GB1149066A - Penicillin esters of chloramphenicol - Google Patents

Penicillin esters of chloramphenicol

Info

Publication number
GB1149066A
GB1149066A GB34887/66A GB3488766A GB1149066A GB 1149066 A GB1149066 A GB 1149066A GB 34887/66 A GB34887/66 A GB 34887/66A GB 3488766 A GB3488766 A GB 3488766A GB 1149066 A GB1149066 A GB 1149066A
Authority
GB
United Kingdom
Prior art keywords
penicillin
chloramphenicol
carboxylic acid
imide
aug
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB34887/66A
Inventor
Conrado Folch Vazquez
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from ES0316072A external-priority patent/ES316072A1/en
Priority claimed from ES0317293A external-priority patent/ES317293A1/en
Application filed by Individual filed Critical Individual
Publication of GB1149066A publication Critical patent/GB1149066A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

1,149,066. Penicillin; chloramphenicol. C. F. VASQUEZ. 3 Aug., 1966 [3 Aug., 1965; 9 Sept., 1965; 2 July, 1966; 5 July, 1966], No. 34887/66. Headings C2A and C2C. The invention comprises penicillin esters of chloramphenicol of formula in which RCO is the acyl group of a penicillin, e.g. phenoxymethyl or phenoxyethyl penicillin. The ester is produced by reacting chloramphenicol with (a) the appropriate penicillin 3-carboxylic acid anhydride, or (b) the appropriate penicillin 3-carboxylic acid in the presence of dicyclohexylcarbo di-imide or di-isopropyl carbodi-imide, in an inert solvent. The penicillin 3-carboxylic acid anhydride may be a mixed anhydride and may be formed in situ.
GB34887/66A 1965-08-03 1966-08-03 Penicillin esters of chloramphenicol Expired GB1149066A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
ES0316072A ES316072A1 (en) 1965-08-03 1965-08-03 Procedure for preparation of chloranphenicol esters. (Machine-translation by Google Translate, not legally binding)
ES0317293A ES317293A1 (en) 1965-09-09 1965-09-09 Procedure for preparation of chloramphenicol esters. (Machine-translation by Google Translate, not legally binding)
ES32862666 1966-07-02
ES32867166 1966-07-05

Publications (1)

Publication Number Publication Date
GB1149066A true GB1149066A (en) 1969-04-16

Family

ID=27443966

Family Applications (1)

Application Number Title Priority Date Filing Date
GB34887/66A Expired GB1149066A (en) 1965-08-03 1966-08-03 Penicillin esters of chloramphenicol

Country Status (4)

Country Link
DE (1) DE1670723A1 (en)
FR (1) FR6249M (en)
GB (1) GB1149066A (en)
NL (1) NL6610897A (en)

Also Published As

Publication number Publication date
FR6249M (en) 1968-08-19
NL6610897A (en) 1967-02-06
DE1670723A1 (en) 1972-03-02

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