GB1116389A - Compositions for treatment of coccidiosis - Google Patents

Compositions for treatment of coccidiosis

Info

Publication number
GB1116389A
GB1116389A GB44047/66A GB4404766A GB1116389A GB 1116389 A GB1116389 A GB 1116389A GB 44047/66 A GB44047/66 A GB 44047/66A GB 4404766 A GB4404766 A GB 4404766A GB 1116389 A GB1116389 A GB 1116389A
Authority
GB
United Kingdom
Prior art keywords
methyl
amino
compositions
halogen
optionally substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB44047/66A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF Schweiz AG
Original Assignee
Ciba AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba AG filed Critical Ciba AG
Publication of GB1116389A publication Critical patent/GB1116389A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/116—Heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
    • C07C17/16—Preparation of halogenated hydrocarbons by replacement by halogens of hydroxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/64—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
    • C07D277/66—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2 with aromatic rings or ring systems directly attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Animal Husbandry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Anticoccidiosis compositions comprise a quaternary 5 - ammonium - methyl - 4 - amino - 2 - R - pyrimidine salt, in which R represents a cycloaliphatic group optionally substituted by halogen, etherified hydroxy or mercapto groups and the ammonium nitrogen atom is part of a monocyclic or bicyclic hetercyclic radical optionally substituted by halogen, trifluoromethyl, hydroxy, alkoxy, mercapto and amino groups containing one or more double bonds, one of which extends from the ammonium nitrogen atom, and a carrier. The compositions are in the form of orally applicable, solid or liquid feedstuffs which may contain, besides conventional materials, other therapeutically useful substances, e.g. sulphonamides (examples given), antibiotics, e.g. penicillin, streptomycin, aureomycin, terramycin and tetracyclin, antiparasitic agents, e.g. methyl 4 - acetamino - 2 - ethoxy - benzoate, 2 - amino - 5 - nitrothiazole and 1 - (5 - nitro - 2 - thiazolyl) - 2 - oxo - tetrahydroimidazole, and/or tranquilizers, e.g. reserpine, methyl 18 - epi - O - methyl - reserpate and meprobamate.
GB44047/66A 1965-10-05 1966-10-03 Compositions for treatment of coccidiosis Expired GB1116389A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US49323365A 1965-10-05 1965-10-05
US53466666A 1966-03-16 1966-03-16
US57267166A 1966-08-16 1966-08-16
US592314A US3385857A (en) 1965-10-05 1966-11-07 Cycloaliphatic pyrimidines

Publications (1)

Publication Number Publication Date
GB1116389A true GB1116389A (en) 1968-06-06

Family

ID=27504357

Family Applications (2)

Application Number Title Priority Date Filing Date
GB44046/66A Expired GB1116388A (en) 1965-10-05 1966-10-03 Cycloaliphatic pyrimidines and process for their manufacture
GB44047/66A Expired GB1116389A (en) 1965-10-05 1966-10-03 Compositions for treatment of coccidiosis

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GB44046/66A Expired GB1116388A (en) 1965-10-05 1966-10-03 Cycloaliphatic pyrimidines and process for their manufacture

Country Status (14)

Country Link
US (1) US3385857A (en)
AT (2) AT277653B (en)
BE (2) BE687778A (en)
BR (2) BR6683425D0 (en)
CH (1) CH484168A (en)
DE (1) DE1670389A1 (en)
DK (1) DK122326B (en)
FI (1) FI45115C (en)
FR (1) FR1503663A (en)
GB (2) GB1116388A (en)
IL (1) IL26554A (en)
NL (2) NL6613987A (en)
NO (1) NO122650B (en)
SE (1) SE331786B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3454575A (en) * 1967-03-06 1969-07-08 Ciba Geigy Corp Quaternary 5-ammonium-methyl-4-amino-2 cycloaliphatylpyrimidine salts
BE795071A (en) * 1972-02-08 1973-08-07 Merck & Co Inc COCCIDIOSTATIC COMPOUNDS
US4006143A (en) * 1974-04-09 1977-02-01 Merck & Co., Inc. Heterocyclic substituted pyrimidine compounds
US4044133A (en) * 1974-04-18 1977-08-23 Merck & Co., Inc. Anticoccidial compositions
US6077981A (en) * 1998-08-28 2000-06-20 Eastman Chemical Company Process for the production of cyclopropylmethyl halides
US6118032A (en) * 1999-08-03 2000-09-12 Eastman Chemical Company Process for the production of cyclopropylmethyl halides
EP1234508A1 (en) * 2001-02-21 2002-08-28 Universiteit Gent Antiprotozoal methods, compositions and feedstuffs
CN111760032B (en) * 2020-07-22 2022-02-25 广州白云山宝神动物保健品有限公司 Composition for preventing and treating drug-resistant coccidiosis of chicken and preparation method and application thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3042676A (en) * 1960-02-02 1962-07-03 Merck & Co Inc Pyridinium quaternary salts and methods of preparing the same

Also Published As

Publication number Publication date
AT281040B (en) 1970-05-11
US3385857A (en) 1968-05-28
FR1503663A (en) 1967-12-01
NO122650B (en) 1971-07-26
BR6683424D0 (en) 1973-12-04
CH484168A (en) 1970-01-15
GB1116388A (en) 1968-06-06
FI45115C (en) 1972-03-10
DE1670389A1 (en) 1970-11-05
DK122326B (en) 1972-02-21
BE687778A (en) 1967-04-04
BR6683425D0 (en) 1973-12-04
NL6613986A (en) 1967-04-06
AT277653B (en) 1970-01-12
NL6613987A (en) 1967-04-06
IL26554A (en) 1971-04-28
BE687779A (en) 1967-04-04
SE331786B (en) 1971-01-11
FI45115B (en) 1971-11-30

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