GB1147798A - Steroid 3-thioketals - Google Patents

Steroid 3-thioketals

Info

Publication number
GB1147798A
GB1147798A GB38295/66A GB2631866A GB1147798A GB 1147798 A GB1147798 A GB 1147798A GB 38295/66 A GB38295/66 A GB 38295/66A GB 2631866 A GB2631866 A GB 2631866A GB 1147798 A GB1147798 A GB 1147798A
Authority
GB
United Kingdom
Prior art keywords
thioketals
steroid
prepared
thioketalization
ols
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB38295/66A
Inventor
Herchel Smith
Gordon Alan Hughes
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to GB38295/66A priority Critical patent/GB1147798A/en
Priority to SE13130/66A priority patent/SE325568B/xx
Priority to ES0331807A priority patent/ES331807A1/en
Priority to DK510666AA priority patent/DK114343B/en
Priority to NL666614507A priority patent/NL153881B/en
Priority to DE19661593448 priority patent/DE1593448B1/en
Priority to CH1521166A priority patent/CH473112A/en
Priority to YU2101/66A priority patent/YU32919B/en
Priority to BR184711/66A priority patent/BR6684711D0/en
Priority to FR88010A priority patent/FR1505847A/en
Priority to BE692054D priority patent/BE692054A/xx
Priority to FR99163A priority patent/FR6173M/fr
Publication of GB1147798A publication Critical patent/GB1147798A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Abstract

1,147,798. Steroid 3-thioketals. H. SMITH. 7 June, 1967 [13 June, 1966; 26 Aug., 1966], Nos. 26318/66 and 38295/66. Addition to 1,041,278. Heading C2U. Novel steroids of the formula (wherein R<SP>4</SP> is H or acyl; R<SP>5</SP> is CH 3 , C 2 H 5 , ethynyl or chloroethynyl; and n is 2 or 3) and their racemates with their l-enantiomers are prepared by thioketalization of the corresponding 3-ketones or by reaction of the corresponding 17-ketones with organometallic reagents capable of providing the group R<SP>5</SP>. Resulting 17-ols may subsequently be acylated. 17-Ketone starting materials are prepared by oxidation of the corresponding 17-ols, prepared in turn by thioketalization of 13-ethyl-17#- hydroxy-gon-4-en-3-one. The steroid 3-thioketals of the invention, which are progestational agents, may be made up into pharmaceutical compositions with suitable carriers.
GB38295/66A 1966-06-13 1966-06-13 Steroid 3-thioketals Expired GB1147798A (en)

Priority Applications (12)

Application Number Priority Date Filing Date Title
GB38295/66A GB1147798A (en) 1966-06-13 1966-06-13 Steroid 3-thioketals
SE13130/66A SE325568B (en) 1966-06-13 1966-09-29
ES0331807A ES331807A1 (en) 1966-06-13 1966-09-30 A procedure to prepare a tiocetal. (Machine-translation by Google Translate, not legally binding)
DK510666AA DK114343B (en) 1966-06-13 1966-10-03 Analogous process for the preparation of 3,3-alkylenedithio-13β-ethylgon-4-ones.
NL666614507A NL153881B (en) 1966-06-13 1966-10-14 PROCESS FOR PREPARING MEDICINAL PRODUCTS WITH PROGESTIVE ACTIVITY BASED ON A 13 BETA-ETHYL-17 BETA-HYDROXY-GONE-4 COMPOUND, AS WELL AS FORMED MEDICINAL PRODUCT AND PROCESS FOR PREPARATION OF MEDICINAL PRODUCTS.
DE19661593448 DE1593448B1 (en) 1966-06-13 1966-10-19 13ss-AEthyl-gon-4-en-3-on-thioketals, their production and use
CH1521166A CH473112A (en) 1966-06-13 1966-10-20 Process for the preparation of thioketals
YU2101/66A YU32919B (en) 1966-06-13 1966-11-08 Postupak za dobijanje tioketala
BR184711/66A BR6684711D0 (en) 1966-06-13 1966-11-18 PROCESS FOR THE PREPARATION OF STEROID COMPOUNDS
FR88010A FR1505847A (en) 1966-06-13 1966-12-19 Process for the preparation of steroid compounds
BE692054D BE692054A (en) 1966-06-13 1966-12-30
FR99163A FR6173M (en) 1966-06-13 1967-03-17

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB38295/66A GB1147798A (en) 1966-06-13 1966-06-13 Steroid 3-thioketals
GB3829566 1966-08-26

Publications (1)

Publication Number Publication Date
GB1147798A true GB1147798A (en) 1969-04-10

Family

ID=26258189

Family Applications (1)

Application Number Title Priority Date Filing Date
GB38295/66A Expired GB1147798A (en) 1966-06-13 1966-06-13 Steroid 3-thioketals

Country Status (11)

Country Link
BE (1) BE692054A (en)
BR (1) BR6684711D0 (en)
CH (1) CH473112A (en)
DE (1) DE1593448B1 (en)
DK (1) DK114343B (en)
ES (1) ES331807A1 (en)
FR (2) FR1505847A (en)
GB (1) GB1147798A (en)
NL (1) NL153881B (en)
SE (1) SE325568B (en)
YU (1) YU32919B (en)

Also Published As

Publication number Publication date
BR6684711D0 (en) 1973-12-27
BE692054A (en) 1967-06-30
FR1505847A (en) 1967-12-15
DE1593448B1 (en) 1971-11-25
NL153881B (en) 1977-07-15
YU210166A (en) 1975-06-30
CH473112A (en) 1969-05-31
YU32919B (en) 1975-12-31
FR6173M (en) 1968-07-08
SE325568B (en) 1970-07-06
ES331807A1 (en) 1967-07-01
DK114343B (en) 1969-06-23
NL6614507A (en) 1967-12-14

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