GB1169436A - Improvements in or relating to a Method of Preparing Surgical Prosthetic Implant Material for the Repair and Replacement of Vascular Organs and Tissues in Human Bodies. - Google Patents

Improvements in or relating to a Method of Preparing Surgical Prosthetic Implant Material for the Repair and Replacement of Vascular Organs and Tissues in Human Bodies.

Info

Publication number
GB1169436A
GB1169436A GB29316/67A GB2931667A GB1169436A GB 1169436 A GB1169436 A GB 1169436A GB 29316/67 A GB29316/67 A GB 29316/67A GB 2931667 A GB2931667 A GB 2931667A GB 1169436 A GB1169436 A GB 1169436A
Authority
GB
United Kingdom
Prior art keywords
collagen
product
mixture
freeze dried
glycol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB29316/67A
Inventor
Karel Kliment
Milos Stol
Milos Chvapil
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Czech Academy of Sciences CAS
Original Assignee
Czech Academy of Sciences CAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Czech Academy of Sciences CAS filed Critical Czech Academy of Sciences CAS
Publication of GB1169436A publication Critical patent/GB1169436A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/16—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/26—Mixtures of macromolecular compounds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10—Esters
    • C08F220/20—Esters of polyhydric alcohols or phenols, e.g. 2-hydroxyethyl (meth)acrylate or glycerol mono-(meth)acrylate
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F289/00—Macromolecular compounds obtained by polymerising monomers on to macromolecular compounds not provided for in groups C08F251/00 - C08F287/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Materials For Medical Uses (AREA)

Abstract

1,169,436. Porous glycol methacrylate polymer/collagen compositions. CESKOSLOVENSKA AKADEMIE VED. 26 June, 1967 [9 July, 1966], No. 29316/67. Headings C3C and C3P. A mixture of glycol monomethacrylate or polyglycol monomethacrylate having not more than 2% by wt. of a cross-linking agent and an additive capable of creating open pores of diameter at least 100 Á is polymerized, the pores are at least partially filled, during or after polymerization, with collagen and the product is maintained at a temperature not higher than 37‹ C. and is used for surgical prosthetic implants. In examples (1) glycol monomethacrylate was polymerized in the presence of an aq. glycerol mixture of collagen with glycol bismethacrylate as cross-linking agent and the water as pore former, antibiotics, trimethylol melamine as hardener for the collagen and diisopropyl percarbonate and the product was partially freeze dried; and (3) an aq. mixture of collagen and trimethylol melamine was freeze dried and covered with a mixture of dimethyl-aminoethyl acetate, aq. ammonium persulphate and both the methacrylates of (1), and the product was freeze dried. The product may be sterilized by irradiation with Co<SP>60</SP> cobalt isotope or with ethylene dioxide.
GB29316/67A 1966-07-09 1967-06-26 Improvements in or relating to a Method of Preparing Surgical Prosthetic Implant Material for the Repair and Replacement of Vascular Organs and Tissues in Human Bodies. Expired GB1169436A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CS465966 1966-07-09

Publications (1)

Publication Number Publication Date
GB1169436A true GB1169436A (en) 1969-11-05

Family

ID=5389850

Family Applications (1)

Application Number Title Priority Date Filing Date
GB29316/67A Expired GB1169436A (en) 1966-07-09 1967-06-26 Improvements in or relating to a Method of Preparing Surgical Prosthetic Implant Material for the Repair and Replacement of Vascular Organs and Tissues in Human Bodies.

Country Status (4)

Country Link
DD (1) DD62140A3 (en)
DE (1) DE1720073A1 (en)
FR (1) FR1555536A (en)
GB (1) GB1169436A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2185408A (en) * 1986-01-16 1987-07-22 Rhode Island Hospital Neovascularization

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CS216992B1 (en) * 1980-07-21 1982-12-31 Miroslav Stol Composite polymere material for the biological and medicinal utilitation and method of preparation thereof
US4452925A (en) * 1981-02-09 1984-06-05 National Patent Development Corporation Biologically stabilized compositions comprising collagen as the minor component with ethylenically unsaturated compounds used as contact lenses
US4388428A (en) * 1981-07-20 1983-06-14 National Patent Development Corporation Biologically stabilized compositions comprising collagen as the major component with ethylenically unsaturated compounds used as contact lenses
DE3825827A1 (en) * 1988-07-29 1990-02-01 Med Xeno Hairimplant Gmbh Ges Implantable artificial hair

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2185408A (en) * 1986-01-16 1987-07-22 Rhode Island Hospital Neovascularization
GB2185408B (en) * 1986-01-16 1990-02-14 Rhode Island Hospital Neovascularization

Also Published As

Publication number Publication date
FR1555536A (en) 1969-01-31
DE1720073A1 (en) 1971-06-24
DD62140A3 (en) 1968-06-05

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