQBQPVICBEU-UHFFFAOYSA-N chlorotetracycline Natural products C1=CC(Cl)=C2C(O)(C)C3CC4C(N(C)C)C(O)=C(C(N)=O)C(=O)C4(O)C(O)=C3C(=O)C2=C1O CYDMQBQPVICBEU-UHFFFAOYSA-N 0.000 abstract 1
- 229960004475 chlortetracycline Drugs 0.000 abstract 1
- CYDMQBQPVICBEU-XRNKAMNCSA-N chlortetracycline Chemical compound C1=CC(Cl)=C2[C@](O)(C)[C@H]3C[C@H]4[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]4(O)C(O)=C3C(=O)C2=C1O CYDMQBQPVICBEU-XRNKAMNCSA-N 0.000 abstract 1
- 235000019365 chlortetracycline Nutrition 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 229960000625 oxytetracycline Drugs 0.000 abstract 1
- IWVCMVBTMGNXQD-PXOLEDIWSA-N oxytetracycline Chemical compound C1=CC=C2[C@](O)(C)[C@H]3[C@H](O)[C@H]4[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]4(O)C(O)=C3C(=O)C2=C1O IWVCMVBTMGNXQD-PXOLEDIWSA-N 0.000 abstract 1
- 235000019366 oxytetracycline Nutrition 0.000 abstract 1
- 229940055726 pantothenic acid Drugs 0.000 abstract 1
- 239000011713 pantothenic acid Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- IWVCMVBTMGNXQD-UHFFFAOYSA-N terramycin dehydrate Natural products C1=CC=C2C(O)(C)C3C(O)C4C(N(C)C)C(O)=C(C(N)=O)C(=O)C4(O)C(O)=C3C(=O)C2=C1O IWVCMVBTMGNXQD-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/65—Tetracyclines
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB5428/66A GB1175183A (en) | 1966-02-08 | 1966-02-08 | Water Soluble Derivatives of Tetracycline Antibiotics. |
| NL6701003A NL6701003A (xx) | 1966-02-08 | 1967-01-23 | |
| GR670133434A GR33434B (el) | 1966-02-08 | 1967-02-01 | Μεθοδος δια την παρασκευην παραγωγων τετρακυκλινης. |
| BE693613D BE693613A (xx) | 1966-02-08 | 1967-02-03 | |
| DE19671618757 DE1618757A1 (de) | 1966-02-08 | 1967-02-04 | Verfahren zum Herstellen von Tetracyclinderivaten |
| CH177667A CH483399A (de) | 1966-02-08 | 1967-02-07 | Verfahren zur Herstellung von wasserlöslichen Salzen der Tetracyclniantibiotika |
| AT117067A AT270065B (de) | 1966-02-08 | 1967-02-07 | Verfahren zum Herstellen neuer, wasserlöslicher Derivate der Tetracyclinantibiotika |
| FR94155A FR1532305A (fr) | 1966-02-08 | 1967-02-08 | Nouveaux dérivés des tétracyclines et procédé pour leur préparation |
| SE175067A SE328567B (xx) | 1966-02-08 | 1967-02-08 | |
| FR105584A FR6619M (xx) | 1966-02-08 | 1967-05-08 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB5428/66A GB1175183A (en) | 1966-02-08 | 1966-02-08 | Water Soluble Derivatives of Tetracycline Antibiotics. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1175183A true GB1175183A (en) | 1969-12-23 |
Family
ID=9796007
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5428/66A Expired GB1175183A (en) | 1966-02-08 | 1966-02-08 | Water Soluble Derivatives of Tetracycline Antibiotics. |
Country Status (9)
| Country | Link |
|---|---|
| AT (1) | AT270065B (xx) |
| BE (1) | BE693613A (xx) |
| CH (1) | CH483399A (xx) |
| DE (1) | DE1618757A1 (xx) |
| FR (1) | FR6619M (xx) |
| GB (1) | GB1175183A (xx) |
| GR (1) | GR33434B (xx) |
| NL (1) | NL6701003A (xx) |
| SE (1) | SE328567B (xx) |
-
1966
- 1966-02-08 GB GB5428/66A patent/GB1175183A/en not_active Expired
-
1967
- 1967-01-23 NL NL6701003A patent/NL6701003A/xx unknown
- 1967-02-01 GR GR670133434A patent/GR33434B/el unknown
- 1967-02-03 BE BE693613D patent/BE693613A/xx unknown
- 1967-02-04 DE DE19671618757 patent/DE1618757A1/de active Pending
- 1967-02-07 CH CH177667A patent/CH483399A/de not_active IP Right Cessation
- 1967-02-07 AT AT117067A patent/AT270065B/de active
- 1967-02-08 SE SE175067A patent/SE328567B/xx unknown
- 1967-05-08 FR FR105584A patent/FR6619M/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FR6619M (xx) | 1969-01-13 |
| BE693613A (xx) | 1967-07-17 |
| CH483399A (de) | 1969-12-31 |
| AT270065B (de) | 1969-04-10 |
| SE328567B (xx) | 1970-09-21 |
| GR33434B (el) | 1967-12-02 |
| NL6701003A (xx) | 1967-08-09 |
| DE1618757A1 (de) | 1971-07-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |