GB1171476A - Phenalkylamine Compounds, Compositions containing the same and Process for Preparing the Compounds - Google Patents
Phenalkylamine Compounds, Compositions containing the same and Process for Preparing the CompoundsInfo
- Publication number
- GB1171476A GB1171476A GB4941466A GB4941466A GB1171476A GB 1171476 A GB1171476 A GB 1171476A GB 4941466 A GB4941466 A GB 4941466A GB 4941466 A GB4941466 A GB 4941466A GB 1171476 A GB1171476 A GB 1171476A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- carbon atoms
- radical
- compounds
- cycloalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
- C07C311/29—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/21—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
- C07C311/23—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atoms of the sulfonamide groups bound to acyclic carbon atoms
- C07C311/24—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atoms of the sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1,171,476. Medicines comprising sulphonamides. MEAD JOHNSON & CO. 3 Nov., 1966 [15 Nov., 1965], No. 49414/66. Heading A5B. [Also in Division C2] Pharmaceutical compositions suitable for oral, parenteral, rectal or topical administration comprise a sulphonamide of formula: wherein AlK is C 2-5 alkylene joining the benzene ring to the nitrogen atom through two or three carbon atoms; R<SP>1</SP> is an alkyl, alkenyl, cycloalkyl, or cycloalkenyl radical of up to six carbon atoms or a phenyl or naphthyl radical (optionally substituted by halogen or an alkyl alkenyl, cycloalkyl, cycloalkenyl or alkoxy radical having up to six carbon atoms); R<SP>2</SP> is hydrogen, C 1-4 alkyl, or benzyl; R<SP>3</SP> is hydrogen or an alkyl, alkenyl, cycloalkyl, cycloalkenyl, cycloalkylalkyl, cycloalkenylalkyl, polycycloalkyl, polycycloalkenyl, polycycloalkylalkyl, polycycloalkenylalkyl, aryl aralkyl, aralkenyl, aryloxyalkyl, heterocyclic, heterocycloalkyl, heteropolycyclic or heteropolycycloalkyl radical of up to 10 carbon atoms and optionally substituted by up to two substituents selected from hydroxyl, carboxyl, amino, halogen, methylenedioxy, R<SP>1</SP>SO 2 NH (where R<SP>1</SP> is as above) and C 1-4 alkyl and alkoxy; or NR<SP>2</SP>R<SP>3</SP> is a heterocyclic group having up to 11 carbon atoms; or an acid addition salt thereof (e.g. hydrochloride), together with a suitable carrier. These compounds have pressor or depressor activity. The compositions may additionally include tranquilizers, sedatives, analeptics, analgesics, antipyretics, hypnotics, antibiotics (polymixin, tyrothrycin, gramicidin, tyrocidin, neomycin), antihistamines (chlorprophenpyridamine maleate, methdilazine hydrochloride), antiinflammatory agents (cortisone phosphate), surfactants, antiseptics (thimerasol, benzalkonium chloride), or mucolytic agents (tyloxypal).
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB5371068A GB1171477A (en) | 1965-11-15 | 1966-11-03 | Novel Formylsulfonanilide Compounds and Process for making same |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US50766465A | 1965-11-15 | 1965-11-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1171476A true GB1171476A (en) | 1969-11-19 |
Family
ID=24019623
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB4941466A Expired GB1171476A (en) | 1965-11-15 | 1966-11-03 | Phenalkylamine Compounds, Compositions containing the same and Process for Preparing the Compounds |
Country Status (7)
Country | Link |
---|---|
BE (1) | BE689675A (en) |
BR (1) | BR6684565D0 (en) |
DE (1) | DE1543783A1 (en) |
FR (1) | FR5963M (en) |
GB (1) | GB1171476A (en) |
NL (1) | NL6615663A (en) |
SE (1) | SE354656B (en) |
-
1966
- 1966-11-03 GB GB4941466A patent/GB1171476A/en not_active Expired
- 1966-11-07 NL NL6615663A patent/NL6615663A/xx unknown
- 1966-11-14 BE BE689675D patent/BE689675A/xx unknown
- 1966-11-14 BR BR18456566A patent/BR6684565D0/en unknown
- 1966-11-14 SE SE1552266A patent/SE354656B/xx unknown
- 1966-11-14 FR FR83426A patent/FR5963M/fr not_active Expired
- 1966-11-15 DE DE19661543783 patent/DE1543783A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
DE1543783A1 (en) | 1970-02-26 |
NL6615663A (en) | 1967-05-16 |
SE354656B (en) | 1973-03-19 |
FR5963M (en) | 1968-04-16 |
BE689675A (en) | 1967-05-16 |
BR6684565D0 (en) | 1973-12-04 |
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