GB1141074A - Process for the manufacture of 17-‡,21-dihydroxy-20-keto-steroids - Google Patents
Process for the manufacture of 17-‡,21-dihydroxy-20-keto-steroidsInfo
- Publication number
- GB1141074A GB1141074A GB27460/66A GB2746066A GB1141074A GB 1141074 A GB1141074 A GB 1141074A GB 27460/66 A GB27460/66 A GB 27460/66A GB 2746066 A GB2746066 A GB 2746066A GB 1141074 A GB1141074 A GB 1141074A
- Authority
- GB
- United Kingdom
- Prior art keywords
- steroids
- oxo
- hydroxy
- keto
- dihydroxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000007858 starting material Substances 0.000 abstract 2
- RYHBNJHYFVUHQT-UHFFFAOYSA-N 1,4-Dioxane Chemical compound C1COCCO1 RYHBNJHYFVUHQT-UHFFFAOYSA-N 0.000 abstract 1
- KRHYYFGTRYWZRS-UHFFFAOYSA-N Fluorane Chemical compound F KRHYYFGTRYWZRS-UHFFFAOYSA-N 0.000 abstract 1
- 229930194542 Keto Natural products 0.000 abstract 1
- LOMVENUNSWAXEN-UHFFFAOYSA-N Methyl oxalate Chemical compound COC(=O)C(=O)OC LOMVENUNSWAXEN-UHFFFAOYSA-N 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- GNVMUORYQLCPJZ-UHFFFAOYSA-N carbamothioic s-acid Chemical compound NC(S)=O GNVMUORYQLCPJZ-UHFFFAOYSA-N 0.000 abstract 1
- KXDHJXZQYSOELW-UHFFFAOYSA-N carbonic acid monoamide Natural products NC(O)=O KXDHJXZQYSOELW-UHFFFAOYSA-N 0.000 abstract 1
- 150000002118 epoxides Chemical class 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 229910000040 hydrogen fluoride Inorganic materials 0.000 abstract 1
- 230000001678 irradiating effect Effects 0.000 abstract 1
- XGZVUEUWXADBQD-UHFFFAOYSA-L lithium carbonate Chemical compound [Li+].[Li+].[O-]C([O-])=O XGZVUEUWXADBQD-UHFFFAOYSA-L 0.000 abstract 1
- 229910052808 lithium carbonate Inorganic materials 0.000 abstract 1
- -1 methylenedioxy steroids Chemical class 0.000 abstract 1
- 150000003431 steroids Chemical class 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- KJAMZCVTJDTESW-UHFFFAOYSA-N tiracizine Chemical compound C1CC2=CC=CC=C2N(C(=O)CN(C)C)C2=CC(NC(=O)OCC)=CC=C21 KJAMZCVTJDTESW-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH963365A CH462159A (de) | 1965-07-09 | 1965-07-09 | Verfahren zur Herstellung von 17a,21-Dihydroxy-20-keto-steroiden |
| CH513366 | 1966-04-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1141074A true GB1141074A (en) | 1969-01-22 |
Family
ID=25697054
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB27460/66A Expired GB1141074A (en) | 1965-07-09 | 1966-06-20 | Process for the manufacture of 17-‡,21-dihydroxy-20-keto-steroids |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US3423437A (enExample) |
| CH (1) | CH462159A (enExample) |
| DE (1) | DE1568296C3 (enExample) |
| GB (1) | GB1141074A (enExample) |
| NL (2) | NL6609634A (enExample) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH454132A (de) * | 1962-10-12 | 1968-04-15 | Ciba Geigy | Verfahren zur Herstellung von fluorierten Steroiden |
| US3338930A (en) * | 1965-06-01 | 1967-08-29 | Syntex Corp | Process for the hydrolysis of bismethylenedioxy derivatives |
-
0
- NL NL126749D patent/NL126749C/xx active
-
1965
- 1965-07-09 CH CH963365A patent/CH462159A/de unknown
-
1966
- 1966-05-27 US US553298A patent/US3423437A/en not_active Expired - Lifetime
- 1966-06-20 GB GB27460/66A patent/GB1141074A/en not_active Expired
- 1966-06-30 DE DE1568296A patent/DE1568296C3/de not_active Expired
- 1966-07-08 NL NL6609634A patent/NL6609634A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NL126749C (enExample) | |
| DE1568296B2 (de) | 1975-01-02 |
| CH462159A (de) | 1968-09-15 |
| US3423437A (en) | 1969-01-21 |
| DE1568296C3 (de) | 1975-08-07 |
| NL6609634A (enExample) | 1967-01-10 |
| DE1568296A1 (de) | 1970-07-16 |
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