GB1110664A - Amidinoureas and amidinothioureas and processes for the preparation thereof - Google Patents

Amidinoureas and amidinothioureas and processes for the preparation thereof

Info

Publication number
GB1110664A
GB1110664A GB2496966A GB2496966A GB1110664A GB 1110664 A GB1110664 A GB 1110664A GB 2496966 A GB2496966 A GB 2496966A GB 2496966 A GB2496966 A GB 2496966A GB 1110664 A GB1110664 A GB 1110664A
Authority
GB
United Kingdom
Prior art keywords
carbon atoms
alkyl
piperidinoalkyl
morpholinoalkyl
aminoalkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2496966A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
STWB Inc
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Publication of GB1110664A publication Critical patent/GB1110664A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A novel compound having the formula <FORM:1110664/C2/1> wherein X is oxygen or sulphur; Y is hydrogen, alkyl containing 1-18 carbon atoms, alkenyl containing 3-18 carbon atoms, alkoxyalkyl containing 3-17 carbon atoms, alkylthioalkyl containing 3-17 carbon atoms, cycloalkyl containing 3-8 carbon atoms, di (lower alkyl) aminoalkyl containing 4-10 carbon atoms, morpholinoalkyl containing 6-10 carbon atoms, or piperidinoalkyl containing 7-11 carbon atoms; and Y1 is alkyl containing 8-18 carbon atoms when Y is hydrogen and containing 3-18 carbon atoms when Y is other than hydrogen, alkenyl containing 3-18 carbon atoms, alkoxyalkyl containing 3-17 carbon atoms, alkylthioalkyl containing 3-17 carbon atoms, cycloalkyl containing 3-8 carbon atoms, di (lower alkyl)-aminoalkyl containing 4-10 carbon atoms, morpholinoalkyl containing 6-10 carbon atoms, or piperidinoalkyl containing 7-11 carbon atoms or an acid addition salt thereof, is obtained by reacting a 1-(Y)-guanidine having the structural formula <FORM:1110664/C2/2> with approximately one molecular equivalent of an isocyanate or isothiocyanate having the structural formula Y1-NCH and if desired obtaining an acid addition salt of the basic compound obtained.ALSO:A disinfecting and sanitising agent or a pharmaceutical composition comprises a compound having the formula: <FORM:1110664/A5-A6/1> wherein X is O or S; Y is H, alkyl containing 1-18 carbon atoms, alkenyl containing 3-18 carbon atoms, alkoxyalkyl containing 3-17 carbon atoms, alkylthioalkyl containing 3-17 carbon atoms, cycloalkyl containing 3-8 carbon atoms, di (lower alkyl) aminoalkyl containing 4-10 carbon atoms, morpholinoalkyl containing 6-10 carbon atoms, piperidinoalkyl containing 7-11 carbon atoms; and Y\sv is alkyl containing 8-18 carbon atoms when Y is H, and containing 3-18 carbon atoms when Y is other than H, alkenyl containing 3-18 carbon atoms, alkoxyalkyl containing 3-17 carbon atoms, alkylthioalkyl containing 3-17 carbon atoms, cycloalkyl containing 3-8 carbon atoms, di (lower alkyl)-aminoalkyl containing 4-10 carbon atoms, morpholinoalkyl containing 6-10 carbon atoms or piperidinoalkyl containing 7-11 carbon atoms or an acid addition salt thereof and an inert carrier. The antibacterial and antifungicidal activities may be employed in the treatment of plants and in paper-making, or the pharmaceutical compositions may be applied to living surfaces by swabbing, padding, spraying, immersing and rinsing.
GB2496966A 1965-06-07 1966-06-03 Amidinoureas and amidinothioureas and processes for the preparation thereof Expired GB1110664A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US46207765A 1965-06-07 1965-06-07

Publications (1)

Publication Number Publication Date
GB1110664A true GB1110664A (en) 1968-04-24

Family

ID=23835083

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2496966A Expired GB1110664A (en) 1965-06-07 1966-06-03 Amidinoureas and amidinothioureas and processes for the preparation thereof

Country Status (4)

Country Link
BE (1) BE682190A (en)
FR (1) FR5617M (en)
GB (1) GB1110664A (en)
NL (1) NL6607845A (en)

Also Published As

Publication number Publication date
NL6607845A (en) 1966-12-08
BE682190A (en) 1966-12-07
FR5617M (en) 1967-12-11

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